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Issues

Volume 59, Issue 16
15 August 1999
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Advances in Brief

Abnormal Regulation of DNA Methyltransferase Expression during Colorectal Carcinogenesis1
Angelo M. De Marzo; Valerie L. Marchi; Eddy S. Yang; Ravi Veeraswamy; Xiaohui Lin; William G. Nelson
View articletitled, Abnormal Regulation of DNA Methyltransferase Expression during Colorectal Carcinogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Multimodal Cancer Treatment Mediated by a Replicating Oncolytic Virus That Delivers the Oxazaphosphorine/Rat Cytochrome P450 2B1 and Ganciclovir/Herpes Simplex Virus Thymidine Kinase Gene Therapies1
Manish Aghi; Ting Chao Chou; Kristen Suling; Xandra O. Breakefield; E. Antonio Chiocca
View articletitled, Multimodal Cancer Treatment Mediated by a Replicating Oncolytic Virus That Delivers the Oxazaphosphorine/Rat Cytochrome P450 2B1 and Ganciclovir/Herpes Simplex Virus Thymidine Kinase Gene Therapies<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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FHIT Loss of Function in Human Primary Breast Cancer Correlates with Advanced Stage of the Disease1
Manuela Campiglio; Yuri Pekarsky; Sylvie Menard; Elda Tagliabue; Silvana Pilotti; Carlo M. Croce
View articletitled, <em>FHIT</em> Loss of Function in Human Primary Breast Cancer Correlates with Advanced Stage of the Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Frequent Deletion of hSNF5/INI1, a Component of the SWI/SNF Complex, in Chronic Myeloid Leukemia1
Francis Grand; Shashikant Kulkarni; Andrew Chase; John M. Goldman; Myrtle Gordon; Nicholas C. P. Cross
View articletitled, Frequent Deletion of <em>hSNF5</em>/<em>INI1</em>, a Component of the SWI/SNF Complex, in Chronic Myeloid Leukemia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Intestinal Dysplasia and Adenoma in Transgenic Mice after Overexpression of an Activated β-Catenin1
Béeatrice Romagnolo; Dominique Berrebi; Sihem Saadi-Keddoucci; Arlette Porteu; Anne-lise Pichard; Michel Peuchmaur; Alain Vandewalle; Axel Kahn; Christine Perret
View articletitled, Intestinal Dysplasia and Adenoma in Transgenic Mice after Overexpression of an Activated β-Catenin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Mutational Activation of the β-Catenin Proto-Oncogene Is a Common Event in the Development of Wilms’ Tumors1
Robert Koesters; Ruediger Ridder; Annette Kopp-Schneider; David Betts; Volker Adams; Felix Niggli; Jakob Briner; Magnus von Knebel Doeberitz
View articletitled, Mutational Activation of the β-Catenin Proto-Oncogene Is a Common Event in the Development of Wilms’ Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Common Nonsense Mutations in RAD521
Daphne W. Bell; Doke C. R. Wahrer; Deborah H. Kang; Melissa S. MacMahon; Michael G. FitzGerald; Chikashi Ishioka; Kurt J. Isselbacher; Michael Krainer; Daniel A. Haber
View articletitled, Common Nonsense Mutations in <em>RAD52</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Mosaic Allelic Insulin-like Growth Factor 2 Expression Patterns Reveal a Link between Wilms’ Tumorigenesis and Epigenetic Heterogeneity1
Rolf Ohlsson; Hengmi Cui; Liangmei He; Susan Pfeifer; Helena Malmikumpu; Shan Jiang; Andrew P. Feinberg; Fredrik Hedborg
View articletitled, Mosaic Allelic Insulin-like Growth Factor 2 Expression Patterns Reveal a Link between Wilms’ Tumorigenesis and Epigenetic Heterogeneity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Mutagenic Activation of Environmental Carcinogens by Microsomes of Gastric Mucosa with Intestinal Metaplasia1
Masayuki Tatemichi; Sachiyo Nomura; Tsutomu Ogura; Hideko Sone; Hiroshi Nagata; Hiroyasu Esumi
View articletitled, Mutagenic Activation of Environmental Carcinogens by Microsomes of Gastric Mucosa with Intestinal Metaplasia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Quantitative Analysis of Aberrant p16 Methylation Using Real-Time Quantitative Methylation-specific Polymerase Chain Reaction1
Y. M. Dennis Lo; Ivy H. N. Wong; Jun Zhang; Mark S. C. Tein; Margaret H. L. Ng; N. Magnus Hjelm
View articletitled, Quantitative Analysis of Aberrant <em>p16</em> Methylation Using Real-Time Quantitative Methylation-specific Polymerase Chain Reaction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Different Frequencies and Patterns of β-Catenin Mutations in Hepatocellular Carcinomas Induced by N-Nitrosodiethylamine and a Choline-deficient l-Amino Acid-defined Diet in Rats1
