The site of production of the lactic dehydrogenase (LDH) that appears in the plasma of leukemic mice has been studied by technics employing various analogs of nicotinamide adenine dinucleotide. The LDH of several normal organs was characterized and shown to differ from the enzyme which appears in the leukemic plasma. The most likely source of the enzyme, based on these studies, is the tumor cell itself.

This content is only available via PDF.