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Volume 48, Issue 6

15 March 1988

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Front Matter
Table of Contents
Back Matter
Editorial Board

ISSN 0008-5472

EISSN 1538-7445

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Articles

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Articles

Changing Concepts in Cancer Prevention: Limitations and Implications for Future Research in Environmental Carcinogenesis

John Higginson

Abstract

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Epoxide-metabolizing Enzymes in Mammary Gland and Liver from BALB/c Mice and Effects of Inducers on Enzyme Activity ¹

Marilyn H. Silva; Roger N. Wixtrom; Bruce D. Hammock

Abstract

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Effector Mechanism of Tumor Immunity in Murine Plasmacytoma ¹

Yi-Hsiang Chen; Alan B. Anderson

Abstract

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Production of Protein-associated DNA Breaks by 10-[Diethylaminopropylamino]-6-methyl-5H-pyrido[3′,4′:4,5]pyrrolo[2,3-g]isoquinoline in Cultured L1210 Cells and in Isolated Nuclei: Comparison with Other Topoisomerase II Inhibitors

Veronique Pierson; Alain Pierre; Yves Pommier; Pierre Gros

Abstract

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Augmentation of Murine Natural Killer Cell Activity by Swainsonine, a New Antimetastatic Immunomodulator ¹

Martin J. Humphries; Kazue Matsumoto; Sandra L. White; Russell J. Molyneux; Kenneth Olden

Abstract

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Identification of Cell Surface Cathepsin B-like Activity on Murine Melanomas and Fibrosarcomas: Modulation by Butanol Extraction ¹

Z. Keren; S. J. LeGrue

Abstract

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Phenotype of Syngeneic Tumor-specific Cytotoxic T-Lymphocytes and Requirements for Their in Vitro Generation from Tumor-bearing Host and Immune Spleens ¹

Harry D. Bear; Brian M. Susskind; Karen A. Close; Sandra K. Barrett

Abstract

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Variant Forms of Rat Epidermal Growth Factor Present in the Urine of Nude Rats Bearing Human Tumors

W. Robert Hudgins; David N. Orth; Kurt Stromberg

Abstract

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Correlative Study on Expression of CA 19-9 and DU-PAN-2 in Tumor Tissue and in Serum of Pancreatic Cancer Patients ¹

Hideaki Takasaki; Eiji Uchida; Margaret A. Tempero; David A. Burnett; Richard S. Metzgar; Parviz M. Pour

Abstract

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Effects of Bombesin on Growth of Human Small Cell Lung Carcinoma in Vivo¹

Robert W. Alexander; James R. Upp, Jr.; Graeme J. Poston; Vicram Gupta; Courtney M. Townsend, Jr.; James C. Thompson

Abstract

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Nucleoside Restoration of Heat Resistance and Suppression of Glucose-regulated Protein Synthesis by Glucose-deprived L929 Cells ¹

Karl W. Lanks; Jian-Ping Gao; Efthimios J. Kasambalides

Abstract

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Radiohalogenation of a Monoclonal Antibody Using an N-Succinimidyl 3-(Tri-n-butylstannyl)benzoate Intermediate ¹

Michael R. Zalutsky; Acharan S. Narula

Abstract

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Involvement of Soybean Agglutinin Binding Cells in the Lymphatic Metastasis of the R3230AC Rat Mammary Adenocarcinoma ¹

Nicole D. Buckley; Svein A. Carlsen

Abstract

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Enhancement of Metastatic Capacity of Fibroblast-Tumor Cell Interaction in Mice ¹

Hajime Tanaka; Yoichi Mori; Hiroko Ishii; Hitoshi Akedo

Abstract

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Functional Role of Platelets in Experimental Metastasis Studied with Cloned Murine Fibrosarcoma Cell Variants ¹

Meera Mahalingam; Kenneth E. Ugen; Kuo-Jang Kao; Paul A. Klein

Abstract

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Influence of Retinoids on Growth and Metastasis of Hamster Melanoma in Athymic Mice ¹