Toshifumi Tsujiuchi; Masahiro Tsutsumi; Yasutaka Sasaki; Makoto Takahama; Yoichi Konishi
View articletitled, Different Frequencies and Patterns of β-Catenin Mutations in Hepatocellular Carcinomas Induced by <em>N-</em>Nitrosodiethylamine and a Choline-deficient <span class="small-caps">l</span>-Amino Acid-defined Diet in Rats<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Cytochrome P450c17α Gene (CYP17) Polymorphism Predicts Use of Hormone Replacement Therapy1
Heather Spencer Feigelson; Roberta McKean-Cowdin; Malcolm C. Pike; Gerhard A. Coetzee; Laurence N. Kolonel; Abraham M. Y. Nomura; Loic Le Marchand; Brian E. Henderson
View articletitled, Cytochrome P450c17α Gene (<em>CYP17</em>) Polymorphism Predicts Use of Hormone Replacement Therapy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Hammerhead Ribozyme-mediated Inactivation of Mutant RET in Medullary Thyroid Carcinoma1
Ranjani Parthasarathy; Gilbert J. Cote; Robert F. Gagel
View articletitled, Hammerhead Ribozyme-mediated Inactivation of Mutant RET in Medullary Thyroid Carcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Reciprocal Positive Regulation of Hypoxia-inducible Factor 1α and Insulin-like Growth Factor 21
David Feldser; Faton Agani; Narayan V. Iyer; Brian Pak; Gloria Ferreira; Gregg L. Semenza
View articletitled, Reciprocal Positive Regulation of Hypoxia-inducible Factor 1α and Insulin-like Growth Factor 2<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Antitumor Activity of 13,14-Dihydro-15-deoxy-Δ7-prostaglandin-A1-methyl Ester Integrated into Lipid Microspheres against Human Ovarian Carcinoma Cells Resistant to Cisplatin in Vivo1
Hiroshi Sasaki; Shigeki Niimi; Minoru Akiyama; Tadao Tanaka; Atsuo Hazato; Seiji Kurozumi; Shoji Fukushima; Masanori Fukushima
View articletitled, Antitumor Activity of 13,14-Dihydro-15-deoxy-Δ<sup>7</sup>-prostaglandin-A<sub>1</sub>-methyl Ester Integrated into Lipid Microspheres against Human Ovarian Carcinoma Cells Resistant to Cisplatin <em>in Vivo</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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An Insulin-like Growth Factor-mediated, Phosphatidylinositol 3′ Kinase-independent Survival Signaling Pathway in β Tumor Cells1
Ingo Burtscher; Amelia Compagni; Gábor M. Lamm; Gerhard Christofori
View articletitled, An Insulin-like Growth Factor-mediated, Phosphatidylinositol 3′ Kinase-independent Survival Signaling Pathway in β Tumor Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Identification of a Novel Complex between Human Kallikrein 2 and Protease Inhibitor-6 in Prostate Cancer Tissue
Stephen D. Mikolajczyk; Lisa S. Millar; Kathy M. Marker; Harry G. Rittenhouse; Robert L. Wolfert; Leonard S. Marks; M. Cristine Charlesworth; Donald J. Tindall
View articletitled, Identification of a Novel Complex between Human Kallikrein 2 and Protease Inhibitor-6 in Prostate Cancer Tissue
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Decreases in Ikaros Activity Correlate with Blast Crisis in Patients with Chronic Myelogenous Leukemia
Hiroyuki Nakayama; Fumihiko Ishimaru; Nicole Avitahl; Nobuo Sezaki; Nobuharu Fujii; Koichi Nakase; Yoshifumi Ninomiya; Akira Harashima; Jun Minowada; Junjiro Tsuchiyama; Kenji Imajoh; Teruhiko Tsubota; Shunnichi Fukuda; Tatsuo Sezaki; Kensuke Kojima; Masamichi Hara; Hidetaka Takimoto; Seiichi Yorimitsu; Isao Takahashi; Akira Miyata; Shuichi Taniguchi; Yasunobu Tokunaga; Hisashi Gondo; Yoshiyuki Niho; Shinji Nakao; Taiichi Kyo; Hiroo Dohy; Nanao Kamada; Mine Harada
View articletitled, Decreases in Ikaros Activity Correlate with Blast Crisis in Patients with Chronic Myelogenous Leukemia
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Effects of Geldanamycin on Signaling through Activator-Protein 1 in Hypoxic HT29 Human Colon Adenocarcinoma Cells1
Irina A. Vasilevskaya; Peter J. O’Dwyer
View articletitled, Effects of Geldanamycin on Signaling through Activator-Protein 1 in Hypoxic HT29 Human Colon Adenocarcinoma Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Two Regions of Deletion in 9p23–24 in Sporadic Breast Cancer1
Han-Xiang An; Andreas Claas; Larissa Savelyeva; Susanne Seitz; Peter Schlag; Siegfried Scherneck; Manfred Schwab
View articletitled, Two Regions of Deletion in 9p23–24 in Sporadic Breast Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Biochemistry

