Abstract
The human pancreatic cancer cell line COLO 357 has been xenografted s.c. in athymic Swiss mice. The xenografts grew well to form typical adenosquamous carcinomas. The cells were placed in a perfused artificial capillary system where they formed a solid tumor mass which survived for 7 weeks. In this system, the cells consumed glucose and released enzymes and carcinoembryonic antigen into the extracapillary space.
1
Supported by Grant CA 24485, from the National Pancreatic Cancer Project; Grants CA 30035, CA 13943, CA 20892, and CA 15018 from the National Cancer Institute, United States Department of Health and Human Services; and by a grant from the Veterans Administration.
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©1983 American Association for Cancer Research.
1983
Cancer Research, Inc.