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Issues

Volume 54, Issue 3
1 February 1994
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445
Issue Sections

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Articles

Loss of Heterozygosity on Chromosome 13 Is Common Only in the Biologically More Aggressive Subtypes of Ovarian Epithelial Tumors and Is Associated with Normal Retinoblastoma Gene Expression1
Timothy M. Kim; William F. Benedict; Hong-Ji Xu; Shi-Xue Hu; Jim Gosewehr; Mihaela Velicescu; Eric Yin; Jianping Zheng; Gerrit D'Ablaing; Louis Dubeau
View articletitled, Loss of Heterozygosity on Chromosome 13 Is Common Only in the Biologically More Aggressive Subtypes of Ovarian Epithelial Tumors and Is Associated with Normal Retinoblastoma Gene Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Evidence of Functional RB Protein in Epithelial Ovarian Carcinomas despite Loss of Heterozygosity at the RB Locus
Mark K. Dodson; William A. Cliby; Hong-Ji Xu; Karen A. DeLacey; Shi-Xue Hu; Gary L. Keeney; Jian Li; Karl C. Podratz; Robert B. Jenkins; William F. Benedict
View articletitled, Evidence of Functional RB Protein in Epithelial Ovarian Carcinomas despite Loss of Heterozygosity at the <em>RB</em> Locus
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The Role of p53 in Spontaneous and Radiation-induced Apoptosis in the Gastrointestinal Tract of Normal and p53-deficient Mice1
Anita J. Merritt; Christopher S. Potten; Christopher J. Kemp; John A. Hickman; Allan Balmain; David P. Lane; Peter A. Hall
View articletitled, The Role of <em>p53</em> in Spontaneous and Radiation-induced Apoptosis in the Gastrointestinal Tract of Normal and p53-deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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P-Glycoprotein-associated Cl- Currents Are Activated by Cell Swelling but Do Not Contribute to Cell Volume Regulation1
Guillermo A. Altenberg; Joachim W. Deitmer; Dessa C. Glass; Luis Reuss
View articletitled, P-Glycoprotein-associated Cl<sup>-</sup> Currents Are Activated by Cell Swelling but Do Not Contribute to Cell Volume Regulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Evaluation of the Potential Role of Class II Histocompatibility Antigen HLA-DR in Platelet/Tumor Cell Interaction
Patrizia Ferroni; Fiorella Guadagni; Antonella Spila; Francesca Martini; Pier Paolo Gazzaniga
View articletitled, Evaluation of the Potential Role of Class II Histocompatibility Antigen HLA-DR in Platelet/Tumor Cell Interaction
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Gross and Microscopic Pathology of Induced Prostatic Complex Tumors Arising in Lobund-Wistar Rats1
Michael B. Cohen; Paul M. Heidger; David M. Lubaroff
View articletitled, Gross and Microscopic Pathology of Induced Prostatic Complex Tumors Arising in Lobund-Wistar Rats<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Lack of Neurotoxicity of Oral Bisacetatoamminedichlorocyclohexylamine-platinum(IV) in Comparison to Cisplatin and Tetraplatin in the Rat1
Mark J. McKeage; Frances E. Boxall; Mervyn Jones; Kenneth R. Harrap
View articletitled, Lack of Neurotoxicity of Oral Bisacetatoamminedichlorocyclohexylamine-platinum(IV) in Comparison to Cisplatin and Tetraplatin in the Rat<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Specific Inhibition of Pre-Ribosomal RNA Processing in Extracts from the Lymphosarcoma Cells Treated with 5-Fluorouracil1
Kalpana Ghoshal; Samson T. Jacob
View articletitled, Specific Inhibition of Pre-Ribosomal RNA Processing in Extracts from the Lymphosarcoma Cells Treated with 5-Fluorouracil<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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ERBB2 (HER2/neu) Oncogene Is Frequently Amplified in Squamous Cell Carcinoma of the Uterine Cervix1
A. B. Mitra; V. V. V. S. Murty; Mahendra Pratap; P. Sodhani; R. S. K. Chaganti
View articletitled, <em>ERBB2 (HER2/neu)</em> Oncogene Is Frequently Amplified in Squamous Cell Carcinoma of the Uterine Cervix<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Frequent Loss of Chromosome 9 in Human Primary Non-Small Cell Lung Cancer1
Adrian Merlo; Edward Gabrielson; Frederic Askin; David Sidransky
