(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Perspectives in Cancer Research

Immunoprevention of Cancer: Is the Time Ripe?1

Guido Forni; Pier Luigi Lollini; Piero Musiani; Mario P. Colombo

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Advances in Brief

Effects of the Multidrug Transporter P-Glycoprotein on Cellular Responses to Ionizing Radiation 1

Adam C. Ruth; Igor B. Roninson

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Influence of Nitric Oxide Synthase II Gene Disruption on Tumor Growth and Metastasis 1

Qian Shi; Qinghua Xiong; Bailiang Wang; Xiangdong Le; Nasim A. Khan; Keping Xie

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Effects of Thomsen-Friedenreich Antigen-specific Peptide P-30 on β-Galactoside-mediated Homotypic Aggregation and Adhesion to the Endothelium of MDA-MB-435 Human Breast Carcinoma Cells 1

Vladislav V. Glinsky; Margaret E. Huflejt; Gennadi V. Glinsky; Susan L. Deutscher; Thomas P. Quinn

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Breast Cancer Resistance Protein Is Localized at the Plasma Membrane in Mitoxantrone- and Topotecan-resistant Cell Lines 1

George L. Scheffer; Marc Maliepaard; Adriana C. L. M. Pijnenborg; Margôt A. van Gastelen; Mariska C. de Jong; Anouk B. Schroeijers; Dorina M. van der Kolk; John D. Allen; Douglas D. Ross; Paul van der Valk; William S. Dalton; Jan H. M. Schellens; Rik J. Scheper

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Estradiol Induces Functional Inactivation of p53 by Intracellular Redistribution 1

Anna Maria Molinari; Paola Bontempo; Ettore M. Schiavone; Vincenzo Tortora; M. Antonietta Verdicchio; Massimo Napolitano; Ernesto Nola; Bruno Moncharmont; Nicola Medici; Vincenzo Nigro; Ignazio Armetta; Ciro Abbondanza; Giovanni A. Puca

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Monoallelic Amplification of Estrogen Receptor-α Expression in Breast Cancer 1

Eric R. Schuur; Ronald J. Weigel

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A Novel Transmembrane Serine Protease (TMPRSS3) Overexpressed in Pancreatic Cancer^1,2

Christine Wallrapp; Susanne Hähnel; Friederike Müller-Pillasch; Beata Burghardt; Takeshi Iwamura; Manuel Ruthenbürger; Markus M. Lerch; Guido Adler; Thomas M. Gress

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Excision of Tamoxifen-DNA Adducts by the Human Nucleotide Excision Repair System 1

Shinya Shibutani; Joyce T. Reardon; Naomi Suzuki; Aziz Sancar

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Radiation and the Apo2L/TRAIL Apoptotic Pathway Preferentially Inhibit the Colonization of Premalignant Human Breast Cells Overexpressing Cyclin D1

Qun Zhou; Paula Fukushima; William DeGraff; James B. Mitchell; Maryalice Stetler-Stevenson; Avi Ashkenazi; Patricia S. Steeg

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Biochemistry and Biophysics

p16^INK4A Mediates Cyclin Dependent Kinase 4 and 6 Inhibition in Senescent Prostatic Epithelial Cells 1

Charanjit Sandhu; Donna M. Peehl; Joyce Slingerland

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High and Low Fluences of α-Particles Induce a G₁ Checkpoint in Human Diploid Fibroblasts 1

Edouard I. Azzam; Sonia M. de Toledo; Anthony J. Waker; John B. Little

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Clinical Investigations

Clinical Implications of Expression of Interleukin 8 Related to Angiogenesis in Uterine Cervical Cancers

Jiro Fujimoto; Hideki Sakaguchi; Ikumi Aoki; Teruhiko Tamaya

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Experimental Therapeutics

Depletion of Tumor Oxygenation during Photodynamic Therapy: Detection by the Hypoxia Marker EF3 [2-(2-Nitroimidazol-1[H]-yl)-N-(3,3,3-trifluoropropyl)acetamide]1

Theresa M. Busch; Stephen M. Hahn; Sydney M. Evans; Cameron J. Koch

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Fas-dependent and -independent Mechanisms of Cell Death following DNA Damage in Human Colon Carcinoma Cells 1

Istvan Petak; David M. Tillman; Franklin G. Harwood; Rudolf Mihalik; Janet A. Houghton

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Induction of Apoptosis in Leukemic Cells by the Reversible Microtubule-disrupting Agent 2-Methoxy-5-(2′,3′,4′-trimethoxyphenyl)-2,4,6-cycloheptatrien-1-one: Protection by Bcl-2 and Bcl-X_L and Cell Cycle Arrest 1

Consuelo Gajate; Isabel Barasoain; José M. Andreu; Faustino Mollinedo

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Liposome-delivered Angiostatin Strongly Inhibits Tumor Growth and Metastatization in a Transgenic Model of Spontaneous Breast Cancer 1

Maria Grazia Sacco; Mario Caniatti; Enrica Mira Catò; Annalisa Frattini; Giulia Chiesa; Roberta Ceruti; Fulvio Adorni; Luigi Zecca; Eugenio Scanziani; Paolo Vezzoni

