1. A 32 per cent incidence of tumors was induced in rats by the subcutaneous imbedding of silver foil. Sarcomas were induced in lower incidence by vitallium, tantalum, and stainless steel foils.

  2. The tumors produced were fibrosarcomas, with one osteogenic sarcoma.

  3. Tin foil did not cause any tumor induction.

  4. Possible mechanisms are tentatively discussed.

*

This investigation was supported by a research grant, No. C-1620 (C 2-3-4) from the National Cancer Institute, National Institutes of Health, United States Public Health Service.

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©1956 American Association for Cancer Research.
1956
Cancer Research, Inc.