Rosemary L. Schleicher; Richard C. Moon; Minu K. Patel; Craig W. Beattie

Abstract

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Specificity, Schedule, and Proliferation Dependence of Infused l-Histidinol after 5-Fluorouracil in Mice ¹

Mark B. Edelstein; Lance K. Heilbrun

Abstract

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Effect of Galactose on Systemic Hemodynamics and Blood Flow Rate in Normal and Tumor Tissues in Rats ¹

Donald J. DiPette; Kimberly A. Ward; Rakesh K. Jain; Nancy E. Kerr; Kathy Schwarzenberger

Abstract

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Cytotoxicity, Uptake, Polyglutamate Formation, and Antileukemic Effects of 8-Deaza Analogues of Methotrexate and Aminopterin in Mice ¹

Michael Kuehl; Diana I. Brixner; Arthur D. Broom; Thomas L. Avery; Raymond L. Blakley

Abstract

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Specific Expression of a Myeloid-associated CMP-NeuAc:Galβ1→3GalNAcα-R α2→3-Sialyltransferase and the Sialyl-X Determinant in Myeloid Human-Mouse Cell Hybrids Containing Human Chromosome 11

Hans T. de Heij; Pedro A. T. Tetteroo; Ad H. M. Geurts van Kessel; Ellen Schoenmaker; Frans J. Visser; Dirk H. van den Eijnden

Abstract

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Effects of 1-β-d-Arabinofuranosylcytosine Incorporation on Elongation of Specific DNA Sequences by DNA Polymerase β ¹

Y. Ohno; D. Spriggs; A. Matsukage; T. Ohno; D. Kufe

Abstract

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Metabolism of N-Nitrosodialkylamines by Human Liver Microsomes ¹

Jeong-Sook H. Yoo; F. Peter Guengerich; Chung S. Yang

Abstract

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Purification and Composition of a Novel Gastrointestinal Tumor-associated Glycoprotein Expressing Sialylated Lacto-N-fucopentaose II (CA 19-9)

Thomas L. Klug; Norman C. LeDonne; Terrance F. Greber; Vincent R. Zurawski, Jr.

Abstract

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Detection of Patients with Cancer by Monoclonal Antibody Directed to Lactoneotetraosylceramide (Paragloboside)

Akio Myoga; Takao Taki; Kenji Arai; Kiyoshi Sekiguchi; Isao Ikeda; Kunio Kurata; Makoto Matsumoto

Abstract

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Sporadic Amplification of the HER2/neu Protooncogene in Adenocarcinomas of Various Tissues ¹

M. Tal; M. Wetzler; Z. Josefberg; A. Deutch; M. Gutman; D. Assaf; R. Kris; Y. Shiloh; D. Givol; J. Schlessinger

Abstract

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Potentiation of Nitrosourea Cytotoxicity in Human Leukemic Cells by Inactivation of O⁶-Alkylguanine-DNA Alkyltransferase ¹

Stanton L. Gerson; Joan E. Trey; Kathleen Miller

Abstract

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Effects of Phosphatidylethanolamine and Phosphatidylcholine in Membrane Phospholipid on Binding of Phorbol Ester in Rat Mammary Carcinoma Cells ¹

Tamiko Kano-Sueoka; David M. King

Abstract

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Carcinogenicity of Hydroxyalkylnitrosamines in F344 Rats: Contrasting Behavior of β- and γ-Hydroxylated Nitrosamines ¹

Steven R. Koepke; Donald R. Creasia; Gary L. Knutsen; Christopher J. Michejda

Abstract

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Alkylation of DNA in Rats by N-Nitrosomethyl-(2-hydroxyethyl)amine: Dose Response and Persistence of the Alkylated Lesions in Vivo¹

Steven R. Koepke; Marilyn B. Kroeger-Koepke; William Bosan; Barbara J. Thomas; W. Gregory Alvord; Christopher J. Michejda

