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Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Articles

Tumor Heterogeneity

Gloria H. Heppner

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Antiproliferative Actions of Tamoxifen to Human Ovarian Carcinomas in Vitro¹

John S. Lazo; Peter E. Schwartz; Neil J. MacLusky; David C. Labaree; Amold J. Eisenfeld

Abstract

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Interaction among the Distinct Effects of Adenine and Guanine Depletion in Mouse Lymphoma Cells ¹

Binh Trong Nguyen; Yousry M. Sayed El; Wolfgang Sadée

Abstract

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Improved Therapeutic Index with High-Dose Methotrexate: Comparison of Thymidine-Purine Rescue with Citrovorum Factor Rescue in Mice ¹

Lawrence L. Samuels; James A. Straw

Abstract

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Effects of Chronic Ethanol Consumption on the Metabolism and Carcinogenicity of N′-Nitrosonornicotine in F344 Rats ¹

Andre Castonguay; Abraham Rivenson; Neil Trushin; Joel Reinhardt; Stella Spathopoulos; Carol J. Weiss; Betti Reiss; Stephen S. Hecht

Abstract

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Growth Rate of Control and β-Interferon-treated Human Fibroblast Populations over the Course of Their in Vitro Life Span ¹

Igor Tamm; Toyoko Kikuchi; Eugenia Wang; Lawrence M. Pfeffer

Abstract

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Correlation between Growth Inhibition and Presence of 5′-Methylthioadenosine in Cells Treated with Interferon ¹

Francesca de Ferra; Corrado Baglioni

Abstract

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Biological Activity and Receptor Binding of a Strongly Interacting Estrogen in Human Breast Cancer Cells ¹

Georg C. A. Reiner; Benita S. Katzenellenbogen; Rajeshwar D. Bindal; John A. Katzenellenbogen

Abstract

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Comparison of Drug Sensitivity among Tumor Cells within a Tumor, between Primary Tumor and Metastases, and between Different Metastases in the Human Tumor Colony-forming Assay ¹

Nobuhiko Tanigawa; Yoshifumi Mizuno; Takafumi Hashimura; Kazuo Honda; Kisaku Satomura; Yorinori Hikasa; Ohtsura Niwa; Tsutomu Sugahara; Osamu Yoshida; David H. Kem; Donald L. Morton

Abstract

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Cytokinetics of Macrophage-mediated Cytotoxicity ¹

S. J. Normann; J. Cornelius

Abstract

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Mutagenicity of the Enantiomers of the Diastereomeric Bay-Region Benzo(c)phenanthrene 3,4-Diol-1,2-epoxides in Bacterial and Mammalian Cells

Alexander W. Wood; Richard L. Chang; Wayne Levin; Dhiren R. Thakker; Haruhiko Yagi; Jane M. Sayer; Donald M. Jerina; Allan H. Conney

Abstract

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Role of the Cellular Oxidation-Reduction State in Methotrexate Binding to Dihydrofolate Reductase and Dissociation Induced by Reduced Folates ¹

Larry H. Matherly; Linda A. Anderson; I. David Goldman

Abstract

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Biotransformation of the Bladder Carcinogen N-[4-(5-Nitro-2-furyl)-2-thiazolyl]formamide in Mice ¹

Santhanam Swaminathan; George T. Bryan

Abstract

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Synergistic Antiproliferative Activity of Leukocyte Interferon in Combination with α-Difluoromethylornithine against Human Cells in Culture ¹

Michael G. Rosenblum; Jordan U. Gutterman

Abstract

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Enhancement of Thermal Response of Normal and Malignant Tissues by Corynebacterium parvum¹

M. Urano; T. Yamashita; H. D. Suit; L. E. Gerweck

Abstract

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New Storage Procedure for Human Tumor Biopsies prior to Estrogen Receptor Measurement ¹

Derek Crawford; Sheila Cowan; Salman Hyder; Marion McMenamin; David Smith; Robin Leake

Abstract

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Treatment of Human Glioma and Medulloblastoma Tumor Lines in Athymic Mice with Diaziquone and Diaziquone-based Drug Combinations

