The HL-A antigenic profiles of cells derived from four thymomas, one thymic seminoma, and one normal and four hyperplastic thymuses were qualitatively identical to those of the peripheral lymphocytes of the same patients. Quantitatively, the thymic tissue appeared to contain somewhat less HL-A antigenic reactivity than did peripheral lymphocytes. Sera of 26 patients with myasthenia gravis failed to show cytotoxic reaction with thymic cells.

1

Supported by USPHS Grant AI-10088 and by grants from the Blood Bank of San Bernardino-Riverside Counties and the California Chapter of the Myasthenia Gravis Foundation.

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©1974 American Association for Cancer Research.
1974
Cancer Research, Inc.