(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Advances in Brief

Apoptosis Induced by Overexpression of hMSH2 or hMLH11

Hong Zhang; Burt Richards; Teresa Wilson; Michael Lloyd; Aaron Cranston; Andrew Thorburn; Richard Fishel; Mark Meuth

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Mammaglobin Expression in Primary, Metastatic, and Occult Breast Cancer 1

Mark A. Watson; Suzanne Dintzis; Christopher M. Darrow; Lora E. Voss; John DiPersio; Roy Jensen; Timothy P. Fleming

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Allelotype of Posterior Uveal Melanoma: Implications for a Bifurcated Tumor Progression Pathway 1

Paola Parrella; David Sidransky; Shannath L. Merbs

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N-acetyltransferase 2 Influences Cancer Prevalence in hMLH1/hMSH2 Mutation Carriers 1

Karl Heinimann; Rodney J. Scott; Pierre Chappuis; Walter Weber; Hansjakob Müller; Zuzana Dobbie; Pierre Hutter

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Clinical Implication of Expression of Platelet-derived Endothelial Cell Growth Factor (PD-ECGF) in Metastatic Lesions of Uterine Cervical Cancers

Jiro Fujimoto; Hideki Sakaguchi; Reiko Hirose; Hongwu Wen; Teruhiko Tamaya

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Association of the NAD(P)H:quinone Oxidoreductase ⁶⁰⁹C→T Polymorphism with a Decreased Lung Cancer Risk 1

Hongwei Chen; Annette Lum; Ann Seifried; Lynne R. Wilkens; Loïc Le Marchand

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Enhanced Efficacy of Transcriptionally Targeted Suicide Gene/Prodrug Therapy for Thyroid Carcinoma with the Cre-loxP System

Yuji Nagayama; Eijun Nishihara; Makoto Iitaka; Hiroyuki Namba; Shunichi Yamashita; Masami Niwa

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Arsenic Induces Apoptosis through a c-Jun NH₂-Terminal Kinase-dependent, p53-independent Pathway 1

Chuanshu Huang; Wei-ya Ma; Jingxia Li; Zigang Dong

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Role of O⁶-Alkylguanine-DNA Alkyltransferase in Protecting against Cyclophosphamide-induced Toxicity and Mutagenicity 1

Yingna Cai; Michael H. Wu; Susan M. Ludeman; David J. Grdina; M. Eileen Dolan

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α-Fetoprotein-specific Genetic Immunotherapy for Hepatocellular Carcinoma 1

Charles M. Vollmer, Jr.; Fritz C. Eilber; Lisa H. Butterfield; Antoni Ribas; Vivian B. Dissette; Andrew Koh; Lara D. Montejo; Maggie C. Lee; Kahlil J. Andrews; William H. McBride; John A. Glaspy; James S. Economou

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Alterations of Fas (APO-1/CD95) Gene in Transitional Cell Carcinomas of Urinary Bladder 1

Sug Hyung Lee; Min Sun Shin; Won Sang Park; Su Young Kim; Seung Myung Dong; Jae Ho Pi; Hun Kyung Lee; Ho Sik Kim; Ja June Jang; Choo Soung Kim; Sang Ho Kim; Jung Young Lee; Nam Jin Yoo

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Radiation-induced Mutations at the Autosomal Thymidine Kinase Locus Are Not Elevated in p53-null Cells 1

Yao-Yu Eric Chuang; Qi Chen; Howard L. Liber

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Biochemistry

Cisplatin-induced Apoptosis Proceeds by Caspase-3-dependent and -independent Pathways in Cisplatin-resistant and -sensitive Human Ovarian Cancer Cell Lines 1

Karen M. Henkels; John J. Turchi

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Carcinogenesis

Chemoprevention of Rat Prostate Carcinogenesis by Early and Delayed Administration of Dehydroepiandrosterone 1

K. V. N. Rao; William D. Johnson; Maarten C. Bosland; Ronald A. Lubet; Vernon E. Steele; Gary J. Kelloff; David L. McCormick

