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Volume 53, Issue 17

1 September 1993

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Front Matter
Table of Contents
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Editorial Board

ISSN 0008-5472

EISSN 1538-7445

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Articles

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Articles

Increased Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor and Transforming Growth Factor β1 Levels during Monoterpene-induced Regression of Mammary Tumors ¹

Randy L. Jirtle; Jill D. Haag; Eric A. Ariazi; Michael N. Gould

Abstract

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Heterogeneity in MLL/AF-4 Fusion Messenger RNA Detected by the Polymerase Chain Reaction in t(4;11) Acute Leukemia ¹

Joanne M. Hilden; Chien-Shing Chen; Roderick Moore; Joy Frestedt; John H. Kersey

Abstract

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The Effect of Stem Cell Factor on Irradiated Human Bone Marrow ¹

Bryan R. Leigh; Steven L. Hancock; Susan J. Knox

Abstract

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Use of Tissue-specific Expression of the Herpes Simplex Virus Thymidine Kinase Gene to Inhibit Growth of Established Murine Melanomas following Direct Intratumoral Injection of DNA

Richard G. Vile; Ian R. Hart

Abstract

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Association of Putative Origins of Replication with the Nuclear Matrix in Normal Human Fibroblasts ¹

Bruna P. Brylawski; Gregory J. Tsongalis; Marila Cordeiro-Stone; W. Todd May; Laurey D. Comeau; David G. Kaufman

Abstract

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Homozygous Deletion and Frequent Allelic Loss of Chromosome 8p22 Loci in Human Prostate Cancer ¹

G. Steven Bova; Bob S. Carter; Marion J. G. Bussemakers; Mitsuru Emi; Yoshiyuki Fujiwara; Natasha Kyprianou; Stephen C. Jacobs; John C. Robinson; Jonathan I. Epstein; Patrick C. Walsh; William B. Isaacs

Abstract

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Transplacental Carcinogenicity of Cisplatin: Initiation of Skin Tumors and Induction of Other Preneoplastic and Neoplastic Lesions in SENCAR Mice ¹

Bhalchandra A. Diwan; Lucy M. Anderson; Sabine Rehm; Jerry M. Rice

Abstract

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Alternatively Spliced Glucocorticoid Receptor Messenger RNAs in Glucocorticoid-resistant Human Multiple Myeloma Cells ¹

Pamela A. Moalli; Shafali Pillay; Nancy L. Krett; Steven T. Rosen

Abstract

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Radiation-induced Transforming Growth Factor β and Subsequent Extracellular Matrix Reorganization in Murine Mammary Gland ¹

M. H. Barcellos-Hoff

Abstract

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Resistance to Aflatoxin B₁ Is Associated with the Expression of a Novel Aldo-Keto Reductase Which Has Catalytic Activity towards a Cytotoxic Aldehyde-containing Metabolite of the Toxin ¹

John D. Hayes; David J. Judah; Gordon E. Neal

Abstract

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Repair of O⁶-Methylguanine and O⁴-Methylthymidine in F344 Rat Liver following Treatment with 1,2-Dimethylhydrazine and O⁶-Benzylguanine

Susan M. O'Toole; Anthony E. Pegg; James A. Swenberg

Abstract

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N-Acetylglucosaminyltransferase III and V Messenger RNA Levels in LEC Rats during Hepatocarcinogenesis

Eiji Miyoshi; Atsushi Nishikawa; Yoshito Ihara; Jianguo Gu; Toshihiro Sugiyama; Norio Hayashi; Hideyuki Fusamoto; Takenobu Kamada; Naoyuki Taniguchi

Abstract

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Chemopreventive Effects of Dietary d,l-α-Difluoromethylornithine, an Ornithine Decarboxylase Inhibitor, on Initiation and Postinitiation Stages of Diethylnitrosamine-induced Rat Hepatocarcinogenesis

Toshihiro Kojima; Takuji Tanaka; Toshihiko Kawamori; Akira Hara; Hideki Mori

Abstract

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Chemoprevention of Colon Carcinogenesis by the Natural Product of a Simple Phenolic Compound Protocatechuic Acid: Suppressing Effects on Tumor Development and Biomarkers Expression of Colon Tumorigenesis ¹

Takuji Tanaka; Toshihiro Kojima; Masumi Suzui; Hideki Mori

Abstract

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Inhibitory Effect of Bifidobacterium longum on Colon, Mammary, and Liver Carcinogenesis Induced by 2-Amino-3-methylimidazo[4,5-f]quinoline, a Food Mutagen ¹

Bandaru S. Reddy; Abraham Rivenson

Abstract

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Two-Year Carcinogenicity Study of Tamoxifen in Alderley Park Wistar-derived Rats

Peter Greaves; Ranjit Goonetilleke; Gary Nunn; John Topham; Terry Orton

Abstract

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Stimulation of Growth of Azaserine-induced Putative Preneoplastic Lesions in Rat Pancreas Is Mediated Specifically by Way of Cholecystokinin-A Receptors ¹

Stephen P. Povoski; Weigong Zhou; Daniel S. Longnecker; Bill D. Roebuck; Richard H. Bell, Jr.

