The s.c. injection of talc, MgSiO3, into mice results in a decrease of hepatic catalase activity. A transient, but marked rise in catalase activity was observed on the 4th day following tale injection. This rise in activity was manifest primarily in the mitochondrial fraction. A concomitant increased incorporation of radioactive leucine occurred in the microsomal fraction. The relationship between the increased catalase activity and increased incorporation of leucine is discussed with respect to enzyme biosynthesis.

1

Supported in part by a grant (CA 03152-8) from the National Cancer Institute, USPHS, and by the American Cancer Society (Illinois Division).

This content is only available via PDF.
©1966 American Association for Cancer Research.
1966
Cancer Research, Inc.