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The symposium was sponsored by The University of Texas M. D. Anderson Cancer Center and was held at the Del Lago Resort and Conference Center located outside of Houston, Texas, on November 6–10, 1992. Members of the organizing committee were Jaffer A. Ajani, V. Bruce Grossie, Jr., Robert C. Hickey, Anthony J. Mastromarino, and David M. Ota (all from M. D. Anderson Cancer Center); Mari K. Haddox (The University of Texas Health Science Center, Houston, TX); Gordon D. Luk (The University of Texas Southwestern Medical Center, Dallas, TX); and Courtney M. Townsend, Jr. (The University of Texas Medical Branch, Galveston, TX). Members of the international scientific advisory committee were W. Ki Hong and Victor A. Levin (M. D. Anderson Cancer Center); Uriel Bachrach (Hebrew University-Hadassah Medical School, Jerusalem, Israel); Seymour S. Cohen (Marine Biological Laboratory, Woods Hole, MA); Eugene W. Gerner (University of Arizona Health Science Center, Tucson, AZ); Olle Heby (University of Umeä, Umeä, Sweden); Juhani Jänne (University of Kuopio, Kuopio, Finland); Laurence J. Marton (University of Wisconsin Medical School, Madison, WI); David R. Morris (University of Washington, Seattle, WA); Nakaaki Ohsawa (Osaka Medical College, Osaka, Japan); Anthony E. Pegg (Pennsylvania State University College of Medicine, Hershey, PA); Carl W. Porter (Roswell Park Cancer Institute, Buffalo, NY); and Prasad S. Sunkara (Marion Merrell Dow Research Institute, Cincinnati, OH). The symposium was supported by the following: Abbott Laboratories; American Cancer Society, Texas Division, Inc.; Bristol-Myers Oncology Division; Chugai Pharm U.S.A., Inc.; Ciba-Geigy Limited; Daiichi Pharmaceutical Corp.; H. W. Davidson; The Max and Victoria Dreyfus Foundation, Inc.; Paul and Mary Haas Foundation; Philip S. Harper Foundation; Hobby Foundation; International Polyamine Research Fund; Robert E. and Evelyn McKee Foundation; Ryoji Odaka; The Alice Kleberg Reynolds Meyer Foundation; National Cancer Institute; The Ross Foundation; Shimadzu Scientific Instruments, Inc.; Margaret Dorrance Strawbridge Foundation of Pennsylvania 1, Inc.; Merck and Co., Inc., Human Health Division; Suntory Limited, Pharmaceutical Division; Toyobo America, Inc.; The Upjohn Co.; The Vaughn Foundation; Yamanouchi U. K. Ltd.

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