The data from this preliminary experiment make it appear that continuous administration of progesterone protects animals from the synergism between estrogen and radiation. However, it also appears that the progesterone has by itself a protective effect against the individual carcinogenic agents since fewer tumors occurred on the opposite side as well as on the radiated side. In this preliminary experiment none of the animals that bore just progesterone pellets and were radiated developed mammary carcinomata.

1

This study was supported by Grant 103-70 from the Cancer Association of Greater New Orleans.

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©1973 American Association for Cancer Research.
1973
Cancer Research, Inc.