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Issues

Volume 60, Issue 12
15 June 2000
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Advances in Brief

Pancreatic Duct Cell Carcinomas Express High Levels of High Mobility Group I(Y) Proteins
Nobutsugu Abe; Takashi Watanabe; Tadahiko Masaki; Toshiyuki Mori; Masanori Sugiyama; Hidemasa Uchimura; Yasunori Fujioka; Gennaro Chiappetta; Alfredo Fusco; Yutaka Atomi
View articletitled, Pancreatic Duct Cell Carcinomas Express High Levels of High Mobility Group I(Y) Proteins
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Inhibition of Angiogenesis and Induction of Apoptosis Are Involved in E1A-mediated Bystander Effect and Tumor Suppression1
Ruping Shao; Weiya Xia; Mien-Chie Hung
View articletitled, Inhibition of Angiogenesis and Induction of Apoptosis Are Involved in E1A-mediated Bystander Effect and Tumor Suppression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Pyrido[2,3-d]pyrimidine Derivative PD180970 Inhibits p210Bcr-Abl Tyrosine Kinase and Induces Apoptosis of K562 Leukemic Cells1
Jay F. Dorsey; Richard Jove; Alan J. Kraker; Jie Wu
View articletitled, The Pyrido[2,3-<em>d</em>]pyrimidine Derivative PD180970 Inhibits p210<sup>Bcr-Abl</sup> Tyrosine Kinase and Induces Apoptosis of K562 Leukemic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Vaccine-induced Apoptosis: A Novel Clinical Trial End Point?1
Schwann Amin; R. Adrian Robins; Charles A. Maxwell-Armstrong; John H. Scholefield; Lindy G. Durrant
View articletitled, Vaccine-induced Apoptosis: A Novel Clinical Trial End Point?<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A Novel Histone Deacetylase Inhibitor Identified by High-Throughput Transcriptional Screening of a Compound Library1
Gloria H. Su; Taylor A. Sohn; Byungwoo Ryu; Scott E. Kern
View articletitled, A Novel Histone Deacetylase Inhibitor Identified by High-Throughput Transcriptional Screening of a Compound Library<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Genomic Structure of the Human ING1 Gene and Tumor-specific Mutations Detected in Head and Neck Squamous Cell Carcinomas1
Mehmet Gunduz; Mamoru Ouchida; Kunihiro Fukushima; Hiroko Hanafusa; Tsutomu Etani; Shinji Nishioka; Kazunori Nishizaki; Kenji Shimizu
View articletitled, Genomic Structure of the Human <em>ING1</em> Gene and Tumor-specific Mutations Detected in Head and Neck Squamous Cell Carcinomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Functional Evaluation of PTEN Missense Mutations Using in Vitro Phosphoinositide Phosphatase Assay1
Shuang-Yin Han; Hideaki Kato; Shunsuke Kato; Takao Suzuki; Hiroyuki Shibata; Seiichi Ishii; Ken-ichi Shiiba; Seiki Matsuno; Ryunosuke Kanamaru; Chikashi Ishioka
View articletitled, Functional Evaluation of <em>PTEN</em> Missense Mutations Using <em>in Vitro</em> Phosphoinositide Phosphatase Assay<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Cysteine 230 Modulates Tumor Necrosis Factor-related Apoptosis-inducing Ligand Activity1
Dai-Wu Seol; Timothy R. Billiar
View articletitled, Cysteine 230 Modulates Tumor Necrosis Factor-related Apoptosis-inducing Ligand Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Alcohol Consumption and Cigarette Smoking Increase the Frequency of p53 Mutations in Non-Small Cell Lung Cancer1
Steven A. Ahrendt; John T. Chow; Stephen C. Yang; Li Wu; Mei-Jie Zhang; Jin Jen; David Sidransky
View articletitled, Alcohol Consumption and Cigarette Smoking Increase the Frequency of <em>p53</em> Mutations in Non-Small Cell Lung Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Carcinogenesis

Consistent and Fast Inhibition of Colon Carcinogenesis by Polyethylene Glycol in Mice and Rats Given Various Carcinogens1
Denis E. Corpet; Géraldine Parnaud; Maxence Delverdier; Ginette Peiffer; Sylviane Taché
View articletitled, Consistent and Fast Inhibition of Colon Carcinogenesis by Polyethylene Glycol in Mice and Rats Given Various Carcinogens<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Instability of X Chromosome Methylation in Aberrant Crypt Foci of the Human Colon1
Nobuyuki Sakurazawa; Noritake Tanaka; Masahiko Onda; Hiroyasu Esumi
View articletitled, Instability of X Chromosome Methylation in Aberrant Crypt Foci of the Human Colon<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Clinical Investigations