S. Clifford Schold, Jr.; Henry S. Friedman; Thorir D. Bjornsson; Darell D. Bigner

Abstract

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Interferon-induced Cell Cycle Changes in Human Hematopoietic Cell Lines and Fresh Leukemic Cells ¹

Göran Roos; Tomas Leanderson; Erik Lundgren

Abstract

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Activation of Tumor-cytostatic Macrophages with the Antitumor Agent 9,10-Anthracenedicarboxaldehyde Bis[(4,5-dihydro-1H-imidazole-2-yl)hydrazone] Dihydrochloride (Bisantrene)

Bosco Shang Wang; Araceli L. Lumanglas; Veronica M. Ruszala-Mallon; Frederick E. Durr

Abstract

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Fluorescence-activated Cell Sorting Analysis of the Induction and Expression of Acute Thermal Tolerance within the Cell Cycle ¹

Glenn C. Rice; Joe W. Gray; Phillip N. Dean; William C. Dewey

Abstract

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Positive Correlation between the Extent of Cell Proliferation and the Regulation of Base Excision Repair ¹

Thomas M. Vollberg; Kevin A. Lee; Michael A. Sirover

Abstract

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Protection by S-2-(3-Aminopropylamino)ethylphosphorothioic Acid against Radiation- and Cyclophosphamide-induced Attenuation in Antitumor Resistance ¹

Luka Milas; William H. McBride; Nancy Hunter; Hisao Ito

Abstract

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Origin of Increased Deoxycytidine Excretion into Urine of Rats Bearing Yoshida Ascites Sarcoma ¹

Mitsuhiro Shimizu; Shinji Fujimura

Abstract

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Antiproliferative Effect of Vitamin A on Xenotransplanted CaMa-15 Cells ¹

Neal T. Wetherall; William M. Mitchell; Susan A. Halter

Abstract

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Factors Affecting the Sensitivity of T-47D Human Breast Cancer Cells to Tamoxifen

Roger R. Reddel; Leigh C. Murphy; Robert L. Sutherland

Abstract

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Circulating Immune Complexes in Rats Bearing 6-Thioguanine-resistant Variants of the 13762 Mammary Adenocarcinoma ¹

Dave B. S. Hoon; Barry Ziola; Ian Ramshaw

Abstract

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Relation of Estrogen and Its Receptor to Rat Liver Growth and Regeneration ¹

Bernard Fisher; Nurten Gunduz; Elizabeth A. Saffer; Shu Zheng

Abstract

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In Vivo Effects of Indomethacin on the Growth of Murine Mammary Tumors ¹

Amy M. Fulton

Abstract

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Macromolecular and Cell Cycle Effects of Different Classes of Agents Inducing the Maturation of Human Myeloblastic Leukemia (ML-1) Cells ¹

Ruth W. Craig; Oskar S. Frankfurt; Hiroshi Sakagami; Ken Takeda; Alexander Bloch

Abstract

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Proliferation-linked Increase in Phosphoribosylformylglycinamidine Synthetase Activity (EC 6.3.5.3)¹

William L. Elliott; George Weber

Abstract

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Membrane Permeability as a Determinant of Dexamethasone Resistance in Murine Thymoma Cells ¹

Denise M. Johnson; Ronald F. Newby; Suzanne Bourgeois

Abstract

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Effects of X-Irradiation on Artificial Blood Vessel Wall Degradation by Invasive Tumor Cells ¹

Margaret A. Heisel; Walter E. Laug; Stephen M. Stowe; Peter A. Jones

Abstract

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Inhibited Growth of a Reticulum Cell Sarcoma (M5076) Induced in Vitro and in Vivo by Macrophage-activating Agents ¹

J. E. Talmadge; I. R. Hart

Abstract

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Temporal Dissociation in the Exposure Times Required for Maximal Induction of Cytotoxicity, Mutation, and Transformation by N-Methyl-N′-nitro-N-nitrosoguanidine in the BALB/3T3 CIA31-1-1 Cell Line

Margherita Bignami; Corrado Ficorella; Eugenia Dogliotti; Richard L. Norman; M. Edward Kaighn; Umberto Saffiotti

