1. Transplantation of 33 human tumors into the cheek pouch of cortisone-treated hamsters has resulted in the ‘survival” of 70 per cent of the tumors for periods exceeding 12 days.

  2. One epidermoid carcinoma, now called “Deac-1,” holds promise of being permanently transplantable. It has now been carried through sixteen generations of hamsters in a 9-month period.

  3. Factors concerned in the eventual transplantation of other human neoplasms are briefly discussed, and possibilities for immediate clinical application of experimental data are suggested.

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This work was supported by funds from the American Cancer Society and United States Atomic Energy Commission Contract AT(30-1)-901 with the New England Deaconess Hospital.

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