In the article on autoantibodies in breast cancer in the August 1, 2004 issue of Cancer Research (1), in , the entry for UP 859 was incorrect. The corrected table appears below with the correct entry corresponding to elongation factor-2 in bold.
Possible diagnostic markers for DCISa of the breast
cDNA identity* . | GenBank accn† . | bp‡ . | DCIS . | IDC . | P . |
---|---|---|---|---|---|
Annexin XI-A (CB331917)† | NP_001148 | 205–418 | 9 | 8 | <0.0001 |
NIFK (CB331935)34 | AAH12457 | 667–898 | 5 | 0 | <0.0001 |
KIAA1671 (CB331932)32 | BAB33341 | 447–800 | 5 | 1 | <0.0001 |
UP96 (CF751987) | nsh | 4 | 1 | 0.0010 | |
UP104 (CF751988–9)§ | nsh | 4 | 2 | 0.0045 | |
Ribosomal protein S6 (CB331938)29∥ | AB062123 | 416–653 | 5 | 5 | 0.0107 |
Cyclin K (CB331940)33 | AF542236 | 32652–32475 | 3 | 1 | 0.0118 |
UP94 (CF751987) | nsh | 3 | 1 | 0.0118 | |
UP107 (CK235960) | nsh | 3 | 1 | 0.0118 | |
Grb2-AP2 (CB331927)39,40a | NP_036428 | 1506–1599 | 2 | 0 | 0.0250 |
Elongation factor-2 (CB331921) | P09445 | 2495–2580 | 2 | 0 | 0.0250 |
UP455 (CF751964) | nsh | 0 | 22 | 0.0371 |
cDNA identity* . | GenBank accn† . | bp‡ . | DCIS . | IDC . | P . |
---|---|---|---|---|---|
Annexin XI-A (CB331917)† | NP_001148 | 205–418 | 9 | 8 | <0.0001 |
NIFK (CB331935)34 | AAH12457 | 667–898 | 5 | 0 | <0.0001 |
KIAA1671 (CB331932)32 | BAB33341 | 447–800 | 5 | 1 | <0.0001 |
UP96 (CF751987) | nsh | 4 | 1 | 0.0010 | |
UP104 (CF751988–9)§ | nsh | 4 | 2 | 0.0045 | |
Ribosomal protein S6 (CB331938)29∥ | AB062123 | 416–653 | 5 | 5 | 0.0107 |
Cyclin K (CB331940)33 | AF542236 | 32652–32475 | 3 | 1 | 0.0118 |
UP94 (CF751987) | nsh | 3 | 1 | 0.0118 | |
UP107 (CK235960) | nsh | 3 | 1 | 0.0118 | |
Grb2-AP2 (CB331927)39,40a | NP_036428 | 1506–1599 | 2 | 0 | 0.0250 |
Elongation factor-2 (CB331921) | P09445 | 2495–2580 | 2 | 0 | 0.0250 |
UP455 (CF751964) | nsh | 0 | 22 | 0.0371 |
NOTE: aDCIS, ductal carcinoma in situ; Grb2-AP2, Grb2-associated protein 2; IDC, invasive ductal carcinoma; nsh, no significant homology; UP, unknown protein. The total number of subjects with DCIS is 15 and that with IDC of the breast is 75. The P value was determined by χ-square with Yates correction for small values and ns is a P > 0.05. Autoantigens are listed in order of decreasing significance.
The GenBank expressed sequence tag accession numbers assigned to the identified partial sequences are included in parentheses in the cDNA identity column.
Accession numbers listed under GenBank accn indicate the identity of the known protein identical to the phage cloned.
bp is the partial base pair sequence of known proteins identified from the cloning.
Denotes that PCR and sequence analysis revealed more than one product, each with a different sequence.
Denotes association of reactivity with more than one phage, annexin XI-A (17), ribosomal protein S6 (2), Grb2-associated protein 2 (2), each of which has the number of positive breast cancer sera, non-cancer sera, and P values expressed for the group of identical phages as a combined unit.