P-Glycoprotein and Cytochrome P-450 3A Inhibition: Dissociation of Inhibitory Potencies1
Christoph Wandel; Richard B. Kim; Shama Kajiji; F. Peter Guengerich; Grant R. Wilkinson; Alastair J. J. Wood
View articletitled, P-Glycoprotein and Cytochrome P-450 3A Inhibition: Dissociation of Inhibitory Potencies<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Unusually High Expression of N-Acetylglucosaminyltransferase-IVa in Human Choriocarcinoma Cell Lines: A Possible Enzymatic Basis of the Formation of Abnormal Biantennary Sugar Chain1
Shinji Takamatsu; Suguru Oguri; Mari Toba Minowa; Aruto Yoshida; Katsumi Nakamura; Makoto Takeuchi; Akira Kobata
View articletitled, Unusually High Expression of <em>N</em>-Acetylglucosaminyltransferase-IVa in Human Choriocarcinoma Cell Lines: A Possible Enzymatic Basis of the Formation of Abnormal Biantennary Sugar Chain<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Growth Factor Signal Transduction Immediately after Two-Thirds Partial Hepatectomy in the Rat1
Donna Beer Stolz; Wendy M. Mars; Bryon E. Petersen; Tae-Hyoung Kim; George K. Michalopoulos
View articletitled, Growth Factor Signal Transduction Immediately after Two-Thirds Partial Hepatectomy in the Rat<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Pro-Apoptotic Drug Camptothecin Stimulates Phospholipase D Activity and Diacylglycerol Production in the Nucleus of HL-60 Human Promyelocytic Leukemia Cells1
Alberto M. Martelli; Roberta Bortul; Renato Bareggi; Giovanna Tabellini; Vittorio Grill; Giovanna Baldini; Paola Narducci
View articletitled, The Pro-Apoptotic Drug Camptothecin Stimulates Phospholipase D Activity and Diacylglycerol Production in the Nucleus of HL-60 Human Promyelocytic Leukemia Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Efficient Nucleotide Excision Repair of Cisplatin, Oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) PlatinumIntrastrand DNA Diadducts1
Joyce T. Reardon; Alexandra Vaisman; Stephen G. Chaney; Aziz Sancar
View articletitled, Efficient Nucleotide Excision Repair of Cisplatin, Oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) PlatinumIntrastrand DNA Diadducts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Carcinogenesis

Delayed Apoptotic Responses Associated with Radiation-induced Neoplastic Transformation of Human Hybrid Cells1
Marc S. Mendonca; Kelly L. Howard; Daphne L. Farrington; Lael A. Desmond; Toni M. Temples; Brendan M. Mayhugh; John J. Pink; David A. Boothman
View articletitled, Delayed Apoptotic Responses Associated with Radiation-induced Neoplastic Transformation of Human Hybrid Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Clinical Investigations