Abstract

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Stimulation of Rat Colonic Crypt Cell Proliferative Activity by Wheat Bran Consumption during the Stage of 1,2-Dimethylhydrazine Administration ¹

Lucien R. Jacobs

Abstract

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Treatment of Murine Testicular Leukemia ¹

W. Keith Hoots; J. Arly Nelson

Abstract

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Sensitivity of Human Cell Strains Having Different Abilities to Repair O⁶-Methylguanine in DNA to Inactivation by Alkylating Agents Including Chloroethylnitrosoureas

Dominic A. Scudiero; Sharon A. Meyer; Brian E. Clatterbuck; Michael R. Mattern; Chuck H. J. Ziolkowski; Rufus S. Day, III

Abstract

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Enzymic Capacities of Purine de Novo and Salvage Pathways for Nucleotide Synthesis in Normal and Neoplastic Tissues ¹

Yutaka Natsumeda; Noemi Prajda; John P. Donohue; John L. Glover; George Weber

Abstract

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Biotransformations of Daunorubicin Aglycones by Rat Liver Microsomes ¹

Herbert S. Schwartz; Brajeswar Paul

Abstract

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Effect of Nicotinamide Analogues on Recovery from DNA Damage in C3H 10T½ Cells ¹

Elaine L. Jacobson; Janice Yoder Smith; Mingkwan Mingmuang; René Meadows; James L. Sims; Myron K. Jacobson

Abstract

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Potentiation of Methotrexate Toxicity by Dipyridamole ¹

J. Arly Nelson; Stephanie Drake

Abstract

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Cellular Basis for Adriamycin-induced Augmentation of Cell-mediated Cytotoxicity in Culture ¹

M. Jane Ehrke; Kazuo Ryoyama; Stefan A. Cohen

Abstract

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Enhanced Lymphatic Delivery of Mitomycin C Conjugated with Dextran ¹

Yoshinobu Takakura; Satoshi Matsumoto; Mitsuru Hashida; Hitoshi Sezaki

Abstract

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Evidence for Cell Cycle Phase-specific Initiation of a Program of HL-60 Cell Myeloid Differentiation Mediated by Inducer Uptake ¹

Andrew Yen; Kevin L. Albright

Abstract

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Flow Cytometric Determination of Estrogen Receptors in Intact Cells ¹

Ronald W. Oxenhandler; Roy McCune; Alice Subtelney; Charles Truelove; Harry W. Tyrer

Abstract

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Identification of the Major Adducts Formed by Reaction of 5-Methylchrysene Anti-Dihydrodiol-Epoxides with DNA in Vitro¹

Assieh A. Melikian; Shantu Amin; Stephen S. Hecht; Dietrich Hoffmann; John Pataki; Ronald G. Harvey

Abstract

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Comparison of Growth of Human Bladder Cancer in Tissue Culture or as Xenografts with Clinical and Pathological Characteristics ¹

A. Kovnat; R. N. Buick; J. G. Connolly; M. A. Jewett; A. G. Keresteci; I. F. Tannock

Abstract

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Cytotoxic and Biochemical Effects of Thymidine and 3-Deazauridine on Human Tumor Cells ¹

Arnold Lockshin; John T. Mendoza; Beppino C. Giovanella; John S. Stehlin, Jr.

Abstract

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4-Aminoazobenzene and N,N-Dimethyl-4-aminoazobenzene as Equipotent Hepatic Carcinogens in Male C57BL/6 × C3H/He F₁ Mice and Characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the Major Persistent Hepatic DNA-bound Dye in These Mice ¹

K. Barry Delclos; W. Gary Tarpley; Elizabeth C. Miller; James A. Miller

Abstract

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Use of 5-Fluorodeoxycytidine and Tetrahydrouridine to Exploit High Levels of Deoxycytidylate Deaminase in Tumors to Achieve DNA- and Target-directed Therapies ¹

John A. Mekras; David A. Boothman; Liliana M. Perez; Sheldon Greer

Abstract

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Multiple Tumoricidal Effector Mechanisms Induced by Adriamycin ¹

