Summary
The interaction of isomers of aminofluorene and aminofluorenone with montmorillonite was studied. Most of the fluorene derivatives having an amino group in the 2-position produced a color change. Evidence is presented showing that the color reaction involves tautomerism forming an activated dipole. It is postulated that the activated tautomers are carcinogenic. The nitrogen in an aminofluorene is considered to be the most active site in the molecule capable of interacting with a protein.
This content is only available via PDF.
©1956 American Association for Cancer Research.
1956
Cancer Research, Inc.