(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Advances in Brief

A Public Database for Gene Expression in Human Cancers 1

Anita Lal; Alex E. Lash; Stephen F. Altschul; Victor Velculescu; Lin Zhang; Roger E. McLendon; Marco A. Marra; Christa Prange; Patrice J. Morin; Kornelia Polyak; Nickolas Papadopoulos; Bert Vogelstein; Kenneth W. Kinzler; Robert L. Strausberg; Gregory J. Riggins

Abstract

View article

The Nuclear Pore Complex Protein Nup88 Is Overexpressed in Tumor Cells 1

Nerea Martínez; Angel Alons; María Dolores Moragues; José Pontón; José Schneider

Abstract

View article

Antiangiogenic Therapy Targeting the Tyrosine Kinase Receptor for Vascular Endothelial Growth Factor Receptor Inhibits the Growth of Colon Cancer Liver Metastasis and Induces Tumor and Endothelial Cell Apoptosis 1

Raymond M. Shaheen; Darren W. Davis; Wenbiao Liu; Brian K. Zebrowski; Michael R. Wilson; Corazon D. Bucana; David J. McConkey; Gerald McMahon; Lee M. Ellis

Abstract

View article

Characterization of a Duocarmycin-DNA Adduct-recognizing Protein in Cancer Cells

Akira Asai; Keiichi Yano; Tamio Mizukami; Hirofumi Nakano

Abstract

View article

Increased Expression of Estrogen Receptor β mRNA in Tamoxifen-resistant Breast Cancer Patients 1

Valerie Speirs; Carmel Malone; David S. Walton; Michael J. Kerin; Stephen L. Atkin

Abstract

View article

Expression of Wild-Type Estrogen Receptor β and Variant Isoforms in Human Breast Cancer 1

Suzanne A. W. Fuqua; Rachel Schiff; Irma Parra; William E. Friedrichs; Jui-Lan Su; David D. McKee; Kimberly Slentz-Kesler; Linda B. Moore; Timothy M. Willson; John T. Moore

Abstract

View article

Oligodeoxynucleotides Containing CpG Motifs Can Induce Rejection of a Neuroblastoma in Mice 1

Antoine F. Carpentier; Lin Chen; Fabrice Maltonti; Jean-Yves Delattre

Abstract

View article

Flavopiridol, a Protein Kinase Inhibitor, Down-Regulates Hypoxic Induction of Vascular Endothelial Growth Factor Expression in Human Monocytes

Giovanni Melillo; Edward A. Sausville; Kiona Cloud; Tyler Lahusen; Luigi Varesio; Adrian M. Senderowicz

Abstract

View article

Aberrant Methylation in Gastric Cancer Associated with the CpG Island Methylator Phenotype 1

Minoru Toyota; Nita Ahuja; Hiromu Suzuki; Fumio Itoh; Mutsumi Ohe-Toyota; Kohzoh Imai; Stephen B. Baylin; Jean-Pierre J. Issa

Abstract

View article

Predominant Expression of Alternative PAX3 and PAX7 Forms in Myogenic and Neural Tumor Cell Lines 1

Frederic G. Barr; Julie C. Fitzgerald; Jill P. Ginsberg; Michelle L. Vanella; Richard J. Davis; Jeannette L. Bennicelli

Abstract

View article

Frequent Loss of Imprinting of PEG1/MEST in Invasive Breast Cancer

Inge S. Pedersen; Peter A. Dervan; Dennise Broderick; Michèele Harrison; Nicola Miller; Emma Delany; Donal O’Shea; Paul Costello; Alo McGoldrick; George Keating; Brendan Tobin; Tom Gorey; Amanda McCann

Abstract

View article

Quantitative and Temporal Correlation between Circulating Cell-Free Epstein-Barr Virus DNA and Tumor Recurrence in Nasopharyngeal Carcinoma 1

Y. M. Dennis Lo; Lisa Y. S. Chan; Anthony T. C. Chan; Sing-Fai Leung; Kwok-Wai Lo; Jun Zhang; Joseph C. K. Lee; N. Magnus Hjelm; Philip J. Johnson; Dolly P. Huang

Abstract

View article

Lack of Involvement of Ataxia Telangiectasia Mutated (ATM) in Regulation of Nuclear Factor-κB (NF-κB) in Human Diploid Fibroblasts 1

Brian P. Ashburner; Rodney E. Shackelford; Albert S. Baldwin, Jr.; Richard S. Paules

Abstract

View article

Apoptotic Conversion: Evidence for Exchange of Genetic Information between Prostate Cancer Cells Mediated by Apoptosis 1

Alexandre de la Taille; Min-Wei Chen; Martin Burchardt; Dominique K. Chopin; Ralph Buttyan

Abstract

View article

Combining Serial Analysis of Gene Expression and Array Technologies to Identify Genes Differentially Expressed in Breast Cancer 1

Mariana Nacht; Anne T. Ferguson; Wen Zhang; Joseph M. Petroziello; Brian P. Cook; Yu Hong Gao; Sharon Maguire; Deborah Riley; George Coppola; Gregory M. Landes; Stephen L. Madden; Saraswati Sukumar

