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Journal Articles

Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non–Small Cell Lung Carcinogenesis

Tianshun Zhang, Ruihua Bai, Qiushi Wang, Keke Wang, Xiang Li, Kangdong Liu, Joohyun Ryu, Ting Wang, Xiaoyu Chang, Weiya Ma, Ann M. Bode, Qingxin Xia, Yongping Song, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2019) 12 (12): 837–848.
https://doi.org/10.1158/1940-6207.CAPR-19-0211
Published: 03 December 2019
View article titled, Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non–Small Cell Lung Carcinogenesis
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Includes: Supplementary data
Journal Articles

Scutellarin Suppresses Patient-Derived Xenograft Tumor Growth by Directly Targeting AKT in Esophageal Squamous Cell Carcinoma

Feifei Liu, Xueyin Zu, Xiaomeng Xie, Yuanyuan Zhang, Kangdong Liu, Hanyong Chen, Ting Wang, Ann M. Bode, Zigang Dong, Dong Joon Kim
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2019) 12 (12): 849–860.
https://doi.org/10.1158/1940-6207.CAPR-19-0244
Published: 03 December 2019
View article titled, Scutellarin Suppresses Patient-Derived Xenograft Tumor Growth by Directly Targeting AKT in Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

The Ashitaba (Angelica keiskei) Chalcones 4-hydroxyderricin and Xanthoangelol Suppress Melanomagenesis By Targeting BRAF and PI3K

Tianshun Zhang, Qiushi Wang, Mangaladoss Fredimoses, Ge Gao, Keke Wang, Hanyong Chen, Ting Wang, Naomi Oi, Tatyana A. Zykova, Kanamata Reddy, Ke Yao, Weiya Ma, Xiaoyu Chang, Mee-Hyun Lee, Moeez Ghani Rathore, Ann M. Bode, Hitoshi Ashida, Scott M. Lippman, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2018) 11 (10): 607–620.
https://doi.org/10.1158/1940-6207.CAPR-18-0092
Published: 02 October 2018
View article titled, The Ashitaba (<em>Angelica keiskei</em>) Chalcones 4-hydroxyderricin and Xanthoangelol Suppress Melanomagenesis By Targeting BRAF and PI3K
Open the PDF for The Ashitaba (<em>Angelica keiskei</em>) Chalcones 4-hydroxyderricin and Xanthoangelol Suppress Melanomagenesis By Targeting BRAF and PI3K in another window
Includes: Supplementary data
Journal Articles

Pharmacological TLR4 Antagonism Using Topical Resatorvid Blocks Solar UV-Induced Skin Tumorigenesis in SKH-1 Mice

Karen Blohm-Mangone, Nichole B. Burkett, Shekha Tahsin, Paul B. Myrdal, Alhassan Aodah, Brenda Ho, Jaroslav Janda, Michelle McComas, Kathylynn Saboda, Denise J. Roe, Zigang Dong, Ann M. Bode, Emanuel F. Petricoin, III, Valerie S. Calvert, Clara Curiel-Lewandrowski, David S. Alberts, Georg T. Wondrak, Sally E. Dickinson
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2018) 11 (5): 265–278.
https://doi.org/10.1158/1940-6207.CAPR-17-0349
Published: 30 April 2018
View article titled, Pharmacological TLR4 Antagonism Using Topical Resatorvid Blocks Solar UV-Induced Skin Tumorigenesis in SKH-1 Mice
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Includes: Supplementary data
Journal Articles

The Prolyl Isomerase Pin1 Is a Novel Target of 6,7,4′-Trihydroxyisoflavone for Suppressing Esophageal Cancer Growth

Tae-Gyu Lim, Sung-Young Lee, Zhaoheng Duan, Mee-Hyun Lee, Hanyong Chen, Fangfang Liu, Kangdong Liu, Sung Keun Jung, Dong Joon Kim, Ann M. Bode, Ki Won Lee, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2017) 10 (5): 308–318.
https://doi.org/10.1158/1940-6207.CAPR-16-0318
Published: 01 May 2017
View article titled, The Prolyl Isomerase Pin1 Is a Novel Target of 6,7,4′-Trihydroxyisoflavone for Suppressing Esophageal Cancer Growth
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Includes: Supplementary data
Journal Articles

