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Volume 48, Issue 15

1 August 1988

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Front Matter
Table of Contents
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Editorial Board

ISSN 0008-5472

EISSN 1538-7445

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Articles

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Articles

The Origins of Human Cancer: Molecular Mechanisms of Carcinogenesis and Their Implications for Cancer Prevention and Treatment—Twenty-seventh G. H. A. Clowes Memorial Award Lecture ¹

I. Bernard Weinstein

Abstract

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Comparative Study of DNA Damage and Repair Induced by Ten N-Nitroso Compounds in Primary Cultures of Human and Rat Hepatocytes ¹

Antonietta Martelli; Luigi Robbiano; Gian Massimo Gazzaniga; Giovanni Brambilla

Abstract

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Increased Levels of DNA Lesions Induced by Leucovorin-5-Fluoropyrimidine in Human Colon Adenocarcinoma ¹

Ulf Lönn; Sigrid Lönn

Abstract

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Glandular Kallikrein in Estrogen-induced Pituitary Tumors: Time Course of Induction and Correlation with Prolactin

Mary Ann Hatala; C. Andrew Powers

Abstract

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Adoptive Immunotherapy by Pantropic Killer Cells Recovered from OK-432-injected Tumor Sites in Mice ¹

Motoo Saito; Masaki Nanjo; Motoyuki Kataoka; Yoichiro Moriya; Yutaka Sugawara; Takeshi Yoshida; Nakao Ishida

Abstract

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Iron Nutrition and Tumor Growth: Decreased Tumor Growth in Iron-deficient Mice ¹

Hie-Won L. Hann; Mark W. Stahlhut; Baruch S. Blumberg

Abstract

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Comparative Developmental and Phenotypic Properties of Altered Hepatocyte Foci and Hepatic Tumors in Rats ¹

Carl Peraino; Bruce A. Carnes; Fred J. Stevens; Everett F. Staffeldt; John J. Russell; Aldona Prapuolenis; Jeanne A. Blomquist; Stan D. Vesselinovitch; Robert R. Maronpot

Abstract

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Selective Accumulation of 3′,5′-Dioctanoyl-5-fluoro-2′-deoxyuridine (FdUrd-C8) and Sustained Release of Its Active Metabolites in VX-2 Rabbit Hepatoma following Intraarterial Administration of FdUrd-C8 Solution in Lipiodol

Takeo Kawaguchi; Shoji Fukushima; Yoshiki Hayashi; Mika Kaneko; Masahiro Nakano

Abstract

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Detection of O⁶-Methyldeoxyguanosine in Human Placental DNA ^{1, 2}

Peter G. Foiles; Lisa M. Miglietta; Shobha A. Akerkar; Richard B. Everson; Stephen S. Hecht

Abstract

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Experimental Chemotherapy of Human Medulloblastoma Cell Lines and Transplantable Xenografts with Bifunctional Alkylating Agents ¹

Henry S. Friedman; O. Michael Colvin; Stephen X. Skapek; Susan M. Ludeman; Gertrude B. Elion; S. Clifford Schold, Jr.; Phillip F. Jacobsen; Lawrence H. Muhlbaier; Darell D. Bigner

Abstract

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Comparison of Combinations of Interferons with Tumor Specific and Nonspecific Monoclonal Antibodies as Therapy for Murine B- and T-Cell Lymphomas ¹

Teresa Y. Basham; Michael A. Palladino; Christopher C. Badger; Irwin D. Bernstein; Ronald Levy; Thomas C. Merigan

Abstract

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Purification of a Low Molecular Weight Factor That Induces Differentiation and Inhibits Growth in Myeloid Leukemia Cells ¹

Kazuyasu Nakaya; Noriko Kumakawa; Hironobu Iinuma; Yasuharu Nakamura

Abstract

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Effect of Cyclophosphamide on the Pathophysiology of RIF-1 Solid Tumors ¹

Paul G. Braunschweiger

Abstract

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Similar, Potent Tumor-promoting Activity of All Isomers of Teleocidins A and B in a Two-Stage Carcinogenesis Experiment on the Skin of CD-1 Mice ¹

Hirota Fujiki; Masami Suganuma; Mitsuo Ninomiya; Shigeru Yoshizawa; Katsumi Yamashita; Shozo Takayama; Yukio Hitotsuyanagi; Shin-ichiro Sakai; Koichi Shudo; Takashi Sugimura

Abstract

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Factors Regulating Activation and DNA Alkylation by 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and Nitrosodimethylamine in Rat Lung and Isolated Lung Cells, and the Relationship to Carcinogenicity

Theodora R. Devereux; Marshall W. Anderson; Steven A. Belinsky

Abstract

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Increased Ornithine Decarboxylase Activity in Cultured Cells Exposed to Low Energy Modulated Microwave Fields and Phorbol Ester Tumor Promoters ¹

