Marked augmentation of radiotherapeutic “cure” rates upon mammary adenocarcinoma 755 was obtained by combined treatment with two chemical agents (6-aminonicotinamide + 6-mercaptopurine) and x-ray.

The data recommend similar methodology—radiotherapy + adjuvant chemotherapy—for clinical evaluation of these two agents upon solid tumors.

*

This work was supported in part by grant CY-2446 (C2) from the National Institutes of Health, Public Health Service.

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©1958 American Association for Cancer Research.
1958
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