In the article on autoantibodies in breast cancer in the August 1, 2004 issue of Cancer Research (1), in , the entry for UP 859 was incorrect. The corrected table appears below with the correct entry corresponding to elongation factor-2 in bold.

Table 6.

Possible diagnostic markers for DCISa of the breast

cDNA identity*GenBank accnbpDCISIDCP
Annexin XI-A (CB331917) NP_001148 205–418 <0.0001 
NIFK (CB331935)34 AAH12457 667–898 <0.0001 
KIAA1671 (CB331932)32 BAB33341 447–800 <0.0001 
UP96 (CF751987) nsh  0.0010 
UP104 (CF751988–9)§ nsh  0.0045 
Ribosomal protein S6 (CB331938)29 AB062123 416–653 0.0107 
Cyclin K (CB331940)33 AF542236 32652–32475 0.0118 
UP94 (CF751987) nsh  0.0118 
UP107 (CK235960) nsh  0.0118 
Grb2-AP2 (CB331927)39,40a NP_036428 1506–1599 0.0250 
Elongation factor-2 (CB331921) P09445 2495–2580 2 0 0.0250 
UP455 (CF751964) nsh  22 0.0371 
cDNA identity*GenBank accnbpDCISIDCP
Annexin XI-A (CB331917) NP_001148 205–418 <0.0001 
NIFK (CB331935)34 AAH12457 667–898 <0.0001 
KIAA1671 (CB331932)32 BAB33341 447–800 <0.0001 
UP96 (CF751987) nsh  0.0010 
UP104 (CF751988–9)§ nsh  0.0045 
Ribosomal protein S6 (CB331938)29 AB062123 416–653 0.0107 
Cyclin K (CB331940)33 AF542236 32652–32475 0.0118 
UP94 (CF751987) nsh  0.0118 
UP107 (CK235960) nsh  0.0118 
Grb2-AP2 (CB331927)39,40a NP_036428 1506–1599 0.0250 
Elongation factor-2 (CB331921) P09445 2495–2580 2 0 0.0250 
UP455 (CF751964) nsh  22 0.0371 

NOTE: aDCIS, ductal carcinoma in situ; Grb2-AP2, Grb2-associated protein 2; IDC, invasive ductal carcinoma; nsh, no significant homology; UP, unknown protein. The total number of subjects with DCIS is 15 and that with IDC of the breast is 75. The P value was determined by χ-square with Yates correction for small values and ns is a P > 0.05. Autoantigens are listed in order of decreasing significance.

*

The GenBank expressed sequence tag accession numbers assigned to the identified partial sequences are included in parentheses in the cDNA identity column.

Accession numbers listed under GenBank accn indicate the identity of the known protein identical to the phage cloned.

bp is the partial base pair sequence of known proteins identified from the cloning.

§

Denotes that PCR and sequence analysis revealed more than one product, each with a different sequence.

Denotes association of reactivity with more than one phage, annexin XI-A (17), ribosomal protein S6 (2), Grb2-associated protein 2 (2), each of which has the number of positive breast cancer sera, non-cancer sera, and P values expressed for the group of identical phages as a combined unit.

1
Fernández-Madrid F, Tang N, Alansari H, Granda JL, Tait L, Amirikia KC, Moroianu M, Wang X, Karvonen RL. Autoantibodies to annexin XI-A and other autoantigens in the diagnosis of breast cancer.
Cancer Res
2004
;
64
:
5089
–96.