Retraction: Gemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF

This article (1) has been retracted at the request of the editors. Following an institutional review by Wayne State University (Detroit, MI), the primary affiliation for several of the authors, it was determined that the article (1) included multiple instances of data falsification and/or fabrication including data reuse, cutting/pasting, relabeling, inappropriate covering or removal of dots and smudges, overlaying/masking, and data composition. Specifically, the review found multiple instances of inappropriate image manipulation of the PTEN, pAkt, and tropomyosin Western blot bands from the MIAPaCa-E experiments and the PTEN and tropomyosin bands from the MIAPaCa-M experiments in Fig. 3A, and a fabricated composite Western blot of pAKT and PTEN (Fig. 3C) and PTEN (Fig. 3D) constructed from bands taken from multiple sources. As a result of these findings, the institution recommended retraction and, upon internal review, the editors agree with this recommendation.

A copy of this Retraction Notice was sent to the last known email addresses for five of the nine authors. One author (P.A. Philip) agreed to the retraction; four authors (A. Ahmad, S. Banerjee, Z. Wang, and F.H. Sarkar) did not respond; the four remaining authors (S. Ali, S. Padhye, K. Dominiak, and J.M. Schaffert) could not be located.