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Targeting the Tumor Microenvironment

Cancer therapy has evolved beyond solely targeting cancer cells and now considers the tumor microenvironment (TME) as well. The cellular and acellular components that comprise the TME can have a substantial impact on tumor progression and response to therapy. This collection features a sampling of recent studies published in Cancer Research that provide new insights into how the TME can impact therapeutic resistance, as well as strategies to reprogram the TME to combat cancer.

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Makoto Matsushita; Kazutoshi Fujita; Takuji Hayashi; Hisako Kayama; Daisuke Motooka; Hiroaki Hase; Kentaro Jingushi; Gaku Yamamichi; Satoru Yumiba; Eisuke Tomiyama; Yoko Koh; Yujiro Hayashi; Kosuke Nakano; Cong Wang; Yu Ishizuya; Taigo Kato; Koji Hatano; Atsunari Kawashima; Takeshi Ujike; Motohide Uemura; Ryoichi Imamura; Maria D.C. Rodriguez Pena; Jennifer B. Gordetsky; George J. Netto; Kazutake Tsujikawa; Shota Nakamura; Kiyoshi Takeda; Norio Nonomura
George Sharbeen; Joshua A. McCarroll; Anouschka Akerman; Chantal Kopecky; Janet Youkhana; John Kokkinos; Jeff Holst; Cyrille Boyer; Mert Erkan; David Goldstein; Paul Timpson; Thomas R. Cox; Brooke A. Pereira; Jessica L. Chitty; Sigrid K. Fey; Arafath K. Najumudeen; Andrew D. Campbell; Owen J. Sansom; Rosa Mistica C. Ignacio; Stephanie Naim; Jie Liu; Nelson Russia; Julia Lee; Angela Chou; Amber Johns; Anthony J. Gill; Estrella Gonzales-Aloy; Val Gebski; Yi Fang Guan; Marina Pajic; Nigel Turner; Minoti V. Apte; Thomas P. Davis; Jennifer P. Morton; Koroush S. Haghighi; Jorjina Kasparian; Benjamin J. McLean; Yordanos F. Setargew; Phoebe A. Phillips
Pierre-Benoit Ancey; Caroline Contat; Gael Boivin; Silvia Sabatino; Justine Pascual; Nadine Zangger; Jean Yannis Perentes; Solange Peters; E. Dale Abel; David G. Kirsch; Jeffrey C. Rathmell; Marie-Catherine Vozenin; Etienne Meylan
Nicholas R. Anderson; Nicholas G. Minutolo; Saar Gill; Michael Klichinsky
Eugen Dhimolea; Ricardo de Matos Simoes; Dhvanir Kansara; Xiang Weng; Shruti Sharma; Pallavi Awate; Zhiyi Liu; Dong Gao; Nicholas Mitsiades; Joseph H. Schwab; Yu Chen; Rinath Jeselsohn; Aedín C. Culhane; Myles Brown; Irene Georgakoudi; Constantine S. Mitsiades
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