View articletitled, Frequent Loss of Chromosome 9 in Human Primary Non-Small Cell Lung Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Prostacyclin as an Indicator of Preadipocyte Transformation: Studies in Vivo by Microdialysis and in Vitro1
Christian Darimont; Gérard Ailhaud; Raymond Negrel
View articletitled, Prostacyclin as an Indicator of Preadipocyte Transformation: Studies <em>in Vivo</em> by Microdialysis and <em>in Vitro</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Tumor-suppressive Activity of N03 Gene Product in v-src-transformed Rat 3Y1 Fibroblasts1
Toshinori Ozaki; Shigeru Sakiyama
View articletitled, Tumor-suppressive Activity of <em>N03</em> Gene Product in v-<em>src</em>-transformed Rat 3Y1 Fibroblasts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Analysis of the p53 Gene and Its Expression in Human Glioblastoma Cells1
Erwin G. Van Meir; Tetsuro Kikuchi; Mitsuhiro Tada; Hong Li; Annie-Claire Diserens; Brian E. Wojcik; H-J. Su Huang; Theodore Friedmann; Nicolas de Tribolet; Webster K. Cavenee
View articletitled, Analysis of the <em>p53</em> Gene and Its Expression in Human Glioblastoma Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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New Directions in Molecular Medicine
Judith E. Karp; Samuel Broder
View articletitled, New Directions in Molecular Medicine
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Drug Resistance: Genotype versus Phenotype—Thirty-second G. H. A. Clowes Memorial Award Lecture1
June L. Biedler
View articletitled, Drug Resistance: Genotype <em>versus</em> Phenotype—Thirty-second G. H. A. Clowes Memorial Award Lecture<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Blocking of in Vitro DNA Replication by Deoxycytidine Adducts of the Mutagen and Clastogen 2-Bromoacrolein1
Geertje J. M. van Beerendonk; Frank B. van Gog; Harry Vrieling; Paul G. Pearson; Sidney D. Nelson; John H. N. Meerman
View articletitled, Blocking of <em>in Vitro</em> DNA Replication by Deoxycytidine Adducts of the Mutagen and Clastogen 2-Bromoacrolein<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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The Effect of the Iron(III) Chelator, Desferrioxamine, on Iron and Transferrin Uptake by the Human Malignant Melanoma Cell1
Des Richardson; Prem Ponka; Erica Baker
View articletitled, The Effect of the Iron(III) Chelator, Desferrioxamine, on Iron and Transferrin Uptake by the Human Malignant Melanoma Cell<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Cross-Competition between Vasoactive Intestinal Peptide and Somatostatin for Binding to Tumor Cell Membrane Receptors1
Irene Virgolini; Qiong Yang; Shuren Li; Peter Angelberger; Nikolaus Neuhold; Bruno Niederle; Werner Scheithauer; Peter Valent
View articletitled, Cross-Competition between Vasoactive Intestinal Peptide and Somatostatin for Binding to Tumor Cell Membrane Receptors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Inhibition of Skin Tumorigenesis by Rosemary and Its Constituents Carnosol and Ursolic Acid1
Mou-Tuan Huang; Chi-Tang Ho; Zhi Yuan Wang; Thomas Ferraro; You-Rong Lou; Kathe Stauber; Wei Ma; Constantino Georgiadis; Jeffrey D. Laskin; Allan H. Conney
View articletitled, Inhibition of Skin Tumorigenesis by Rosemary and Its Constituents Carnosol and Ursolic Acid<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Phase I and Pharmacokinetic Study of Ormaplatin (Tetraplatin, NSC 363812) Administered on a Day 1 and Day 8 Schedule
Russell J. Schilder; Frank P. LaCreta; Raymond P. Perez; Steven W. Johnson; James M. Brennan; Andre Rogatko; Sherri Nash; Ceclia McAleer; Thomas C. Hamilton; David Roby; Robert C. Young; Robert F. Ozols; Peter J. O'Dwyer
View articletitled, Phase I and Pharmacokinetic Study of Ormaplatin (Tetraplatin, NSC 363812) Administered on a Day 1 and Day 8 Schedule
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A Prospective Cohort Study on the Relation between Meat Consumption and the Risk of Colon Cancer1
R. Alexandra Goldbohm; Piet A. van den Brandt; Pieter van 't Veer; Henny A. M. Brants; Elisabeth Dorant; Ferd Sturmans; Rudolph J. J. Hermus