The Protein Kinase C Inhibitor CGP41251 Suppresses Cytokine Release and Extracellular Signal-regulated Kinase 2 Expression in Cancer Patients
Parames Thavasu; David Propper; Alexander McDonald; Nicola Dobbs; Trivadi Ganesan; Dennis Talbot; Jeremy Braybrook; Francesco Caponigro; Cathy Hutchison; Christopher Twelves; Anthony Man; Doriano Fabbro; Adrian Harris; Frances Balkwill
View articletitled, The Protein Kinase C Inhibitor CGP41251 Suppresses Cytokine Release and Extracellular Signal-regulated Kinase 2 Expression in Cancer Patients
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Endocrinology

Anhydroretinol Induces Oxidative Stress and Cell Death1
Yanqiu Chen; Jochen Buck; Fadila Derguini
View articletitled, Anhydroretinol Induces Oxidative Stress and Cell Death<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Experimental Therapeutics

Indole-3-Carbinol Prevents Cervical Cancer in Human Papilloma Virus Type 16 (HPV16) Transgenic Mice1
Liang Jin; Mei Qi; Da-Zhi Chen; Ann Anderson; Gaung-Yu Yang; Jeffrey M. Arbeit; Karen J. Auborn
View articletitled, Indole-3-Carbinol Prevents Cervical Cancer in Human Papilloma Virus Type 16 (HPV16) Transgenic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Enhancement of Antibody-directed Enzyme Prodrug Therapy in Colorectal Xenografts by an Antivascular Agent1
R. Barbara Pedley; Surinder K. Sharma; Geoffrey M. Boxer; Robert Boden; Stephen M. Stribbling; Lawrence Davies; Caroline J. Springer; Richard H. J. Begent
View articletitled, Enhancement of Antibody-directed Enzyme Prodrug Therapy in Colorectal Xenografts by an Antivascular Agent<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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FJ5002: A Potent Telomerase Inhibitor Identified by Exploiting the Disease-oriented Screening Program with COMPARE Analysis1
Imad Naasani; Hiroyuki Seimiya; Takao Yamori; Takashi Tsuruo
View articletitled, FJ5002: A Potent Telomerase Inhibitor Identified by Exploiting the Disease-oriented Screening Program with COMPARE Analysis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Ku Autoantigen Affects the Susceptibility to Anticancer Drugs1
Sun Hee Kim; Dooha Kim; Jeong Sil Han; Choon Sik Jeong; Byung Seon Chung; Chi Dug Kang; Gloria C. Li
View articletitled, Ku Autoantigen Affects the Susceptibility to Anticancer Drugs<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Pharmacokinetics and Antitumor Activity of a Bivalent Disulfide-stabilized Fv Immunotoxin with Improved Antigen Binding to erbB2
Tapan K. Bera; Jaye Viner; Elisabeth Brinkmann; Ira Pastan
View articletitled, Pharmacokinetics and Antitumor Activity of a Bivalent Disulfide-stabilized Fv Immunotoxin with Improved Antigen Binding to erbB2
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5,6-trans-16-ene-Vitamin D3: A New Class of Potent Inhibitors of Proliferation of Prostate, Breast, and Myeloid Leukemic Cells1
Jun-ichi Hisatake; Tetsuya Kubota; Yasuko Hisatake; Milan Uskokovic; Shigeru Tomoyasu; H. Phillip Koeffler
View articletitled, 5,6-<em>trans</em>-16-ene-Vitamin D<sub>3</sub>: A New Class of Potent Inhibitors of Proliferation of Prostate, Breast, and Myeloid Leukemic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Antisense Bcl-2 Oligodeoxynucleotides Inhibit Progression to Androgen-Independence after Castration in the Shionogi Tumor Model1
Hideaki Miyake; Anthony Tolcher; Martin E. Gleave
View articletitled, Antisense Bcl-2 Oligodeoxynucleotides Inhibit Progression to Androgen-Independence after Castration in the Shionogi Tumor Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Induction of Systemic and Therapeutic Antitumor Immunity Using Intratumoral Injection of Dendritic Cells Genetically Modified to Express Interleukin 121
Yasuhiko Nishioka; Motohiro Hirao; Paul D. Robbins; Michael T. Lotze; Hideaki Tahara
View articletitled, Induction of Systemic and Therapeutic Antitumor Immunity Using Intratumoral Injection of Dendritic Cells Genetically Modified to Express Interleukin 12<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Potent Antitumor Activity of MS-247, a Novel DNA Minor Groove Binder, Evaluated by an in Vitro and in Vivo Human Cancer Cell Line Panel1
Takao Yamori; Akio Matsunaga; Shigeo Sato; Kanami Yamazaki; Akiko Komi; Kazuhiro Ishizu; Izumi Mita; Hajime Edatsugi; Yasuhiro Matsuba; Kimiko Takezawa; Osamu Nakanishi; Hiroshi Kohno; Yuki Nakajima; Hironori Komatsu; Toshio Andoh; Takashi Tsuruo
View articletitled, Potent Antitumor Activity of MS-247, a Novel DNA Minor Groove Binder, Evaluated by an <em>in Vitro</em> and <em>in Vivo</em> Human Cancer Cell Line Panel<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Immunology