Daniel Salazar; Stefan A. Cohen

Abstract

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Serum Pseudouridine as a Biochemical Marker in the Development of AKR Mouse Lymphoma ¹

Tommaso Russo; Alfredo Colonna; Francesco Salvatore; Filiberto Cimino; Sandra Bridges; Corrado Gurgo

Abstract

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Murine Strain Differences in Ovotoxicity following Intraovarian Injection with Benzo(a)pyrene, (+)-(7R,8S)-Oxide, (-)-(7R,8R)-Dihydrodiol, or (+)-(7R,8S)-Diol-(9S,10R)-epoxide-2

Ken Takizawa; Haruhiko Yagi; Donald M. Jerina; Donald R. Mattison

Abstract

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Identification of Melanoma-associated Antigens Using Fixed Tissue Screening of Antibodies ¹

Barbara Atkinson; Carolyn S. Emst; Barbara F. D. Ghrist; Meenhard Herlyn; Magdalena Blaszczyk; Alonzo H. Ross; Dorothee Herlyn; Zenon Steplewski; Hilary Koprowski

Abstract

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Response of Hepatocytes Transplanted into Syngeneic Hosts and Heterotransplanted into Athymic Nude Mice to Peroxisome Proliferators ¹

Janardan K. Reddy; Randy L. Jirtle; Thomas K. Watanabe; Neerad K. Reddy; George Michalopoulos; Saeed A. Qureshi

Abstract

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Differential Expression of Intermediate-Filament Proteins in Murine Sarcoma 180 Ascites or Solid Tumor

Annette Günther; Mitsuru Kinjo; Hermelita Winter; Jaroslav Sonka; Manfred Volm

Abstract

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Immunoradiometric and Immunohistochemical Demonstration of Neuron-specific Enolase in Experimental Rat Gliomas ¹

Stanley A. Vinores; Paul J. Marangos; Jose M. Bonnin; Lucien J. Rubinstein

Abstract

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Characteristics of a New Human Neuroblastoma Cell Line Which Differentiates in Response to Cyclic Adenosine 3′:5′-Monophosphate ¹

H. Thomas Rupniak; Glen Rein; John F. Powell; Tim A. Ryder; Susan Carson; Susan Povey; Bridget T. Hill

Abstract

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Transplantability of Naturally Occurring Benign and Malignant Neoplasms and Age-associated Nonneoplastic Lesions of the Aging F344 Rat as Biological Evidence for the Histological Diagnosis of Neoplasms ¹

Jerrold M. Ward; Peter H. Lynch

Abstract

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Differentiation Properties of Avian Tumor Cell Lines: Analysis Using Chicken Fetal Antigen and Other Markers ¹

Kathryn A. Trembicki; Muquarrab A. Qureshi; Rodney R. Dietert

Abstract

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Increase in Type I Cyclic Adenosine 3′:5′-Monophosphate-dependent Protein Kinase Activity and Specific Accumulation of Type I Regulatory Subunits in Adenovirus Type 12-transformed Cells ¹

Nada Ledinko; I-JA David Chan

Abstract

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A Method for Dissociation of Viable Human Breast Cancer Cells That Produces Flow Cytometric Kinetic Information Similar to That Obtained by Thymidine Labeling ¹

Robert W. McDivitt; Kenneth R. Stone; John S. Meyer

Abstract

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Alteration in the Distribution of the Epidermal Protein Filaggrin during Two-Stage Chemical Carcinogenesis in the SENCAR Mouse Skin ¹

M. D. Mamrack; A. J. P. Klein-Szanto; J. J. Reiners, Jr.; T. J. Slaga

Abstract

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Cytotoxic and Cytodifferentiative Components of 6-Thioguanine Resistance in HL-60 Cells Containing Acquired Double Minute Chromosomes

Robert E. Gallagher; Anna C. Ferrari; Alan W. Zulich; Ray-Whay Chiu Yen; Joseph R. Testa

Abstract

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Evidence for a Direct Growth-stimulating Effect of Estradiol on Human MCF-7 Cells in Vivo¹