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Endocrinology

Estrogen Receptor Activation via Activation Function 2 Predicts Agonism of Xenoestrogens in Normal and Neoplastic Cells of the Uterine Myometrium 1

Deborah S. Hunter; Leslie C. Hodges; Peter M. Vonier; Robin Fuchs-Young; Marco M. Gottardis; Cheryl L. Walker

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Experimental Therapeutics

Use of the Glucose Starvation-inducible Glucose-regulated Protein 78 Promoter in Suicide Gene Therapy of Murine Fibrosarcoma 1

Gadi Gazit; Gene Hung; Xinke Chen; W. French Anderson; Amy S. Lee

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Fas-FasL-mediated CD4+ T-Cell Apoptosis following Stem Cell Transplantation 1

Rakesh K. Singh; Michelle L. Varney; Suleyman Buyukberber; Kazuhiko Ino; Ana G. Ageitos; Elizabeth Reed; Stefano Tarantolo; James E. Talmadge

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In Vivo Antitumor Activity of Choline Kinase Inhibitors: A Novel Target for Anticancer Drug Discovery 1

Rubén Hernández-Alcoceba; Félix Fernández; Juan Carlos Lacal

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Immunology

GD3 Ganglioside Antibody Augments Tumoricidal Capacity of Canine Blood Mononuclear Cells by Induction of Interleukin 12 1

Stuart C. Helfand; Erin B. Dickerson; Keith L. Munson; Marcia L. Padilla

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Tumor Rejection by in Vivo Administration of Anti-CD25 (Interleukin-2 Receptor α) Monoclonal Antibody 1

Shozaburo Onizuka; Isao Tawara; Jun Shimizu; Shimon Sakaguchi; Teizo Fujita; Eiichi Nakayama

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Generation of Human T-cell Responses to an HLA-A2.1-restricted Peptide Epitope Derived from α-Fetoprotein 1

Lisa H. Butterfield; Andrew Koh; Wilson Meng; Charles M. Vollmer; Antoni Ribas; Vivian Dissette; Eric Lee; John A. Glaspy; William H. McBride; James S. Economou

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Molecular Biology and Genetics

The Cancer Antiapoptosis Mouse Survivin Gene: Characterization of Locus and Transcriptional Requirements of Basal and Cell Cycle-dependent Expression 1

Fengzhi Li; Dario C. Altieri

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hSNF5/INI1 Inactivation Is Mainly Associated with Homozygous Deletions and Mitotic Recombinations in Rhabdoid Tumors 1

Marie-Françoise Rousseau-Merck; Isabella Versteege; Isabelle Legrand; Jérôme Couturier; Aline Mairal; Olivier Delattre; Alain Aurias

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Characterization of the GAGE Genes That Are Expressed in Various Human Cancers and in Normal Testis 1

Olivier De Backer; Karen C. Arden; Mauro Boretti; Valérie Vantomme; Charles De Smet; Suzanne Czekay; Carrie S. Viars; Etienne De Plaen; Francis Brasseur; Patrick Chomez; Benoît Van den Eynde; Thierry Boon; Pierre van der Bruggen

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Telomerase Activity and Human Telomerase Reverse Transcriptase mRNA Expression in Soft Tissue Tumors: Correlation with Grade, Histology, and Proliferative Activity

Pu Yan; Jean-Michel Coindre; Jean Benhattar; Fredrik T. Bosman; Louis Guillou

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LightCycler Technology for the Quantitation of bcr/abl Fusion Transcripts

Karl-Anton Kreuzer; Ulrich Lass; Alexander Bohn; Olfert Landt; Christian Andreas Schmidt

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The Human p53 Negative Regulatory Domain Mediates Inhibition of Reporter Gene Transactivation in Yeast Lacking Thioredoxin Reductase 1

Gary F. Merrill; Paul Dowell; George D. Pearson

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The SYT-SSX1 Variant of Synovial Sarcoma Is Associated with a High Rate of Tumor Cell Proliferation and Poor Clinical Outcome 1

Gunnar Nilsson; Björn Skytting; Yuntao Xie; Bertha Brodin; Roland Perfekt; Nils Mandahl; Joakim Lundeberg; Mathias Uhlén; Olle Larsson