Craig V. Byus; K. Kartun; S. Pieper; W. Ross Adey

Abstract

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Induction of Repair Synthesis of DNA in Mammary and Urinary Bladder Epithelial Cells by N-Hydroxy Derivatives of Carcinogenic Arylamines ¹

Ching Y. Wang; Hideyuki Yamada; Kenneth C. Morton; Kim Zukowski; Mei-Sie Lee; Charles M. King

Abstract

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Mechanism of Alteration of Poly(Adenosine Diphosphate-Ribose) Metabolism by Hyperthermia ¹

Göran G. Jonsson; Elaine L. Jacobson; Myron K. Jacobson

Abstract

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Effect of Hyperthermia on Poly(Adenosine Diphosphate-Ribose) Glycohydrolase ¹

Göran G. Jonsson; Luc Menard; Elaine L. Jacobson; Guy G. Poirier; Myron K. Jacobson

Abstract

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Synergistic Cytotoxicity and DNA Strand Break Formation by Bromodeoxyuridine and Bleomycin in Human Tumor Cells ¹

Stephen P. Ackland; Richard L. Schilsky; Michael A. Beckett; Ralph R. Weichselbaum

Abstract

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Important Role of Serotonin in the Antitumor Effects of Recombinant Human Tumor Necrosis Factor-α in Mice

Toshitaka Manda; Fusako Nishigaki; Jo Mori; Kyoichi Shimomura

Abstract

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Comparative Tumorigenicity of 1-Nitropyrene, 1-Nitrosopyrene, and 1-Aminopyrene Administered by Gavage to Sprague-Dawley Rats ¹

Karam El-Bayoumy; Abraham Rivenson; Bruce Johnson; Joann DiBello; Patricia Little; Stephen S. Hecht

Abstract

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Oxidative Metabolism of 1-Nitropyrene by Rabbit Liver Microsomes and Purified Microsomal Cytochrome P-450 Isozymes ¹

Paul C. Howard; Kimberly A. Reed; Dennis R. Koop

Abstract

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Regulatory Effects of Cell Density on the Binding of Transforming Growth Factor β, Epidermal Growth Factor, Platelet-derived Growth Factor, and Fibroblast Growth Factor ¹

Angie Rizzino; Peter Kazakoff; Eric Ruff; Charles Kuszynski; John Nebelsick

Abstract

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Effect of Thymidine on Uptake, DNA Alkylation, and DNA Repair in L1210 Cells Treated with 1,3-Bis(2-chloroethyl)-1-nitrosourea or 3′-[3-(2-Chloroethyl)-3-nitrosoureido]-3′-deoxythymidine ¹

E. Michael August; William H. Prusoff

Abstract

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Influence of Dietary Fat, Caloric Restriction, and Voluntary Exercise on N-Nitrosomethylurea-induced Mammary Tumorigenesis in Rats ¹

Leonard A. Cohen; Keewhan Choi; Chung-Xiou Wang

Abstract

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Production of Bone-resorbing Activity Corresponding to Interleukin-1α by Adult T-Cell Leukemia Cells in Humans ¹

Fumihiko Shirakawa; Uki Yamashita; Yoshiya Tanaka; Kennichi Watanaba; Kanji Sato; Joji Haratake; Takashi Fujihira; Susumu Oda; Sumiya Eto

Abstract

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Flow Cytometric Analysis by Bromodeoxyuridine/DNA Assay of Cell Cycle Perturbation of Methotrexate-treated Mouse L1210 Leukemia Cells ¹

Masahito Tsurusawa; Makoto Niwa; Naoyuki Katano; Takeo Fujimoto

Abstract

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Preclinical Pharmacology of Arabinosyl-5-azacytidine in Nonhuman Primates

Richard L. Heideman; Frank M. Balis; Cynthia McCully; David G. Poplack

Abstract

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Biochemical Characterization of Tyrosine Kinase and Phosphotyrosine Phosphatase Activities of HL-60 Leukemia Cells ¹

David A. Frank; Alan C. Sartorelli

Abstract

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Indistinguishable Patterns of Protooncogene Expression in Two Distinct but Closely Related Tumors: Ewing's Sarcoma and Neuroepithelioma

Catherine McKeon; Carol J. Thiele; Robert A. Ross; Michael Kwan; Timothy J. Triche; James S. Miser; Mark A. Israel

Abstract

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Metastatic Potential Prediction by a Visual Grading System of Cell Motility: Prospective Validation in the Dunning R-3327 Prostatic Adenocarcinoma Model ¹

James L. Mohler; Alan W. Partin; John T. Isaacs; Donald S. Coffey

Abstract

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Tumor-associated Membrane Sialoglycoprotein on Human Small Cell Lung Carcinoma Identified by the IgG2a Monoclonal Antibody SWA20 ¹

Robert Waibel; Carl J. O'Hara; Alan Smith; Rolf A. Stahel

Abstract

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Localization and Imaging of Radiolabeled Monoclonal Antibodies against Colorectal Carcinoma in Tumor-bearing Nude Mice ¹