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Efficient Induction of Cell Death by Adenoviruses Requires Binding of E1B55k and p53 1

Brett R. Dix; Simon J. O’Carroll; Colleen J. Myers; Sara J. Edwards; Antony W. Braithwaite

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Two Novel 14-Epi-Analogues of 1,25-Dihydroxyvitamin D₃ Inhibit the Growth of Human Breast Cancer Cells in Vitro and in Vivo1

Lieve Verlinden; Annemieke Verstuyf; Mark Van Camp; Suzanne Marcelis; Katrien Sabbe; Xu-Yang Zhao; Pierre De Clercq; Maurits Vandewalle; Roger Bouillon

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Mouse Mammary Tumor Virus-Ki-rasB Transgenic Mice Develop Mammary Carcinomas That Can Be Growth-inhibited by a Farnesyl:Protein Transferase Inhibitor

Charles A. Omer; Zunxuan Chen; Ronald E. Diehl; Michael W. Conner; Howard Y. Chen; Myrna E. Trumbauer; Shobhna Gopal-Truter; Gina Seeburger; Hema Bhimnathwala; Marc T. Abrams; Joseph P. Davide; Michelle S. Ellis; Jackson B. Gibbs; Ian Greenberg; Kelly Hamilton; Kenneth S. Koblan; Astrid M. Kral; Dongming Liu; Robert B. Lobell; Patricia J. Miller; Scott D. Mosser; Timothy J. O’Neill; Elaine Rands; Michael D. Schaber; Edith T. Senderak; Allen Oliff; Nancy E. Kohl

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Recombinant Adenovirus Vaccine Encoding a Chimeric T-Cell Antigen Receptor Induces Protective Immunity against a T-Cell Lymphoma 1

Carmen P. Wong; Ronald Levy

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Methioninase Gene Therapy of Human Cancer Cells Is Synergistic with Recombinant Methioninase Treatment

Kenji Miki; Waddah Al-Refaie; Mingxu Xu; Ping Jiang; Yuying Tan; Michael Bouvet; Ming Zhao; Anshu Gupta; Takashi Chishima; Hiroshi Shimada; Masatoshi Makuuchi; A. R. Moossa; Robert M. Hoffman

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Immunology

Endogenous Interleukin-18 Modulates Immune Escape of Murine Melanoma Cells by Regulating the Expression of Fas Ligand and Reactive Oxygen Intermediates 1

Daeho Cho; Hyunkeun Song; Yong Man Kim; Dong Houh; Dae Young Hur; Hyunjeong Park; Doyoung Yoon; Kwang Ho Pyun; Wang Jae Lee; Masashi Kurimoto; Yoon Berm Kim; Young Sang Kim; Inpyo Choi

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Cooperativity of Staphylococcal aureus Enterotoxin B Superantigen, Major Histocompatibility Complex Class II, and CD80 for Immunotherapy of Advanced Spontaneous Metastases in a Clinically Relevant Postoperative Mouse Breast Cancer Model 1

Beth A. Pulaski; David S. Terman; Saleem Khan; Eric Muller; Suzanne Ostrand-Rosenberg

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Molecular Biology and Genetics

Comparison of TP53 Mutations Identified by Oligonucleotide Microarray and Conventional DNA Sequence Analysis 1

Wen-Hsiang Wen; Leslie Bernstein; Jennifer Lescallett; Yasmin Beazer-Barclay; Jane Sullivan-Halley; Marga White; Michael F. Press

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Cytoplasmic Sequestration and Functional Repression of p53 in the Mammary Epithelium Is Reversed by Hormonal Treatment 1

Charlotte Kuperwasser; Jan Pinkas; Gregory D. Hurlbut; Stephen P. Naber; D. Joseph Jerry

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Tumor Biology

Small Cell Lung Carcinoma Exhibits Greater Phospholipase C-β1 Expression and Edelfosine Resistance Compared with Non-Small Cell Lung Carcinoma 1

Derek Strassheim; Shulamith H. Shafer; Scott H. Phelps; Carol L. Williams

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Inducible pRb2/p130 Expression and Growth-suppressive Mechanisms: Evidence of a pRb2/p130, p27^Kip1, and Cyclin E Negative Feedback Regulatory Loop 1

Candace M. Howard; Pier Paolo Claudio; Antonio De Luca; Peter Stiegler; Francesco Paolo Jori; Nabile M. Safdar; Mario Caputi; Kamel Khalili; Antonio Giordano

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Virology

Unique Transcription Pattern of Epstein-Barr Virus (EBV) in EBV-carrying Gastric Adenocarcinomas: Expression of the Transforming BARF1 Gene 1

Axel zur Hausen; Antoinette A. T. P. Brink; Mikael E. Craanen; Jaap M. Middeldorp; Chris J. L. M. Meijer; Adriaan J. C. van den Brule

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Table of Contents

Perspectives in Cancer Research

Advances in Brief

Biochemistry and Biophysics

Clinical Investigations

Experimental Therapeutics

Immunology

Molecular Biology and Genetics

Tumor Biology

Virology

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