Abstract

View article

Cryptic Epitopes on α-Fetoprotein Induce Spontaneous Immune Responses in Hepatocellular Carcinoma, Liver Cirrhosis, and Chronic Hepatitis Patients 1

Roberto Bei; Alfredo Budillon; Maria Gabriella Reale; Gaetano Capuano; Domenico Pomponi; Gabriele Budillon; Luigi Frati; Raffaella Muraro

Abstract

View article

Epidermal Growth Factor Promotes MDA-MB-231 Breast Cancer Cell Migration through a Phosphatidylinositol 3′-Kinase and Phospholipase C-dependent Mechanism 1

John T. Price; Tony Tiganis; Anurag Agarwal; Daniel Djakiew; Erik W. Thompson

Abstract

View article

The PTEN Lipid Phosphatase Domain Is Not Required to Inhibit Invasion of Glioma Cells 1

Daniel Maier; Graham Jones; Xinwei Li; Axel H. Schönthal; Otmar Gratzl; Erwin G. Van Meir; Adrian Merlo

Abstract

View article

Mitogen-activated Protein Kinase Kinase 4/Stress-activated Protein/Erk Kinase 1 (MKK4/SEK1), a Prostate Cancer Metastasis Suppressor Gene Encoded by Human Chromosome 17 1

Barbara A. Yoshida; Zita Dubauskas; Marina A. Chekmareva; Thomas R. Christiano; Walter M. Stadler; Carrie W. Rinker-Schaeffer

Abstract

View article

Tumorigenicity of Human Breast Cancer Is Associated with Loss of the Ca²⁺-activated Chloride Channel CLCA2 1

Achim D. Gruber; Bendicht U. Pauli

Abstract

View article

Geranylgeranylated RhoB Mediates Suppression of Human Tumor Cell Growth by Farnesyltransferase Inhibitors 1

Wei Du; George C. Prendergast

Abstract

View article

Biochemistry

Identification, Characterization, and Cloning of TIP-B1, a Novel Protein Inhibitor of Tumor Necrosis Factor-induced Lysis 1

Erica S. Berleth; Srikanth Nadadur; Alicia D. Henn; Cheryl Eppolito; Satoshi Shiojiri; Hira L. Gurtoo; M. Jane Ehrke; Enrico Mihich

Abstract

View article

Effect of a Cancer Cachectic Factor on Protein Synthesis/Degradation in Murine C₂C₁₂ Myoblasts: Modulation by Eicosapentaenoic Acid 1

Helen J. Smith; Maria J. Lorite; Michael J. Tisdale

Abstract

View article

Experimental Therapeutics

Azidothymidine and Interferon-α Induce Apoptosis in Herpesvirus-associated Lymphomas 1

Richard K. Lee; Jian-Ping Cai; Vadim Deyev; Parkash S. Gill; Lisa Cabral; Charles Wood; Ram P. Agarwal; Wenle Xia; Lawrence H. Boise; Eckhard Podack; William J. Harrington, Jr.

Abstract

View article

Adenovirus-mediated Transfer of p33^ING1 with p53 Drastically Augments Apoptosis in Gliomas 1

Nobusada Shinoura; Yukiko Muramatsu; Miyako Nishimura; Yoko Yoshida; Atsushi Saito; Tadaaki Yokoyama; Toru Furukawa; Akira Horii; Mitsuhiro Hashimoto; Akio Asai; Takaaki Kirino; Hirofumi Hamada

Abstract

View article

Determinants of Activity of the Antifolate Thymidylate Synthase Inhibitors Tomudex (ZD1694) and GW1843U89 against Mono- and MultilayeredColon Cancer Cell Lines under Folate-restricted Conditions 1

Godefridus J. Peters; Evelien Smitskamp-Wilms; Kees Smid; Herbert M. Pinedo; Gerrit Jansen

Abstract

View article

Inhibition of Angiogenesis by Blocking Activation of the Vascular Endothelial Growth Factor Receptor 2 Leads to Decreased Growth of Neurogenic Sarcomas 1

Lilyana Angelov; Bodour Salhia; Luba Roncari; Gerald McMahon; Abhijit Guha

Abstract

View article

Apoptotic Cytosol Facilitates Bax Translocation to Mitochondria That Involves Cytosolic Factor Regulated by Bcl-2 1

Masaya Nomura; Shigeomi Shimizu; Toshinori Ito; Masashi Narita; Hikaru Matsuda; Yoshihide Tsujimoto

Abstract

View article

Immunology

Strong Cytotoxic T Lymphocyte Responses to a Macrophage Inflammatory Protein 1α-expressing Tumor: Linkage between Inflammation and Specific Immunity 1

Maja Maric; Yang Liu

Abstract

View article

The Renal Cell Carcinoma-associated Antigen G250 Encodes a Human Leukocyte Antigen (HLA)-A2.1-restricted Epitope Recognized by Cytotoxic T Lymphocytes 1