Analysis of the Cytolytic T Lymphocyte Response of Melanoma Patients to the Naturally HLA-A*0201-associated Tyrosinase Peptide 368–3761
Danila Valmori; Mikaël J. Pittet; Cedric Vonarbourg; Donata Rimoldi; Danielle Liénard; Daniel Speiser; Rod Dunbar; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
View articletitled, Analysis of the Cytolytic T Lymphocyte Response of Melanoma Patients to the Naturally HLA-A*0201-associated Tyrosinase Peptide 368–376<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Identification of a Gene Coding for a Protein Possessing Shared Tumor Epitopes Capable of Inducing HLA-A24-restricted Cytotoxic T Lymphocytes inCancer Patients1
Damu Yang; Masanobu Nakao; Shigeki Shichijo; Teruo Sasatomi; Hideo Takasu; Hajime Matsumoto; Kazunori Mori; Akihiro Hayashi; Hideaki Yamana; Kazuo Shirouzu; Kyogo Itoh
View articletitled, Identification of a Gene Coding for a Protein Possessing Shared Tumor Epitopes Capable of Inducing HLA-A24-restricted Cytotoxic T Lymphocytes inCancer Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Antitumor Effects of Interferon-ω: In Vivo Therapy of Human Tumor Xenografts in Nude Mice
Holly M. Horton; Pepe Hernandez; Suezanne E. Parker; Kerry M. Barnhart
View articletitled, Antitumor Effects of Interferon-ω: <em>In Vivo</em> Therapy of Human Tumor Xenografts in Nude Mice
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Molecular Biology and Genetics

Identification of NKIAMRE, the Human Homologue to the Mitogen-activated Protein Kinase-/Cyclin-dependent Kinase-related Protein Kinase NKIATRE, and Its Loss in Leukemic Blasts with Chromosome Arm 5q Deletion1
Michael Midmer; Rizwan Haq; Jeremy A. Squire; Brent W. Zanke
View articletitled, Identification of <em>NKIAMRE</em>, the Human Homologue to the Mitogen-activated Protein Kinase-/Cyclin-dependent Kinase-related Protein Kinase NKIATRE, and Its Loss in Leukemic Blasts with Chromosome Arm 5q Deletion<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Structure and Possible Mechanisms of TEL-AML1 Gene Fusions in Childhood Acute Lymphoblastic Leukemia1
Joseph L. Wiemels; Mel Greaves
View articletitled, Structure and Possible Mechanisms of <em>TEL-AML1</em> Gene Fusions in Childhood Acute Lymphoblastic Leukemia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Two Novel Mucin Genes Down-Regulated in Colorectal Cancer Identified by Differential Display1
Stephanie J. Williams; Michael A. McGuckin; David C. Gotley; Helen J. Eyre; Grant R. Sutherland; Toni M. Antalis
View articletitled, Two Novel Mucin Genes Down-Regulated in Colorectal Cancer Identified by Differential Display<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Nuclear Factor κB Transactivation Is Increased But Is Not Involved in the Proliferative Effects of Thioredoxin Overexpression in MCF-7 Breast Cancer Cells1
Alex J. Freemerman; Alfred Gallegos; Garth Powis
View articletitled, Nuclear Factor κB Transactivation Is Increased But Is Not Involved in the Proliferative Effects of Thioredoxin Overexpression in MCF-7 Breast Cancer Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A Lack of a Functional NAD(P)H:Quinone Oxidoreductase Allele Is Selectively Associated with Pediatric Leukemias That Have MLL Fusions1
Joseph L. Wiemels; Alistair Pagnamenta; G. Malcolm Taylor; Osborn B. Eden; Freda E. Alexander; Mel F. Greaves; United Kingdom Childhood Cancer Study Investigators
View articletitled, A Lack of a Functional NAD(P)H:Quinone Oxidoreductase Allele Is Selectively Associated with Pediatric Leukemias That Have <em>MLL</em> Fusions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A New MAGE Gene with Ubiquitous Expression Does Not Code for Known MAGE Antigens Recognized by T Cells1
Sophie Lucas; Francis Brasseur; Thierry Boon
View articletitled, A New <em>MAGE</em> Gene with Ubiquitous Expression Does Not Code for Known MAGE Antigens Recognized by T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Tumor Biology