Donald Buchsbaum; Ricardo Lloyd; Jack Juni; Ira Wollner; Pamela Brubaker; David Hanna; Judith Spicker; Felissa Burns; Zenon Steplewski; David Colcher; Jeffrey Schlom; Franz Buchegger; Jean-Pierre Mach

Abstract

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In Situ Hybridization Analysis of Acquisition and Loss of the Human Multidrug-Resistance Gene

Ding-Wu Shen; Ira Pastan; Michael M. Gottesman

Abstract

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Genetic Instability and the Development of Steroid Hormone Insensitivity in Cultured T 47D Human Breast Cancer Cells ¹

Roger R. Reddel; Ian E. Alexander; Masafumi Koga; John Shine; Robert L. Sutherland

Abstract

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Preclinical Studies on the Pharmacokinetic Properties of Human Monoclonal Antibodies to Colorectal Cancer and Their Use for Detection of Tumors

Richard P. McCabe; Leona C. Peters; Martin V. Haspel; Nicholas Pomato; Jorge A. Carrasquillo; Michael G. Hanna, Jr.

Abstract

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Partial Prevention of Procarbazine Induced Germinal Cell Aplasia in Rats by Sequential GnRH Antagonist and Testosterone Administration ¹

L. M. Pogach; Y. Lee; S. Gould; W. Giglio; H. F. S. Huang

Abstract

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Immunoglobulin G3 Monoclonal Antibody Directed to Tn Antigen (Tumor-associated α-N-Acetylgalactosaminyl Epitope) That Does Not Cross-React with Blood Group A Antigen ¹

Hélio K. Takahashi; Rikiya Metoki; Sen-itiroh Hakomori

Abstract

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Multiparametric Evaluation (SAMBA) of Growth Fraction (Monoclonal Ki67) in Breast Carcinoma Tissue Sections ¹

Colette Charpin; Lucile Andrac; Hélène Vacheret; Marie Christine Habib; Bénédicte Devictor; Marie Noëlle Lavaut; Maurice Toga

Abstract

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In Vivo and in Vitro Enhanced Antitumor Effects by Pentoxifylline in Human Cancer Cells Treated with Thiotepa ¹

Howard J. Fingert; Anthony T. Pu; Zuying Chen; Paul B. Googe; Michael C. Alley; Arthur B. Pardee

Abstract

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Extrapulmonary, Tissue-specific Metastasis Formation in Nude Mice Injected with FEMX-I Human Melanoma Cells ¹

Øystein Fodstad; Inge Kjønniksen; Steinar Aamdal; Jahn M. Nesland; Michael R. Boyd; Alexander Pihl

Abstract

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Differentiation-induced ML-1 Cells as Targets for Transformation by a Chemical Carcinogen ¹

X-P. Guan; A. Bloch

Abstract

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Necrotizing Effect of Ethanedimethanesulfonate on Spontaneously Occurring Leydig Cell Tumors in Old F344 Rats

Sotokichi Morii; Yuji Naka; Toshihiko Inui; Hiroshi Shintani

Abstract

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Colorectal Cancer Risk, Chronic Illnesses, Operations, and Medications: Case Control Results from the Melbourne Colorectal Cancer Study ¹

Gabriel A. Kune; Susan Kune; Lyndsey F. Watson

Abstract

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Bladder Cancer in Relation to Cigarette Smoking ¹

Annamma Augustine; James R. Hebert; Geoffrey C. Kabat; Ernst L. Wynder

Abstract

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Laboratory Correlates of Adoptive Immunotherapy with Recombinant Interleukin-2 and Lymphokine-activated Killer Cells in Humans ¹

D. H. Boldt; B. J. Mills; B. T. Gemlo; H. Holden; J. Mier; E. Paietta; J. D. McMannis; L. V. Escobedo; I. Sniecinski; A. A. Rayner; M. J. Hawkins; M. B. Atkins; N. Ciobanu; T. M. Ellis

Abstract

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Immunospecific Saturable Clearance Mechanisms for Indium-111-labeled Anti-Melanoma Monoclonal Antibody 96.5 in Humans ¹

James L. Murray; Lamk M. Lamki; Linda J. Shanken; Mary E. Blake; Carl E. Plager; Robert S. Benjamin; Sally Schweighardt; Michael W. Unger; Michael G. Rosenblum

Abstract

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Acodazole Hydrochloride: Phase I Trial, Pharmacokinetics, and Evaluation of Cardiotoxicity in Dogs ¹

Richard Pazdur; Guy G. Chabot; Colin A. Campbell; Michael H. Lehmann; Robert A. Kloner; Laurence H. Baker

Abstract

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Activity of the Human Blood Group ABO, Se, H, Le, and X Gene-encoded Glycosyltransferases in Normal and Malignant Bladder Urothelium ¹

Torben F. Ørntoft; Hans Wolf; Winifred M. Watkins

Abstract

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Seventh Annual Sapporo Cancer Seminar: Primary and Secondary Prevention of Cancer ¹

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