Joost L. M. Vissers; I. Jolanda M. De Vries; Marco W. J. Schreurs; Linda P. H. Engelen; Egbert Oosterwijk; Carl G. Figdor; Gosse J. Adema

Abstract

View article

Molecular Biology and Genetics

Constitutional von Hippel-Lindau (VHL) Gene Deletions Detected in VHL Families by Fluorescence in Situ Hybridization 1

Svetlana D. Pack; Berton Zbar; Evgenia Pak; David O. Ault; Jeffrey S. Humphrey; Thu Pham; Kathy Hurley; Robert J. Weil; Won-Sang Park; Igor Kuzmin; Catherine Stolle; Gladys Glenn; Lance A. Liotta; Michael I. Lerman; Richard D.; Klausner W.; Marston Linehan; Zhengping Zhuang

Abstract

View article

Identification of Genes Showing Differential Expression in Antisense K-ras-transduced Pancreatic Cancer Cells with Suppressed Tumorigenicity 1

Shumpei Ohnami; Nobuyuki Matsumoto; Masaru Nakano; Kazunori Aoki; Koichi Nagasaki; Takashi Sugimura; Masaaki Terada; Teruhiko Yoshida

Abstract

View article

p53 Null Mutations Undetected by Immunohistochemical Staining Predict a Poor Outcome with Early-Stage Non-Small Cell Lung Carcinomas 1

Takehisa Hashimoto; Yoshio Tokuchi; Moriaki Hayashi; Yasuhito Kobayashi; Kazunori Nishida; Shin-ichi Hayashi; Yuichi Ishikawa; Shigehiro Tsuchiya; Ken Nakagawa; Jun-ichi Hayashi; Eiju Tsuchiya

Abstract

View article

Effect of All-trans-Retinoic Acid on c-fms Proto-oncogene [Colony-stimulating Factor 1 (CSF-1) Receptor] Expression and CSF-1-induced Invasion and Anchorage-independent Growth of Human Breast Carcinoma Cells 1

Eva Sapi; Maryann B. Flick; Karrie Tartaro; Susan Kim; Yelena Rakhlin; Sofya Rodov; Barry M. Kacinski

Abstract

View article

Tumor Biology

The Apoptotic Effects and Synergistic Interaction of Sodium Butyrate and MG132 in Human Retinoblastoma Y79 Cells 1

Michela Giuliano; Marianna Lauricella; Giuseppe Calvaruso; Maria Carabillò; Sonia Emanuele; Renza Vento; Giovanni Tesoriere

Abstract

View article

Overexpression of Laminin γ2 Chain Monomer in Invading Gastric Carcinoma Cells 1

Naohiko Koshikawa; Kayano Moriyama; Hiroyuki Takamura; Hiroto Mizushima; Yoji Nagashima; Shunsuke Yanoma; Kaoru Miyazaki

Abstract

View article

Assessment of Vascular Maturation in Non-Small Cell Lung Cancer Using a Novel Basement Membrane Component, LH39: Correlation with p53 and Angiogenic Factor Expression

Stelios Kakolyris; Alexandra Giatromanolaki; Michael Koukourakis; Irene M. Leigh; Vassilis Georgoulias; Panagiotis Kanavaros; Efthimios Sivridis; Kevin C. Gatter; Adrian L. Harris

Abstract

View article

Expression of the Ets-1 Transcription Factor in Human Astrocytomas Is Associated with Fms-like Tyrosine Kinase-1 (Flt-1)/Vascular Endothelial Growth Factor Receptor-1 Synthesis and Neoangiogenesis 1

Markus M. Valter; Anja Hügel; H-J. Su Huang; Webster K. Cavenee; Otmar D. Wiestler; Torsten Pietsch; Nicolas Wernert

Abstract

View article

Recurrent Integration of Human Papillomaviruses 16, 45, and 67 Near Translocation Breakpoints in New Cervical Cancer Cell Lines 1

Louise A. Koopman; Károly Szuhai; Jaap D. H. van Eendenburg; Vladimir Bezrookove; Gemma G. Kenter; Ed Schuuring; Hans Tanke; Gert Jan Fleuren

Abstract

View article

B-Cell Tumorigenesis in Mice Carrying a Yeast Artificial Chromosome-based Immunoglobulin Heavy/c-myc Translocus Is Independent of the Heavy Chain Intron Enhancer (Eμ)1

Concepción Palomo; Xiangang Zou; Ian C. Nicholson; Christoph Bützler; Marianne Brüggemann

Abstract

View article

Email alerts

eTOC Alert

Latest
Most Read
Most Cited

Translating "Big Data" in Oncology for Clinical Benefit: Progress or Paralysis

Activity and resistance of a brain-permeable paradox breaker BRAF inhibitor in melanoma brain metastasis

Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer

Drug-tolerant persister cells in cancer therapy resistance

Issues

Journal Archive

Table of Contents

Advances in Brief

Biochemistry

Experimental Therapeutics

Immunology

Molecular Biology and Genetics

Tumor Biology

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only