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Presented at the Symposium, “Discoveries and Opportunities in Cancer Research: A Celebration of the 50th Anniversary of the Journal Cancer Research,” May 15, 1991, during the 82nd Annual Meeting of the American Association for Cancer Research, Houston, TX.

Research cited in this paper that was conducted in the author's laboratory was supported by National Cancer Institute Grants CA01111 and 02656, ACS Grant SIG-13A, The Markey Charitable Trust, the Yakult-Honsha Company, and the National Foundation for Cancer Research.

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