Detection of Germ-Cell Tumor Cells in the Peripheral Blood by Nested Reverse Transcription-Polymerase Chain Reaction for α-Fetoprotein-Messenger RNA and β Human Chorionic Gonadotropin-Messenger RNA1
Andreas L. A. Hautkappe; Mengji Lu; Hendrik Mueller; Axel Bex; Andreas Harstrick; Michael Roggendorf; Herbert Ruebben
View articletitled, Detection of Germ-Cell Tumor Cells in the Peripheral Blood by Nested Reverse Transcription-Polymerase Chain Reaction for α-Fetoprotein-Messenger RNA and β Human Chorionic Gonadotropin-Messenger RNA<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Endocrinology

Expression of Estrogen Receptor (ER)-α and ER-β in Normal and Malignant Prostatic Epithelial Cells: Regulation by Methylation and Involvement in Growth Regulation1
Kin-Mang Lau; Mark LaSpina; John Long; Shuk-Mei Ho
View articletitled, Expression of Estrogen Receptor (ER)-α and ER-β in Normal and Malignant Prostatic Epithelial Cells: Regulation by Methylation and Involvement in Growth Regulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Identification of Functional Estrogen Response Elements in the Gene Coding for the Potent Angiogenic Factor Vascular Endothelial Growth Factor1
Salman M. Hyder; Zafar Nawaz; Constance Chiappetta; George M. Stancel
View articletitled, Identification of Functional Estrogen Response Elements in the Gene Coding for the Potent Angiogenic Factor Vascular Endothelial Growth Factor<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Epidemiology

Chemopreventive Effects of Dietary Folate on Intestinal Polyps in Apc+/− Msh2−/− Mice1
Jacquelin Song; Kyoung-Jin Sohn; Alan Medline; Colleen Ash; Steven Gallinger; Young-In Kim
View articletitled, Chemopreventive Effects of Dietary Folate on Intestinal Polyps in <em>Apc</em>+/− <em>Msh2</em>−/− Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Experimental Therapeutics

Regrowth of 5-Fluorouracil-treated Human Colon Cancer Cells Is Prevented by the Combination of Interferon γ, Indomethacin, and Phenylbutyrate1
Yicong Huang; Curt M. Horvath; Samuel Waxman
View articletitled, Regrowth of 5-Fluorouracil-treated Human Colon Cancer Cells Is Prevented by the Combination of Interferon γ, Indomethacin, and Phenylbutyrate<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Addition of Matrix Metalloproteinase Inhibition to Conventional Cytotoxic Therapy Reduces Tumor Implantation and Prolongs Survival in a Murine Model of Human Pancreatic Cancer
Mahmudul Haq; Alexis Shafii; Emmanuel E. Zervos; Alexander S. Rosemurgy
View articletitled, Addition of Matrix Metalloproteinase Inhibition to Conventional Cytotoxic Therapy Reduces Tumor Implantation and Prolongs Survival in a Murine Model of Human Pancreatic Cancer
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Mitochondrial Amplification of Death Signals Determines Thymidine Kinase/Ganciclovir-triggered Activation of Apoptosis1
Christian Beltinger; Simone Fulda; Thomas Kammertoens; Wolfgang Uckert; Klaus-Michael Debatin
View articletitled, Mitochondrial Amplification of Death Signals Determines Thymidine Kinase/Ganciclovir-triggered Activation of Apoptosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Cancer Gene Therapy by Thyroid Hormone-mediated Expression of Toxin Genes1
Verónica Martín; Maria Luisa Cortés; Pablo de Felipe; Antonella Farsetti; Nora B. Calcaterra; Marta Izquierdo
View articletitled, Cancer Gene Therapy by Thyroid Hormone-mediated Expression of Toxin Genes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Agonistic Properties and in Vivo Antitumor Activity of the Anti-CD40 Antibody SGN-14
Joseph A. Francisco; Karen L. Donaldson; Dana Chace; Clay B. Siegall; Alan F. Wahl
View articletitled, Agonistic Properties and <em>in Vivo</em> Antitumor Activity of the Anti-CD40 Antibody SGN-14
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In Vivo Antitumor Activity and Host Toxicity of Methoxymorpholinyl Doxorubicin: Role of Cytochrome P450 3A1
Luigi Quintieri; Antonio Rosato; Eleonora Napoli; Francesco Sola; Cristina Geroni; Maura Floreani; Paola Zanovello
View articletitled, <em>In Vivo</em> Antitumor Activity and Host Toxicity of Methoxymorpholinyl Doxorubicin: Role of Cytochrome P450 3A<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Immunology