Inhibition of Akt Enhances the Chemopreventive Effects of Topical Rapamycin in Mouse Skin

Sally E. Dickinson, Jaroslav Janda, Jane Criswell, Karen Blohm-Mangone, Erik R. Olson, Zhonglin Liu, Christy Barber, Emanuel F. Petricoin, III, Valerie S. Calvert, Janine Einspahr, Jesse E. Dickinson, Steven P. Stratton, Clara Curiel-Lewandrowski, Kathylynn Saboda, Chengcheng Hu, Ann M. Bode, Zigang Dong, David S. Alberts, G. Timothy Bowden
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2016) 9 (3): 215–224.
https://doi.org/10.1158/1940-6207.CAPR-15-0419
Published: 01 March 2016
View article titled, Inhibition of Akt Enhances the Chemopreventive Effects of Topical Rapamycin in Mouse Skin
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Includes: Supplementary data
Journal Articles

Transforming Cancer Prevention through Precision Medicine and Immune-oncology

Thomas W. Kensler, Avrum Spira, Judy E. Garber, Eva Szabo, J. Jack Lee, Zigang Dong, Andrew J. Dannenberg, William N. Hait, Elizabeth Blackburn, Nancy E. Davidson, Margaret Foti, Scott M. Lippman
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2016) 9 (1): 2–10.
https://doi.org/10.1158/1940-6207.CAPR-15-0406
Published: 06 January 2016
View article titled, Transforming Cancer Prevention through Precision Medicine and Immune-oncology
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Journal Articles

Cancer Prevention Research in China

Siwang Yu, Chung S. Yang, Junyao Li, Weicheng You, Jianguo Chen, Ya Cao, Zigang Dong, Youlin Qiao
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (8): 662–674.
https://doi.org/10.1158/1940-6207.CAPR-14-0469
Published: 03 August 2015
View article titled, Cancer Prevention Research in China
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Includes: Supplementary data
Journal Articles

Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin

Yira Bermudez, Steven P. Stratton, Clara Curiel-Lewandrowski, James Warneke, Chengcheng Hu, George T. Bowden, Sally E. Dickinson, Zigang Dong, Ann M. Bode, Kathylynn Saboda, Christine A. Brooks, Emanuel F. Petricoin, III, Craig A. Hurst, David S. Alberts, Janine G. Einspahr
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (8): 720–728.
https://doi.org/10.1158/1940-6207.CAPR-14-0407
Published: 03 August 2015
View article titled, Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin
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Includes: Supplementary data
Journal Articles

Toxic Phytochemicals and Their Potential Risks for Human Cancer

Ann M. Bode, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (1): 1–8.
https://doi.org/10.1158/1940-6207.CAPR-14-0160
Published: 08 January 2015
View article titled, Toxic Phytochemicals and Their Potential Risks for Human Cancer
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Journal Articles

Abstract CN07-02: Molecularly targeted cancer prevention: From discovery to medicine

Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (10_Supplement): CN07-02.
https://doi.org/10.1158/1940-6207.PREV-11-CN07-02
Published: 23 October 2014
View article titled, Abstract CN07-02: Molecularly targeted cancer prevention: From discovery to medicine
Journal Articles

Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis

Ge Yang, Yang Fu, Margarita Malakhova, Igor Kurinov, Feng Zhu, Ke Yao, Haitao Li, Hanyong Chen, Wei Li, Do Young Lim, Yuqiao Sheng, Ann M. Bode, Ziming Dong, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (10): 1056–1066.
https://doi.org/10.1158/1940-6207.CAPR-14-0141
Published: 02 October 2014
View article titled, Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis
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Includes: Supplementary data
Journal Articles

Kaempferol Targets RSK2 and MSK1 to Suppress UV Radiation-Induced Skin Cancer

Ke Yao, Hanyong Chen, Kangdong Liu, Alyssa Langfald, Ge Yang, Yi Zhang, Dong Hoon Yu, Myoung Ok Kim, Mee-Hyun Lee, Haitao Li, Ki Beom Bae, Hong-Gyum Kim, Wei-Ya Ma, Ann M. Bode, Ziming Dong, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (9): 958–967.
https://doi.org/10.1158/1940-6207.CAPR-14-0126
Published: 01 September 2014
View article titled, Kaempferol Targets RSK2 and MSK1 to Suppress UV Radiation-Induced Skin Cancer
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Includes: Supplementary data
Journal Articles