Robert A. Huseby; Terry M. Maloney; Charles M. McGrath

Abstract

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A Four-Day Subrenal Capsule Assay for Testing the Effectiveness of Anticancer Drugs against Human Tumors ¹

Francis A. Levi; Jean Pierre Blum; Guy Lemaigre; Charlotte Bourut; Alain Reinberg; Georges Mathé

Abstract

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Cholesterol-induced Growth Stimulation, Cell Aggregation, and Membrane Properties of Ascites Tumor Cells in Culture ¹

E. W. Haeffner; C. J. K. Hoffmann; M. Stoehr; H. Scherf

Abstract

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Analysis of Methylglyoxal Bis(guanylhydrazone)-induced Alterations of Hamster Tumor Mitochondria by Correlated Studies of Selective Rhodamine Binding, Ultrastructural Damage, DNA Replication, and Reversibility ¹

Margit M. K. Nass

Abstract

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Functional Changes in the Regulatory Subunit of the Type II Cyclic Adenosine 3′:5′-Monophosphate-dependent Protein Kinase Isozyme during Normal and Neoplastic Lung Development ¹

Martin S. Butley; David G. Beer; Alvin M. Malkinson

Abstract

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Changes in Molecular Forms of Rat Hepatic Glutathione S-Transferase during Chemical Hepatocarcinogenesis ¹

Akio Kitahara; Kimihiko Satoh; Koya Nishimura; Takashi Ishikawa; Kazuo Ruike; Kiyomi Sato; Hiroyuki Tsuda; Nobuyuki Ito

Abstract

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A Monoclonal Antibody to a Human Breast Tumor Protein Released in Response to Estrogen ¹

Alan C. Brabon; Jeffrey F. Williams; Robert D. Cardiff

Abstract

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A Morphometric Study of Dedifferentiated and Involutional Dark Keratinocytes in 12-O-Tetradecanoylphorbol-13-acetate-treated Mouse Epidermis ¹

M. Chiba; T. J. Slaga; A. J. P. Klein-Szanto

Abstract

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Abnormal Profile of Serum Proteinase Inhibitors in Cancer Patients ¹

Rajender K. Chawla; Douglas J. Rausch; Frederick W. Miller; W. Ralph Vogler; David H. Lawson

Abstract

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Monoclonal Antibody MCS-2 as the Marker of Phorbol Diester-induced Myeloid Differentiation in Acute Undifferentiated Leukemia ¹

Sheryl L. Gregg; Kazimiera J. Gajl-Peczalska; Tucker W. LeBien; Clara D. Bloomfield; Richard Brunning; Kimitaka Sagawa

Abstract

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Correspondence re: M. I. Bemhard, K. M. Hwang, K. A. Foon, A. M. Keenan, R. M. Kessler, J. M. Frincke, D. J. Tallam, M. G. Hanna, Jr., L. Peters, and R. K. Oldham. Localization of ¹¹¹In- and ¹²⁵I-labeled Monoclonal Antibody in Guinea Pigs Bearing Line 10 Hepatocarcinoma Tumors. Cancer Res., 43: 4429–4433, 1983–Reply

Michael Bernhard; Robert K. Oldham; Kenneth A. Foon; Andrew Keenan

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Correspondence re: M. I. Bemhard, K. M. Hwang, K. A. Foon, A. M. Keenan, R. M. Kessler, J. M. Frincke, D. J. Tallam, M. G. Hanna, Jr., L. Peters, and R. K. Oldham. Localization of ¹¹¹In- and ¹²⁵I-labeled Monoclonal Antibody in Guinea Pigs Bearing Line 10 Hepatocarcinoma Tumors. Cancer Res., 43: 4429–4433, 1983: The Importance of Traditional Methods of Measuring Tracer Biodistributions

Lawrence E. Williams

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Use of Two Sequential Applications of Initiators in the Production of Hepatomas in the Rat: An Examination of the Solt-Farber Protocol

Van Rensselaer Potter

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Henry S. Kaplan 1918–1984

Saul A. Rosenberg

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Leonell C. Strong 1894–1982

Michael B. Shimkin

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