Abstract

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Phase I Trial of a 90-Minute Infusion of the Fusion Toxin DAB₄₈₆IL-2 in Hematological Cancers ¹

C. F. LeMaistre; Fiona E. Craig; Carole Meneghetti; Becky McMullin; Karen Parker; James Reuben; David H. Boldt; Michael Rosenblum; Thasia Woodworth

Abstract

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Selective Biological Response by Target Organs (Intestine, Kidney, and Bone) to 1,25-Dihydroxyvitamin D₃ and Two Analogues ¹

Anthony W. Norman; Igor N. Sergeev; June E. Bishop; William H. Okamura

Abstract

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Control of HLA-DR Antigen Expression by γ-Interferon: Separate Signal Transduction Mechanisms in Malignant and Nonmalignant Human Thyroid Cells

Nitza Lahat; Esther Sobel; Zaki Kraiem

Abstract

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Interaction of a Polyamine Analogue, 1,19-bis-(Ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4), with DNA and Effect on Growth, Survival, and Polyamine Levels in Seven Human Brain Tumor Cell Lines ¹

Hirak S. Basu; Malgorzata Pellarin; Burt G. Feuerstein; Akira Shirahata; Keijiro Samejima; Dennis F. Deen; Laurence J. Marton

Abstract

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Site-specific Prodrug Activation by Antibody-β-Lactamase Conjugates: Regression and Long-Term Growth Inhibition of Human Colon Carcinoma Xenograft Models

Damon L. Meyer; Louis N. Jungheim; Kevin L. Law; Stephen D. Mikolajczyk; Timothy A. Shepherd; Daniel G. Mackensen; Stephen L. Briggs; James J. Starling

Abstract

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Arrest of Human Lung Tumor Xenograft Growth in Severe Combined Immunodeficient Mice Using Doxorubicin Encapsulated in Sterically Stabilized Liposomes ¹

Scott S. Williams; Thomas R. Alosco; Eric Mayhew; Danilo D. Lasic; Frank J. Martin; Richard B. Bankert

Abstract

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Neuroblastoma Sensitivity to Growth Inhibition by Deferrioxamine: Evidence for a Block in G₁ Phase of the Cell Cycle ¹

Chaya Brodie; Gamini Siriwardana; Joseph Lucas; Rhoda Schleicher; Nao Terada; Agota Szepesi; Erwin Gelfand; Paul Seligman

Abstract

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Specific Proteolytic Cleavage of Poly(ADP-ribose) Polymerase: An Early Marker of Chemotherapy-induced Apoptosis ¹

Scott H. Kaufmann; Serge Desnoyers; Yvonne Ottaviano; Nancy E. Davidson; Guy G. Poirier

Abstract

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In Vitro and in Vivo Effect of Doxorubicin Combined with Liposome-encapsulated Muramyl Tripeptide on Canine Monocyte Activation ¹

Fushun Shi; E. Gregory MacEwen; Ilene D. Kurzman

Abstract

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Unusual Oxygen Concentration Dependence of Toxicity of SR-4233, a Hypoxic Cell Toxin ¹

C. J. Koch

Abstract

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Amphibolic Drug Combinations: The Design of Selective Antimetabolite Protocols Based upon the Kinetic Properties of Multienzyme Systems

Robert C. Jackson

Abstract

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Inhibition by Oxonic Acid of Gastrointestinal Toxicity of 5-Fluorouracil without Loss of Its Antitumor Activity in Rats

Tetsuhiko Shirasaka; Yuji Shimamoto; Masakazu Fukushima

Abstract

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Interleukin-1β Induces Interleukin-1 Receptor Antagonist and Tumor Necrosis Factor Binding Protein in Humans ¹

Mario J. Bargetzi; Mikael Lantz; Christopher G. Smith; Frank M. Torti; Inge Olsson; Stephen P. Eisenberg; H. Fletcher Starnes, Jr.

Abstract

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Killing of Skin-derived Tumor Cells by Mouse Dendritic Epidermal T-Cells ¹

Marek J. Kaminski; Ponciano D. Cruz, Jr.; Paul R. Bergstresser; Akira Takashima

Abstract

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Tumor-specific Lysis of Human Renal Cell Carcinomas by Tumor-infiltrating Lymphocytes: Modulation of Recognition through Retroviral Transduction of TumorCells with Interleukin 2 Complementary DNA and Exogenous α Interferon Treatment ¹

Dolores J. Schendel; Bernd Gansbacher

Abstract

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Highly Specific in Vivo Tumor Targeting by Monovalent and Divalent Forms of 741F8 Anti-c-erbB-2 Single-Chain Fv ¹

Gregory P. Adams; John E. McCartney; Mei-Sheng Tai; Hermann Oppermann; James S. Huston; Walter F. Stafford, III; Michael A. Bookman; Irwin Fand; L. L. Houston; Louis M. Weiner