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Tumor Biology

Two Independent Mechanisms Essential for Tumor Angiogenesis: Inhibition of Human Melanoma Xenograft Growth by Interfering with either the Vascular Endothelial Growth Factor Receptor Pathway or the Tie-2 Pathway

Gerhard Siemeister; Michael Schirner; Karin Weindel; Petra Reusch; Andreas Menrad; Dieter Marmé; Georg Martiny-Baron

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Five Different Anti-Prostate-specific Membrane Antigen (PSMA) Antibodies Confirm PSMA Expression in Tumor-associated Neovasculature 1

Sam S. Chang; Victor E. Reuter; W. D. W. Heston; Neil H. Bander; Lana S. Grauer; Paul B. Gaudin

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Testisin, a New Human Serine Proteinase Expressed by Premeiotic Testicular Germ Cells and Lost in Testicular Germ Cell Tumors 1

John D. Hooper; David L. Nicol; Joanne L. Dickinson; Helen J. Eyre; Anthony L. Scarman; John F. Normyle; Melanie A. Stuttgen; Meaghan L. Douglas; Kate A. Lakoski Loveland; Grant R. Sutherland; Toni M. Antalis

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Contribution of c-erbB-2 and Topoisomerase IIα to Chemoresistance in Ovarian Cancer 1

Jan G. Hengstler; Jost Lange; Alexandra Kett; Nadja Dornhöfer; Rolf Meinert; Michael Arand; Paul G. Knapstein; Roger Becker; Franz Oesch; Berno Tanner

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Isolation of a Novel Gene, TSP50, by a Hypomethylated DNA Fragment in Human Breast Cancer 1

Liming Yuan; Jidong Shan; Dwight De Risi; John Broome; John Lovecchio; David Gal; Vincent Vinciguerra; Hao-peng Xu

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Progranulin Gene Expression Regulates Epithelial Cell Growth and Promotes Tumor Growth in Vivo1

Zhiheng He; Andrew Bateman

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Protein Kinase C δ Involvement in Mammary Tumor Cell Metastasis 1

Susan C. Kiley; Kimberly J. Clark; Michelle Goodnough; Danny R. Welch; Susan Jaken

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Nitric Oxide Is an Initiator of Intercellular Signal Transduction for Stress Response after Hyperthermia in Mutant p53 Cells of Human Glioblastoma 1

Hideki Matsumoto; Sachiko Hayashi; Masanori Hatashita; Ken Ohnishi; Toshio Ohtsubo; Ryuhei Kitai; Hiroki Shioura; Takeo Ohnishi; Eiichi Kano

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Loss of P27^Kip1 Expression Correlates with Tumor Grade and with Reduced Disease-free Survival in Primary Superficial Bladder Cancers 1

Alessandro Sgambato; Mario Migaldi; Beatrice Faraglia; Lorella Garagnani; Gianpiero Romano; Carmela De Gaetani; Paolo Ferrari; Giovanni Capelli; Gian Paolo Trentini; Achille Cittadini

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Presence of Tumor DNA in Plasma of Breast Cancer Patients: Clinicopathological Correlations 1

Jose M. Silva; Gemma Dominguez; Jose M. Garcia; Rocio Gonzalez; Maria J. Villanueva; Fatima Navarro; Mariano Provencio; Santiago San Martin; Pilar España; Felix Bonilla

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Overexpression of the Wild Type p73 Gene in Breast Cancer Tissues and Cell Lines 1

Alex I. Zaika; Sergey Kovalev; Natalie D. Marchenko; Ute M. Moll

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The Insulin-like Growth Factor 1 Receptor Induces Transformation and Tumorigenicity of Ovarian Mesothelial Cells and Down-Regulates Their Fas-Receptor Expression

Domenico Coppola; Beatrice Saunders; Ling Fu; Weiguang Mao; Santo V. Nicosia

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Meeting Report

Tenth Annual Pezcoller Symposium: The Genetics of Cancer Susceptibility

Enrico Mihich; Louise Strong; Richard Klausner

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