View articletitled, A Prospective Cohort Study on the Relation between Meat Consumption and the Risk of Colon Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Antitumor Activity and Biochemical Effects of Aphidicolin Glycinate (NSC 303812) Alone and in Combination with Cisplatin in Vivo1
Peter J. O'Dwyer; James D. Moyer; Matthew Suffness; Steadman D. Harrison, Jr.; Richard Cysyk; Thomas C. Hamilton; Jacqueline Plowman
View articletitled, Antitumor Activity and Biochemical Effects of Aphidicolin Glycinate (NSC 303812) Alone and in Combination with Cisplatin <em>in Vivo</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Characteristics of P388/VMDRC.04, a Simple, Sensitive Model for Studying P-Glycoprotein Antagonists1
Jin-Ming Yang; Sarah Goldenberg; Michael M. Gottesman; William N. Hait
View articletitled, Characteristics of P388/VMDRC.04, a Simple, Sensitive Model for Studying P-Glycoprotein Antagonists<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Preclinical Evaluation of WR-151327: An Orally Active Chemotherapy Protector1
Dianna Green; Dennis Bensely; Philip Schein
View articletitled, Preclinical Evaluation of WR-151327: An Orally Active Chemotherapy Protector<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Cellular Pharmacology of N1- and N8-Aziridinyl Analogues of Spermidine1
Zhi-Min Yuan; Merrill J. Egorin; D. Marc Rosen; Marc A. Simon; Patrick S. Callery
View articletitled, Cellular Pharmacology of N<sup>1</sup>- and N<sup>8</sup>-Aziridinyl Analogues of Spermidine<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Quantitative and Qualitative Aspects of Topoisomerase I and IIα and β in Untreated and Platinum/Cyclophosphamide Treated Malignant Ovarian Tumors1
Ate G. J. van der Zee; Steven de Jong; W. Nicol Keith; Harrie Hollema; Henk Boonstra; Elisabeth G. E. de Vries
View articletitled, Quantitative and Qualitative Aspects of Topoisomerase I and IIα and β in Untreated and Platinum/Cyclophosphamide Treated Malignant Ovarian Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Altered Subcellular Distribution of Topoisomerase IIα in a Drug-resistant Human Small Cell Lung Cancer Cell Line1
Pamela W. Feldhoff; Shelagh E. L. Mirski; Susan P. C. Cole; Daniel M. Sullivan
View articletitled, Altered Subcellular Distribution of Topoisomerase IIα in a Drug-resistant Human Small Cell Lung Cancer Cell Line<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Effect of Human Natural Killer Cells on the Metastatic Growth of Human Melanoma Xenografts in Mice with Severe Combined Immunodeficiency1
Laurie L. Hill; Bice Perussia; Peter A. McCue; Robert Korngold
View articletitled, Effect of Human Natural Killer Cells on the Metastatic Growth of Human Melanoma Xenografts in Mice with Severe Combined Immunodeficiency<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Cytotoxic Efficacy of 9-Nitrocamptothecin in the Treatment of Human Malignant Melanoma Cells in Vitro1
Panayotis Pantazis; Janet A. Early; John T. Mendoza; Albert R. DeJesus; Beppino C. Giovanella
View articletitled, Cytotoxic Efficacy of 9-Nitrocamptothecin in the Treatment of Human Malignant Melanoma Cells <em>in Vitro</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Human Interleukin-3 Stimulates a Phosphatidylcholine Specific Phospholipase C and Protein Kinase C Translocation1
Padmini Rao; R. Allan Mufson
View articletitled, Human Interleukin-3 Stimulates a Phosphatidylcholine Specific Phospholipase C and Protein Kinase C Translocation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Two Molecular Pathways to Transitional Cell Carcinoma of the Bladder1
Charles H. Spruck, III; Petra F. Ohneseit; Mirella Gonzalez-Zulueta; David Esrig; Noriomi Miyao; Yvonne C. Tsai; Seth P. Lerner; Christoph Schmütte; Allen S. Yang; Richard Cote; Louis Dubeau; Peter W. Nichols; Gregers G. Hermann; Kenneth Steven; Thomas Horn; Donald G. Skinner; Peter A. Jones
View articletitled, Two Molecular Pathways to Transitional Cell Carcinoma of the Bladder<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Inverse Correlation between Expression of Inducible Nitric Oxide Synthase Activity and Production of Metastasis in K-1735 Murine Melanoma Cells1
Zhongyun Dong; Alexander H. Staroselsky; Xiaoxia Qi; Keping Xie; Isaiah J. Fidler
