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Shivendra V. Singh
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Journal Articles

Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer

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Jian-Min Yuan, Thomas W. Kensler, Sanja Dacic, Douglas J. Hartman, Renwei Wang, Paula A. Balogh, Pamela Sufka, Melissa A. Turner, Kimberly Fuhrer, Lindsey Seigh, Yen Thi-Hai Pham, Jennifer Adams-Haduch, Giuseppe Valacchi, Shivendra V. Singh, James G. Herman, David O. Wilson
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) OF1–OF11.
https://doi.org/10.1158/1940-6207.CAPR-24-0386
Published: 20 March 2025
View articletitled, Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer
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Includes: Supplementary data
Journal Articles

Withaferin A Inhibits Fatty Acid Synthesis in Rat Mammary Tumors

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Krishna B. Singh, Eun-Ryeong Hahm, Su-Hyeong Kim, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2023) 16 (1): 5–16.
https://doi.org/10.1158/1940-6207.CAPR-22-0193
Published: 04 January 2023
View articletitled, Withaferin A Inhibits Fatty Acid Synthesis in Rat Mammary Tumors
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Includes: Supplementary data
Journal Articles

The Role of Forkhead Box Q1 Transcription Factor in Anticancer Effects of Withaferin A in Breast Cancer

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Su-Hyeong Kim, Krishna B. Singh, Eun-Ryeong Hahm, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2021) 14 (4): 421–432.
https://doi.org/10.1158/1940-6207.CAPR-20-0590
Published: 01 April 2021
View articletitled, The Role of Forkhead Box Q1 Transcription Factor in Anticancer Effects of Withaferin A in Breast Cancer
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Includes: Supplementary data
Journal Articles

A Comprehensive Review and Perspective on Anticancer Mechanisms of Withaferin A in Breast Cancer

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Eun-Ryeong Hahm, Su-Hyeong Kim, Krishna B. Singh, Kamayani Singh, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2020) 13 (9): 721–734.
https://doi.org/10.1158/1940-6207.CAPR-20-0259
Published: 02 September 2020
View articletitled, A Comprehensive Review and Perspective on Anticancer Mechanisms of Withaferin A in Breast Cancer
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Journal Articles

The Role of Lysosome-associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane

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Eun-Ryeong Hahm, Krishna B. Singh, Su-Hyeong Kim, Anna A. Powolny, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2020) 13 (8): 661–672.
https://doi.org/10.1158/1940-6207.CAPR-20-0054
Published: 04 August 2020
View articletitled, The Role of Lysosome-associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane
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Includes: Supplementary data
Journal Articles

Role of Krüppel-like Factor 4-p21CIP1 Axis in Breast Cancer Stem-like Cell Inhibition by Benzyl Isothiocyanate

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Su-Hyeong Kim, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2019) 12 (3): 125–134.
https://doi.org/10.1158/1940-6207.CAPR-18-0393
Published: 04 March 2019
View articletitled, Role of Krüppel-like Factor 4-p21CIP1 Axis in Breast Cancer Stem-like Cell Inhibition by Benzyl Isothiocyanate
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Journal Articles

Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi

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Shawn Tahata, Shivendra V. Singh, Yan Lin, Eun-Ryeong Hahm, Jan H. Beumer, Susan M. Christner, Uma N. Rao, Cindy Sander, Ahmad A. Tarhini, Hussein Tawbi, Laura K. Ferris, Melissa Wilson, Amy Rose, Catherine M. Dietz, Ellen Hughes, Jed W. Fahey, Sancy A. Leachman, Pamela B. Cassidy, Lisa H. Butterfield, Hassane M. Zarour, John M. Kirkwood
Journal: Cancer Prevention Research
Series: Author Choice
Cancer Prev Res (Phila) (2018) 11 (7): 429–438.
https://doi.org/10.1158/1940-6207.CAPR-17-0268
Published: 01 July 2018
View articletitled, Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi
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Includes: Supplementary data
Journal Articles

Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate

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Krishna B. Singh, Eun-Ryeong Hahm, Lora H. Rigatti, Daniel P. Normolle, Jian-Min Yuan, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2018) 11 (6): 337–346.
https://doi.org/10.1158/1940-6207.CAPR-17-0389
Published: 31 May 2018
View articletitled, Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate
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Journal Articles

Fatty Acid Synthesis Intermediates Represent Novel Noninvasive Biomarkers of Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate

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Krishna B. Singh, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2017) 10 (5): 279–289.
https://doi.org/10.1158/1940-6207.CAPR-17-0001
Published: 01 May 2017
View articletitled, Fatty Acid Synthesis Intermediates Represent Novel Noninvasive Biomarkers of Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate
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Journal Articles

CXCR4 Is a Novel Target of Cancer Chemopreventative Isothiocyanates in Prostate Cancer Cells