Abstract

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Genotypic Characterization of Prostatic Carcinomas: A Combined Cytogenetic, Flow Cytometry, and in Situ DNA Hybridization Study

Thomas Breitkreuz; Konstantinos Romanakis; Steffi Lutz; Gerhard Seitz; Helmut Bonkhoff; Gerhard Unteregger; Thomas Zwergel; Klaus Dieter Zang; Bernd Wullich

Abstract

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Transforming Growth Factor-β1 Induces Transforming Growth Factor-α Promoter Activity and Transforming Growth Factor-α Secretion in the Human Colon Adenocarcinoma Cell Line FET ¹

Mark J. Lynch; Lenore Pelosi; Joan M. Carboni; June Merwin; Kevin Coleman; Richard R. C. Wang; Pin-Fang M. Lin; Diane L. Henry; Michael G. Brattain

Abstract

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Gastric and Hepatocellular Carcinomas Do Not Overexpress the Same Ribosomal Protein Messenger RNAs as Colonic Carcinoma ¹

Graham F. Barnard; Raymond J. Staniunas; Masaki Mori; Mark Puder; Milburn J. Jessup; Glenn D. Steele, Jr.; Lan Bo Chen

Abstract

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Mutation of the p53 Gene in Neuroblastoma and Its Relationship with N-myc Amplification ¹

Jun Imamura; Claus R. Bartram; Frank Berthold; Dieter Harms; Haruhiko Nakamura; H. Phillip Koeffler

Abstract

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Cloning and Expression of Mutant Glucocorticoid Receptors from Glucocorticoid-sensitive and -resistant Human Leukemic Cells ¹

Joan H. Powers; Andrew G. Hillmann; Delia C. Tang; Jeffrey M. Harmon

Abstract

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Role of Chromosome 9 in Human Bladder Cancer ¹

Noriomi Miyao; Yvonne C. Tsai; Seth P. Lerner; Aria F. Olumi; Charles H. Spruck, III; Mirella Gonzalez-Zulueta; Peter W. Nichols; Donald G. Skinner; Peter A. Jones

Abstract

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Clonal Analysis of Fibroadenoma and Phyllodes Tumor of the Breast

Shinzaburo Noguchi; Kazuyoshi Motomura; Hideo Inaji; Shingi Imaoka; Hiroki Koyama

Abstract

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Differential Growth Factor Production, Secretion, and Response by High and Low Metastatic Variants of B16BL6 Melanoma ¹

Vincent D. Blanckaert; Margaret E. Schelling; Catherine A. Elstad; Gary G. Meadows

Abstract

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Altered Glycosylation of the MUC-1 Protein Core Contributes to the Colon Carcinoma-associated Increase of Mucin-bound Sialyl-Lewis^x Expression ¹

Christoph Hanski; Kristin Drechsler; Franz-Georg Hanisch; John Sheehan; Monika Manske; Dieter Ogorek; Enno Klussmann; Marie-Luise Hanski; Monika Blank; Pei-Xiang Xing; Ian F. C. McKenzie; Peter L. Devine; Ernst-Otto Riecken

Abstract

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Cell Lines from grc Congenic Strains of Rats Having Different Susceptibilities to Chemical Carcinogens ¹

Di Lu; Heinz W. Kunz; Mona F. Melhem; Thomas J. Gill, III

Abstract

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Identification of a New Interferon-α-inducible Gene (p27) on Human Chromosome 14q32 and Its Expression in Breast Carcinoma ¹

Ulla B. Rasmussen; Catherine Wolf; Marie-Geneviève Mattei; Marie-Pierre Chenard; Jean-Pierre Bellocq; Pierre Chambon; Marie-Christine Rio; Paul Basset

Abstract

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Interleukin 1α Acts as an Autocrine Growth Stimulator for Human Gastric Carcinoma Cells ¹

Reiko Ito; Yasuhiko Kitadai; Eikai Kyo; Hiroshi Yokozaki; Wataru Yasui; Uki Yamashita; Hiromasa Nikai; Eiichi Tahara

Abstract

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Correspondence re: R. Peto et al., Effects on 4080 Rats of Chronic Ingestion of N-Nitrosodiethylamine or N-Nitrosodimethylamine: A Detailed Dose-Response Study. Cancer Res., 51: 6415–6451, 1991, and K. S. Crump et al., Fundamental Carcinogenic Processes and Their Implications for Low Dose Risk Assessment. Cancer Res., 36: 2973–2979, 1976.

Gerhard Stöhrer

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Correspondence re: R. Peto et al., Effects on 4080 Rats of Chronic Ingestion of N-Nitrosodiethylamine or N-Nitrosodimethylamine: A Detailed Dose-Response Study. Cancer Res., 51: 6415–6451, 1991, and K. S. Crump et al., Fundamental Carcinogenic Processes and Their Implications for Low Dose Risk Assessment. Cancer Res., 36: 2973–2979, 1976. — Reply

Richard Peto; Richard Gray

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