*

Most of this material was presented at the 49th Annual Meeting of the American Association for Cancer Research in Philadelphia, April 11, 1958, as part of a Symposium on “Recent Contributions of Tissue Culture to Cancer Research.”. The experimental work of the author and his associates mentioned in this paper has been supported by U.S. Public Health Service Research Grants C-1894 and C-2332 and by the Charles Ulrick and Josephine Bay Gift for Research in Brain Tumor Chemotherapy.

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