Abstract

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Modification of pH of Normal and Malignant Mouse Tissue by Hydralazine and Glucose, with and without Breathing of 5% CO₂ and 95% Air ¹

Chitose Tobari; Ine Van Kersen; George M. Hahn

Abstract

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Effects of Hematopoietic Suppressor Molecules on the in Vitro Proliferation of Purified Murine Granulocyte-Macrophage Progenitor Cells ¹

Douglas E. Williams; Scott Cooper; Hal E. Broxmeyer

Abstract

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Contribution by Host Tissues to Circulating Glutamine in Mice Inoculated with Ehrlich Ascites Tumor Cells ¹

Ana R. Quesada; Miguel A. Medina; Javier Márquez; Francisca M. Sánchez-Jiménez; Ignacio Núñez de Castro

Abstract

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Alterations in Whole Body, Muscle, Liver, and Tumor Tissue Protein Synthesis and Degradation in Novikoff Hepatoma and Yoshida Sarcoma Tumor Growth Studied in Vivo¹

John A. Tayek; George L. Blackburn; Bruce R. Bistrian

Abstract

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Influence of Aflatoxin B₁ Intoxication on Duck Livers with Duck Hepatitis B Virus Infection ¹

Toshikazu Uchida; Koyu Suzuki; Mariko Esumi; Masayuki Arii; Toshio Shikata

Abstract

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Reversible Induction of Anchorage Independent Growth from Normal Mouse Epidermal Keratinocytes, MSK-C3H-NU, in Soft Agar Medium by 12-O-Tetradecanoylphorbol-13-acetate and Epidermal Growth Factor

Katsuhiko Indo; Takamasa Matsuoka; Keiji Nakasho; Iwao Funahashi; Hideki Miyaji

Abstract

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A New Mucin-associated Oncofetal Antigen, a Marker of Early Carcinogenesis in Rat Colon ¹

Catherine Decaens; Rodolphe Gautier; Jacques Bara; Nagib Daher; Jacques Le Pendu; Pierre Burtin

Abstract

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Multiparametric Study (SAMBA 200) of Estrogen Receptor Immunocytochemical Assay in 400 Human Breast Carcinomas: Analysis of Estrogen Receptor Distribution Heterogeneity in Tissues and Correlations with Dextran Coated Charcoal Assays and Morphological Data ¹

Colette Charpin; Pierre Marie Martin; Bénédicte DeVictor; Marie Noelle Lavaut; Marie Christine Habib; Lucile Andrac; Maurice Toga

Abstract

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Reversal of Transformed Phenotypes by Herbimycin A in src Oncogene Expressed Rat Fibroblasts ¹

Yuko Murakami; Satoshi Mizuno; Makoto Hori; Yoshimasa Uehara

Abstract

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Effect of Cimetidine on Inhibition by Tetragastrin of Carcinogenesis Induced by N-Methyl-N′-nitro-N-nitrosoguanidine in Wistar Rats

Masaharu Tatsuta; Hiroyasu Iishi; Hisako Yamamura; Miyako Baba; Reiko Yamamoto; Haruo Taniguchi

Abstract

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Growth Modulation of Mouse Keratinocytes by Transforming Growth Factors ¹

Robert J. Coffey, Jr.; Nancy J. Sipes; Charles C. Bascom; Ramona Graves-Deal; Claire Y. Pennington; Bernard E. Weissman; Harold L. Moses

Abstract

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DNA Methylation and Expression of the Rat Pepsinogen Gene in Embryonic, Adult, and Neoplastic Tissues

Masao Ichinose; Kazumasa Miki; Chie Furihata; Masae Tatematsu; Yoshikazu Ichihara; Takeshi Ishihara; Isao Katsura; Kazuhiro Sogawa; Yoshiaki Fujii-Kuriyama; Masao Tanji; Hiroshi Oka; Taijiro Matsushima; Kenji Takahashi

