In this article (Cancer Res 2013;73:7111–21), which was published in the December 1, 2013, issue of Cancer Research (1), an article (ref. 27, Cao and colleagues, J Biol Chem 2010;285:31840–8) was cited incorrectly, and the correct citation (Glinka and colleagues, Carcinogenesis 2011;32:613–21) was not included.
The citation of ref. 27 on page 7,115 should read as follows:
In hepatic stellate cells, NRP1 knockdown was shown to shift SMAD phosphorylation from SMAD2/3 to SMAD1/5 (27). However, we have shown that in multiple experiments under a variety of conditions, NRP2 knockdown had no effect on SMAD2/3 or SMAD1/5 phosphorylation in these lung cancer cells.
The citation of ref. 27 on page 7,118 should read as follows:
In hepatic stellate cells exposed to TGF-β1, NRP1 knockdown was shown to reduce SMAD2/3 and increase SMAD1/5 phosphorylation (27). In addition, NRP1 has been shown to activate SMAD2/3 in breast cancer cells, whereas Nrp2 could “activate LAP–TGFβ1 (data not shown)” (61). These authors indicated that “Nrp1 and Nrp2 might be largely interchangeable in their interactions with TGFβ components.” However, we found that in lung cancer cells, NRP2 knockdown had no effect on SMAD signaling. Thus, the two NRPs are not equivalent in this context.
The new ref. 61 is as follows:
61. Glinka Y, Stoilova S, Mohammed N, Prud'homme GJ. Neuropilin-1 exerts coreceptor function for TGF-β-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-β. Carcinogenesis 2011;32:613–21.
The authors regret this error.