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Kozue Sakao, Avani R. Vyas, Sreenivasa R. Chinni, Ali I. Amjad, Rahul Parikh, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (5): 365–374.
https://doi.org/10.1158/1940-6207.CAPR-14-0386
Published: 30 April 2015
View articletitled, CXCR4 Is a Novel Target of Cancer Chemopreventative Isothiocyanates in Prostate Cancer Cells
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Includes: Supplementary data
Journal Articles

Mammary Cancer Chemoprevention by Withaferin A Is Accompanied by In Vivo Suppression of Self-Renewal of Cancer Stem Cells

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Su-Hyeong Kim, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (7): 738–747.
https://doi.org/10.1158/1940-6207.CAPR-13-0445
Published: 01 July 2014
View articletitled, Mammary Cancer Chemoprevention by Withaferin A Is Accompanied by In Vivo Suppression of Self-Renewal of Cancer Stem Cells
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Journal Articles

Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells In Vitro and In Vivo

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Su-Hyeong Kim, Anuradha Sehrawat, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2013) 6 (8): 782–790.
https://doi.org/10.1158/1940-6207.CAPR-13-0100
Published: 04 August 2013
View articletitled, Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells In Vitro and In Vivo
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Includes: Supplementary data
Journal Articles

Benzyl Isothiocyanate Inhibits Epithelial-Mesenchymal Transition in Cultured and Xenografted Human Breast Cancer Cells

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Anuradha Sehrawat, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (7): 1107–1117.
https://doi.org/10.1158/1940-6207.CAPR-10-0306
Published: 05 July 2011
View articletitled, Benzyl Isothiocyanate Inhibits Epithelial-Mesenchymal Transition in Cultured and Xenografted Human Breast Cancer Cells
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Includes: Supplementary data
Journal Articles

Garlic Constituent Diallyl Trisulfide Suppresses X-linked Inhibitor of Apoptosis Protein in Prostate Cancer Cells in Culture and In Vivo

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Su-Hyeong Kim, Ajay Bommareddy, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (6): 897–906.
https://doi.org/10.1158/1940-6207.CAPR-10-0323
Published: 01 June 2011
View articletitled, Garlic Constituent Diallyl Trisulfide Suppresses X-linked Inhibitor of Apoptosis Protein in Prostate Cancer Cells in Culture and In Vivo
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Journal Articles

Inhibition of EGFR-STAT3 Signaling with Erlotinib Prevents Carcinogenesis in a Chemically-Induced Mouse Model of Oral Squamous Cell Carcinoma

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Rebecca J. Leeman-Neill, Raja R. Seethala, Shivendra V. Singh, Maria L. Freilino, Joseph S. Bednash, Sufi M. Thomas, Mary C. Panahandeh, William E. Gooding, Sonali C. Joyce, Mark W. Lingen, Daniel B. Neill, Jennifer R. Grandis
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (2): 230–237.
https://doi.org/10.1158/1940-6207.CAPR-10-0249
Published: 02 February 2011
View articletitled, Inhibition of EGFR-STAT3 Signaling with Erlotinib Prevents Carcinogenesis in a Chemically-Induced Mouse Model of Oral Squamous Cell Carcinoma
Open the PDF for Inhibition of EGFR-STAT3 Signaling with Erlotinib Prevents Carcinogenesis in a Chemically-Induced Mouse Model of Oral Squamous Cell Carcinoma in another window
Journal Articles

Diallyl Trisulfide Inhibits Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells in Culture and In vivo

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Kumar Chandra-Kuntal, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (11): 1473–1483.
https://doi.org/10.1158/1940-6207.CAPR-10-0123
Published: 08 November 2010
View articletitled, Diallyl Trisulfide Inhibits Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells in Culture and In vivo
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Journal Articles

p53-Independent Apoptosis by Benzyl Isothiocyanate in Human Breast Cancer Cells Is Mediated by Suppression of XIAP Expression

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Su-Hyeong Kim, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (6): 718–726.
https://doi.org/10.1158/1940-6207.CAPR-10-0048
Published: 02 June 2010
View articletitled, p53-Independent Apoptosis by Benzyl Isothiocyanate in Human Breast Cancer Cells Is Mediated by Suppression of XIAP Expression
Open the PDF for p53-Independent Apoptosis by Benzyl Isothiocyanate in Human Breast Cancer Cells Is Mediated by Suppression of XIAP Expression in another window
Journal Articles

Sulforaphane Inhibits Constitutive and Interleukin-6–Induced Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells

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Eun-Ryeong Hahm, Shivendra V. Singh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (4): 484–494.
https://doi.org/10.1158/1940-6207.CAPR-09-0250
Published: 04 April 2010
View articletitled, Sulforaphane Inhibits Constitutive and Interleukin-6–Induced Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells
Open the PDF for Sulforaphane Inhibits Constitutive and Interleukin-6–Induced Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells in another window