Data are reported on 1422 plant extracts which were tested in the primary screens of the Cancer Chemotherapy National Service Center. Almost all the materials were tested in Sarcoma 180, Adenocarcinoma 755, Leukemia 1210, and KB cells in culture; some tests were also carried out in Dunning leukemia ascites, Lewis lung carcinoma, Walker 256 (intramuscular), Human sarcoma HSl, Friend virus leukemia, P-1798 lymphosarcoma and Melanotic melanoma. Data are reported only on materials which have not demonstrated sufficient activity in these systems to warrant further investigation. The number of test systems in the screening program has recently been reduced; the reasons for the reduction are discussed.

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