Abstract

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Expression of the c-raf Protooncogene, γ-Glutamyltranspeptidase, and Gap Junction Protein in Rat Liver Neoplasms ¹

David G. Beer; Mark J. Neveu; David L. Paul; Ulf R. Rapp; Henry C. Pitot

Abstract

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Reduction of Potential for Replicative but not Unscheduled DNA Synthesis in Hepatocytes Isolated from Aged as Compared to Young Rats ¹

Norimasa Sawada; Takatoshi Ishikawa

Abstract

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Role of Chromosome Loss in ras/myc-induced Syrian Hamster Tumors

Mitsuo Oshimura; Minoru Koi; Nobuyoshi Ozawa; Osamu Sugawara; Patricia W. Lamb; J. Carl Barrett

Abstract

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Coexpression of Neuronal, Glial, and Major Histocompatibility Complex Class II Antigens on Retinoblastoma Cells

Barbara Detrick; Gerald J. Chader; Merlyn Rodrigues; Athanassios P. Kyritsis; Chi-Chao Chan; John J. Hooks

Abstract

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Synergistic Inhibition of Growth of Breast and Colon Human Cancer Cell Lines by Site-selective Cyclic AMP Analogues

Pierosandro Tagliaferri; Dionyssios Katsaros; Timothy Clair; Shamsia Ally; Giampaolo Tortora; Leonard Neckers; Boanerges Rubalcava; Zahra Parandoosh; Yu-an Chang; Ganapathi R. Revankar; Gerald W. Crabtree; Roland K. Robins; Yoon Sang Cho-Chung

Abstract

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A Case-Control Study of Past History of Nasal Diseases and Maxillary Sinus Cancer in Hokkaido, Japan ¹

Katsuhiro Fukuda; Akira Shibata

Abstract

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Age Distribution of Wilms' Tumor: Report from the National Wilms' Tumor Study ¹

Norman Breslow; J. Bruce Beckwith; Marcia Ciol; Katrina Sharples

Abstract

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Adult Stature and Risk of Cancer ¹

Demetrius Albanes; D. Yvonne Jones; Arthur Schatzkin; Marc S. Micozzi; Philip R. Taylor

Abstract

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Randomized Trial of Combined Modality Therapy with and without Thymosin Fraction V in the Treatment of Small Cell Lung Cancer ¹

Howard I. Scher; Brenda Shank; Robert Chapman; Nancy Geller; Carl Pinsky; Richard Gralla; David Kelsen; George Bosl; Robert Golbey; Gina Petroni; Donna Niedzwiecki; Nael Martini; Robert Heelan; Phyllis Hollander; Basil Hilaris; Herbert Oettgen; Robert E. Wittes

Abstract

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Effect of Low Dose Cyclophosphamide on the Immune System of Cancer Patients: Depletion of CD4+, 2H4+ Suppressor-inducer T-Cells ¹

David Berd; Michael J. Mastrangelo

Abstract

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Circadian Rhythm-varying Plasma Concentration of 5-Fluorouracil during a Five-Day Continuous Venous Infusion at a Constant Rate in Cancer Patients ¹

Emmanuel Petit; Gérard Milano; Francis Lévi; Antoine Thyss; François Bailleul; Maurice Schneider

Abstract

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Metabolites of 5-Fluorouracil in Plasma and Urine, as Monitored by ¹⁹F Nuclear Magnetic Resonance Spectroscopy, for Patients Receiving Chemotherapy with or without Methotrexate Pretreatment ¹

William E. Hull; Rüdiger E. Port; Richard Herrmann; Bärbel Britsch; Werner Kunz

Abstract

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Growth Potential of Human Colorectal Carcinomas in Nude Mice: Association with the Preoperative Serum Concentration of Carcinoembryonic Antigen in Patients ¹

J. M. Jessup; R. Giavazzi; D. Campbell; K. Cleary; K. Morikawa; I. J. Fidler

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