Background: Late-stage breast cancer rates in the Pacific where mammography services are limited are exceedingly high. Therefore, alternative accessible breast cancer screening technologies such as portable ultrasound is needed. However, little is known about the performance of portable ultrasound when compared to clinical ultrasound for use in breast cancer screening. By utilizing 3D printing technology, it is possible to design breast phantom inserts to replicate various types of lesions. In this study, we utilized 3D printed breast phantom inserts to compare portable and clinical ultrasound lesion detection performance. Methods: Four different breast inserts were designed using FreeCAD (version 0.19) to replicate different lesion detection properties. The first insert compares lesion shape, the second insert investigates depth and size, the third insert looks at fiber diameter, and the fourth insert looks at clusters. The four inserts were printed using a photopolymer resign (Formlabs Inc Rigid resign, Somerville, MA, USA) and then placed in a gelatin-based breast phantom designed for ultrasound use. Using the portable ultrasound (GE Vscan Extend) and clinical ultrasound (Philips EPIQ 5G), various images were captured of identical angle and orientation for both devices. The number of lesions visualized were counted and presented as a percentage of lesions detected. Results: The portable ultrasound had a 100% lesion detection rate for breast insert 1, 90.3% for breast insert 2, 70% for breast insert 3 and 55.8% for breast insert 4. Clinical ultrasound had 100% lesion detection rate for breast insert 1, 93.1% for breast insert 2, 76.6% for breast insert 3, and 99% for breast insert 4. Conclusion: Portable ultrasound shows comparable lesion detection capabilities to clinical ultrasound in 3 of the 4 breast phantom insert tests. Portable ultrasound may have potential as a capable accessible breast cancer screening device in areas without mammography.

Citation Format: Dustin Valdez, Jami Fukui, Thomas Wolfgruber, Lambert Leong, Gertraud Maskarinec, John Shepherd. Comparing portable and clinical ultrasound systems using 3D printed breast phantom inserts [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P3-01-13.