Treatment of Chinese hamster embryo cells with 4-nitroquinoline 1-oxide prior to infection with SV40 increases the frequency of cell transformation, the level of nuclear penetration of SV40, and the amount of SV40 DNA integrated into cell DNA.

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Supported in part by American Cancer Society Grants VC-73 and PRP-45 and by USPHS Research Grants CA-10815 and CA-08936 from the National Cancer Institute.

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©1974 American Association for Cancer Research.
1974
Cancer Research, Inc.