View articletitled, Inverse Correlation between Expression of Inducible Nitric Oxide Synthase Activity and Production of Metastasis in K-1735 Murine Melanoma Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Molecular Abnormalities of mdm2 and p53 Genes in Adult Soft Tissue Sarcomas1
Carlos Cordon-Cardo; Esther Latres; Marija Drobnjak; Maria R. Oliva; Daphna Pollack; James M. Woodruff; Vincent Marechal; Jiandong Chen; Murray F. Brennan; Arnold J. Levine
View articletitled, Molecular Abnormalities of <em>mdm</em>2 and <em>p53</em> Genes in Adult Soft Tissue Sarcomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Demonstration and Characterization of the Angiogenic Properties of Cervical Dysplasia
Karen K. Smith-McCune; Noel Weidner
View articletitled, Demonstration and Characterization of the Angiogenic Properties of Cervical Dysplasia
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Antiproliferative Effects of 1,25-Dihydroxyvitamin D3 on Primary Cultures of Human Prostatic Cells1
Donna M. Peehl; Roman J. Skowronski; Gordon K. Leung; Stephen T. Wong; Thomas A. Stamey; David Feldman
View articletitled, Antiproliferative Effects of 1,25-Dihydroxyvitamin D<sub>3</sub> on Primary Cultures of Human Prostatic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Proliferation Kinetics of Recruited Cells in a Mouse Mammary Carcinoma1
Alan Pollack; Nicholas H. A. Terry; R. Allen White; Shilong Cao; Marvin L. Meistrich; Luka Milas
View articletitled, Proliferation Kinetics of Recruited Cells in a Mouse Mammary Carcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Bombesin Receptors in a Human Duodenal Tumor Cell Line: Binding Properties and Function1
Barbara Y. Williams; Agnes Schonbrunn
View articletitled, Bombesin Receptors in a Human Duodenal Tumor Cell Line: Binding Properties and Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Resistance to TNF-α and Adriamycin in the Human Breast Cancer MCF-7 Cell Line: Relationship to MDR1, MnSOD, and TNF Gene Expression1
Abdelmajid Zyad; Jean Bénard; Thomas Tursz; Robert Clarke; Salem Chouaib
View articletitled, Resistance to TNF-α and Adriamycin in the Human Breast Cancer MCF-7 Cell Line: Relationship to <em>MDR1</em>, MnSOD, and TNF Gene Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Reduced Malignancy of ras-transformed NIH 3T3 Cells Expressing Antisense Osteopontin RNA1
Elke I. Behrend; Ann Marie Craig; Sylvia M. Wilson; David T. Denhardt; Ann F. Chambers
View articletitled, Reduced Malignancy of <em>ras</em>-transformed NIH 3T3 Cells Expressing Antisense Osteopontin RNA<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Selective Down-Regulation of Integrin Receptors in Spheroids of Squamous Cell Carcinoma1
Nahid S. Waleh; John Gallo; Tandora D. Grant; Brian J. Murphy; Randall H. Kramer; Robert M. Sutherland
View articletitled, Selective Down-Regulation of Integrin Receptors in Spheroids of Squamous Cell Carcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Inhibition of the Soluble and the Tumor Cell Receptor-bound Plasmin by Urinary Trypsin Inhibitor and Subsequent Effects on Tumor Cell Invasion and Metastasis1
Hiroshi Kobayashi; Hiromitsu Shinohara; Kinya Takeuchi; Mariko Itoh; Michio Fujie; Motoo Saitoh; Toshihiko Terao
View articletitled, Inhibition of the Soluble and the Tumor Cell Receptor-bound Plasmin by Urinary Trypsin Inhibitor and Subsequent Effects on Tumor Cell Invasion and Metastasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Parathyroid Hormone-like Protein: Alternative Messenger RNA Splicing Pathways in Human Cancer Cell Lines1
David W. Brandt; William Wachsman; Leonard J. Deftos
View articletitled, Parathyroid Hormone-like Protein: Alternative Messenger RNA Splicing Pathways in Human Cancer Cell Lines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Second International Cancer Chemoprevention Conference1
View articletitled, Second International Cancer Chemoprevention Conference<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>
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Announcements
View articletitled, Announcements
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Calendar of Events
View articletitled, Calendar of Events
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Erratum
View articletitled, Erratum
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