Differences in Dendritic Cells Stimulated in Vivo by Tumors Engineered to Secrete Granulocyte-Macrophage Colony-stimulating Factor or Flt3-Ligand1
Nicolas Mach; Silke Gillessen; S. Brian Wilson; Christine Sheehan; Martin Mihm; Glenn Dranoff
View articletitled, Differences in Dendritic Cells Stimulated <em>in Vivo</em> by Tumors Engineered to Secrete Granulocyte-Macrophage Colony-stimulating Factor or Flt3-Ligand<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Genetically Modified Dendritic Cells Prime Autoreactive T Cells through a Pathway Independent of CD40L and Interleukin 12: Implications for Cancer Vaccines1
Yonghong Wan; Jonathan Bramson; Andrew Pilon; Qing Zhu; Jack Gauldie
View articletitled, Genetically Modified Dendritic Cells Prime Autoreactive T Cells through a Pathway Independent of CD40L and Interleukin 12: Implications for Cancer Vaccines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Construction, Production, and Characterization of Humanized Anti-Lewis Y Monoclonal Antibody 3S193 for Targeted Immunotherapy of Solid Tumors
Andrew M. Scott; Detlef Geleick; Michael Rubira; Kerrie Clarke; Edouard C. Nice; Fiona E. Smyth; Elisabeth Stockert; Elizabeth C. Richards; Frank J. Carr; William J. Harris; Kathryn L. Armour; Jeff Rood; Anna Kypridis; Veronika Kronina; Roger Murphy; F-T. Lee; Zhanqi Liu; Kunio Kitamura; Gerd Ritter; Katrina Laughton; Eric Hoffman; Antony W. Burgess; Lloyd J. Old
View articletitled, Construction, Production, and Characterization of Humanized Anti-Lewis Y Monoclonal Antibody 3S193 for Targeted Immunotherapy of Solid Tumors
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Molecular Biology and Genetics

Epigenetic Regulation of the MGMT and hMSH6 DNA Repair Genes in Cells Resistant to Methylating Agents1
Alessandra Bearzatto; Marta Szadkowski; Peter Macpherson; Josef Jiricny; Peter Karran
View articletitled, Epigenetic Regulation of the <em>MGMT</em> and <em>hMSH6</em> DNA Repair Genes in Cells Resistant to Methylating Agents<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Unique Anti-Activator Protein-1 Activity of Retinoic Acid Receptor β1
Feng Lin; Dongmei Xiao; Siva Kumar Kolluri; Xiao-kun Zhang
View articletitled, Unique Anti-Activator Protein-1 Activity of Retinoic Acid Receptor β<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Rapid and Reliable Quantification of Minimal Residual Disease in Acute Lymphoblastic Leukemia Using Rearranged Immunoglobulin and T-Cell Receptor Loci by LightCycler Technology1
Makoto Nakao; Johannes W. G. Janssen; Thomas Flohr; Claus R. Bartram
View articletitled, Rapid and Reliable Quantification of Minimal Residual Disease in Acute Lymphoblastic Leukemia Using Rearranged Immunoglobulin and T-Cell Receptor Loci by LightCycler Technology<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Inhibition of the Interferon-γ/Signal Transducers and Activators of Transcription (STAT) Pathway by Hypermethylation at a STAT-binding Site in the p21WAF1 Promoter Region1
Bin Chen; Ling He; Van H. Savell; Jesse J. Jenkins; David M. Parham
View articletitled, Inhibition of the Interferon-γ/Signal Transducers and Activators of Transcription (STAT) Pathway by Hypermethylation at a STAT-binding Site in the <em>p21</em><sup><em>WAF1</em></sup> Promoter Region<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Tumor Biology

Role for ATM in DNA Damage-induced Phosphorylation of BRCA11
Magtouf Gatei; Shaun P. Scott; Igor Filippovitch; Natasha Soronika; Martin F. Lavin; Barbara Weber; Kum Kum Khanna
View articletitled, Role for ATM in DNA Damage-induced Phosphorylation of BRCA1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Arginase Activity in Human Breast Cancer Cell Lines: Nω-Hydroxy-l-arginine Selectively Inhibits Cell Proliferation and Induces Apoptosis in MDA-MB-468 Cells1
Rajan Singh; Shehla Pervin; Ardeshir Karimi; Stephen Cederbaum; Gautam Chaudhuri
View articletitled, Arginase Activity in Human Breast Cancer Cell Lines: <em>N</em><sup>ω</sup>-Hydroxy-<span class="small-caps">l</span>-arginine Selectively Inhibits Cell Proliferation and Induces Apoptosis in MDA-MB-468 Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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New Evidence for an Extra-Hepatic Role of N-acetylglucosaminyltransferase III in the Progression of Diethylnitrosamine-induced Liver Tumors in Mice1
Xiaoping Yang; Mantu Bhaumik; Riddhi Bhattacharyya; Shih Gong; Charles E. Rogler; Pamela Stanley
View articletitled, New Evidence for an Extra-Hepatic Role of <em>N</em>-acetylglucosaminyltransferase III in the Progression of Diethylnitrosamine-induced Liver Tumors in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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