Summary
The synthesis of 0.01 millimole of diphenyl p-iodophenyl tetrazolium chloride from radioactive iodine (I131) is described. Following the intravenous injection of the radioactive tetrazolium salt into normal and tumor-bearing mice, radioactivity disappeared rapidly from the circulating blood, and appeared in greatest amount in kidney, liver, and lung. Sarcoma 37 contained less radioactivity than most other tissues.
*
This investigation was aided by a research grant from the National Cancer Institute, National Institutes of Health, U.S. Public Health Service.
†
Acknowledgment is due Mr. Myron Milden for technical assistance.
This content is only available via PDF.
©1949 American Association for Cancer Research.
1949
Cancer Research, Inc.