The occurrence of shared nonviral tumor-associated antigens among 18 immunogenic C3H/He mammary carcinomas was investigated in vivo. By cross-immunization and s.c. challenge between pairs of tumors in 37 different combinations, six of the tumors were found to cross-immunize with one to three other tumors. A minimum of three different antigenic specificities were found to be shared among cross-reacting tumors.

1

Supported by USPHS grant CA 29660 (formerly CA 15960) from the National Cancer Institute. The work was started at the Pondville Hospital, Walpole, MA, and completed at Roswell Park Memorial Institute, Buffalo, NY.

This content is only available via PDF.
©1984 American Association for Cancer Research.
1984
Cancer Research, Inc.