Abstract ED01-03: Forward and backward cell transformation induced by microenvironment factors: A tribute to Allan H. Conney

Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2013) 6 (11_Supplement): ED01-03.
https://doi.org/10.1158/1940-6215.PREV-13-ED01-03
Published: 28 August 2014
View article titled, Abstract ED01-03: Forward and backward cell transformation induced by microenvironment factors: A tribute to Allan H. Conney
Journal Articles

(+)-2-(1-Hydroxyl-4-Oxocyclohexyl) Ethyl Caffeate Suppresses Solar UV-Induced Skin Carcinogenesis by Targeting PI3K, ERK1/2, and p38

Do Young Lim, Mee-Hyun Lee, Seung Ho Shin, Hanyoung Chen, Joohyun Ryu, Lei Shan, Honglin Li, Ann M. Bode, Wei-Dong Zhang, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (8): 856–865.
https://doi.org/10.1158/1940-6207.CAPR-13-0286
Published: 03 August 2014
View article titled, (+)-2-(1-Hydroxyl-4-Oxocyclohexyl) Ethyl Caffeate Suppresses Solar UV-Induced Skin Carcinogenesis by Targeting PI3K, ERK1/2, and p38
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Includes: Supplementary data
Journal Articles

Curcumin Suppresses Proliferation of Colon Cancer Cells by Targeting CDK2

Tae-Gyu Lim, Sung-Young Lee, Zunnan Huang, Do Young Lim, Hanyong Chen, Sung Keun Jung, Ann M. Bode, Ki Won Lee, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (4): 466–474.
https://doi.org/10.1158/1940-6207.CAPR-13-0387
Published: 01 April 2014
View article titled, Curcumin Suppresses Proliferation of Colon Cancer Cells by Targeting CDK2
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Includes: Supplementary data
Journal Articles

Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K

Mi-Sung Kim, Jong-Eun Kim, Do Young Lim, Zunnan Huang, Hanyong Chen, Alyssa Langfald, Ronald A. Lubet, Clinton J. Grubbs, Zigang Dong, Ann M. Bode
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (2): 236–245.
https://doi.org/10.1158/1940-6207.CAPR-13-0288
Published: 06 February 2014
View article titled, Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K
Open the PDF for Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K in another window
Includes: Supplementary data
Journal Articles

Abstract CN08-01: Computerized approaches to molecularly-designed drugs and target identification for cancer prevention

Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2012) 5 (11_Supplement): CN08-01.
https://doi.org/10.1158/1940-6207.PREV-12-CN08-01
Published: 23 January 2014
View article titled, Abstract CN08-01: Computerized approaches to molecularly-designed drugs and target identification for cancer prevention
Journal Articles

Abstract B55: Involvement of RSK2 in human skin cancer

Cheol-Jung Lee, Mee Hyun Lee, Ke Yao, Hye Suk Lee, Ann M. Bode, Zigang Dong, Yong Yeon Cho
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2012) 5 (11_Supplement): B55.
https://doi.org/10.1158/1940-6207.PREV-12-B55
Published: 23 January 2014
View article titled, Abstract B55: Involvement of RSK2 in human skin cancer
Journal Articles

A Derivative of Chrysin Suppresses Two-Stage Skin Carcinogenesis by Inhibiting Mitogen- and Stress-Activated Kinase 1

Haidan Liu, Joonsung Hwang, Wei Li, Tae Woong Choi, Kangdong Liu, Zunnan Huang, Jae-Hyuk Jang, N.R. Thimmegowda, Ki Won Lee, In-Ja Ryoo, Jong-Seog Ahn, Ann M. Bode, Xinmin Zhou, Yifeng Yang, Raymond L. Erikson, Bo-Yeon Kim, Zigang Dong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (1): 74–85.
https://doi.org/10.1158/1940-6207.CAPR-13-0133
Published: 07 January 2014
View article titled, A Derivative of Chrysin Suppresses Two-Stage Skin Carcinogenesis by Inhibiting Mitogen- and Stress-Activated Kinase 1
Open the PDF for A Derivative of Chrysin Suppresses Two-Stage Skin Carcinogenesis by Inhibiting Mitogen- and Stress-Activated Kinase 1 in another window
Includes: Supplementary data