Deficiency of Connexin43 Gap Junctions Is an Independent Marker for Breast Tumors1
Dale W. Laird; Paulina Fistouris; Gerald Batist; Lesley Alpert; Hung T. Huynh; George D. Carystinos; Moulay A. Alaoui-Jamali
View articletitled, Deficiency of Connexin43 Gap Junctions Is an Independent Marker for Breast Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Inhibition of Bladder Carcinoma Angiogenesis, Stromal Support, and Tumor Growth by Halofuginone1
Michael Elkin; Ilana Ariel; Hua-Quan Miao; Arnon Nagler; Mark Pines; Nathan de-Groot; Avraham Hochberg; Israel Vlodavsky
View articletitled, Inhibition of Bladder Carcinoma Angiogenesis, Stromal Support, and Tumor Growth by Halofuginone<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Expression Level of Bcl-2 Determines Anti- or Proapoptotic Function1
Nobusada Shinoura; Yoko Yoshida; Miyako Nishimura; Yukiko Muramatsu; Akio Asai; Takaaki Kirino; Hirofumi Hamada
View articletitled, Expression Level of Bcl-2 Determines Anti- or Proapoptotic Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Augmentation of Transvascular Transport of Macromolecules and Nanoparticles in Tumors Using Vascular Endothelial Growth Factor1
Wayne L. Monsky; Dai Fukumura; Takeshi Gohongi; Marek Ancukiewcz; Herbert A. Weich; Vladimir P. Torchilin; Fan Yuan; Rakesh K. Jain
View articletitled, Augmentation of Transvascular Transport of Macromolecules and Nanoparticles in Tumors Using Vascular Endothelial Growth Factor<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Available Volume Fraction of Macromolecules in the Extravascular Space of a Fibrosarcoma: Implications for Drug Delivery1
Ava Krol; Julie Maresca; Mark W. Dewhirst; Fan Yuan
View articletitled, Available Volume Fraction of Macromolecules in the Extravascular Space of a Fibrosarcoma: Implications for Drug Delivery<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Intragenic Mutation Analysis of the Human Epidermal Growth Factor Receptor (EGFR) Gene in Malignant Human Oral Keratinocytes1
Satoru Shintani; Kou Matsuo; Constant C. Crohin; Jim McBride; Takanori Tsuji; R. Bruce Donoff; Marshall Posner; Randy Todd; David T.W. Wong
View articletitled, Intragenic Mutation Analysis of the Human Epidermal Growth Factor Receptor (<em>EGFR</em>) Gene in Malignant Human Oral Keratinocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Cell Cycle Arrest and Inhibition of Anoikis by Galectin-3 in Human Breast Epithelial Cells1
Hyeong-Reh Choi Kim; Huei-Min Lin; Hector Biliran; Avraham Raz
View articletitled, Cell Cycle Arrest and Inhibition of Anoikis by Galectin-3 in Human Breast Epithelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Errata

H. Matsumoto et al., Cancer Res., 59: 3239–3244, 1999.
View articletitled, H. Matsumoto <em>et al.</em>, Cancer Res., <em>59: </em>3239–3244, 1999.
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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