A new, transplantable tumor of the Syrian golden hamster has been described. This tumor, a leiomyosarcoma, arose in a male hamster which had been previously implanted subcutaneously with a cholesterol pellet. It grows progressively in 100 per cent of the hosts following subcutaneous implantation. Metastases have been observed in several organs.

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This investigation was supported in part by an institutional grant of the American Cancer Society and by a grant from the National Cancer Institute, National Institutes of Health, United States Public Health Service, and the Mass. Division of the American Cancer Society.

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