Twenty-two male Wistar albino rats, inoculated subcutaneously with methylcholanthrene, and fourteen females of the same strain, with spontaneous mammary tumors, were sacrificed at various stages of tumor size (0–171 gm.). The growths were encapsulated, and no metastases were seen. Body weight and tumor weight, wet and dry weight of the liver, and nitrogen content of the dry liver were determined. From these data the nitrogen of the liver, relative to body weight without according to the weight of the carcass plus the weight of the tumor, the relative nitrogen content of the liver was the same as in normal rats.

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