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Ronald A. Lubet
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Journal Articles

PRIMARY PREVENTION AND INTERCEPTION STUDIES IN RAS-MUTATED TUMOR MODELS EMPLOYING SMALL MOLECULES OR VACCINES

Konstantin H. Dragnev, Ronald A. Lubet, Mark Steven. Miller, Shizuko Sei, Jennifer T. Fox, Ming You
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) CAPR-23-0027.
https://doi.org/10.1158/1940-6207.CAPR-23-0027
Published: 19 July 2023
View article titled, PRIMARY PREVENTION AND INTERCEPTION STUDIES IN RAS-MUTATED TUMOR MODELS EMPLOYING SMALL MOLECULES OR VACCINES
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Includes: Supplementary data
Journal Articles

Abstract IA015: Immunoprevention of triple negative breast cancer by TOP2A derived peptide vaccination

Sang Beom Lee, Jing Pan, Donghai Xiong, Katie Palen, Bryon Johnson, Jeffrey E. Green, Shizuko Sei, Robert H. Shoemaker, Ronald A. Lubet, Yian Wang, Ming You
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2022) 15 (12_Supplement_2): IA015.
https://doi.org/10.1158/1940-6215.TACPAD22-IA015
Published: 01 December 2022
View article titled, Abstract IA015: Immunoprevention of triple negative breast cancer by TOP2A derived peptide vaccination
Journal Articles

COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes

Denise L. Cecil, Ekram A. Gad, Lauren R. Corulli, Nicholas Drovetto, Ronald A. Lubet, Mary L. Disis
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2022) 15 (4): 225–231.
https://doi.org/10.1158/1940-6207.CAPR-21-0227
Published: 01 April 2022
View article titled, COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes
Open the PDF for COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes in another window
Includes: Supplementary data
Journal Articles

Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically Induced Cancers

Ronald A. Lubet, Brandy M. Heckman-Stoddard, Jennifer T. Fox, Fariba Moeinpour, M. Margaret Juliana, Robert H. Shoemaker, Clinton J. Grubbs
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2020) 13 (3): 283–290.
https://doi.org/10.1158/1940-6207.CAPR-19-0318
Published: 04 March 2020
View article titled, Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically Induced Cancers
Open the PDF for Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically Induced Cancers in another window
Includes: Supplementary data
Journal Articles

Combination of Erlotinib and Naproxen Employing Pulsatile or Intermittent Dosing Profoundly Inhibits Urinary Bladder Cancers

Altaf Mohammed, Mark Steven Miller, Ronald A. Lubet, Chen S. Suen, Shizuko Sei, Robert H. Shoemaker, Margaret M. Juliana, Fariba L. Moeinpour, Clinton J. Grubbs
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2020) 13 (3): 273–282.
https://doi.org/10.1158/1940-6207.CAPR-19-0339
Published: 04 March 2020
View article titled, Combination of Erlotinib and Naproxen Employing Pulsatile or Intermittent Dosing Profoundly Inhibits Urinary Bladder Cancers
Open the PDF for Combination of Erlotinib and Naproxen Employing Pulsatile or Intermittent Dosing Profoundly Inhibits Urinary Bladder Cancers in another window
Includes: Supplementary data
Journal Articles

Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma

Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Yuting Zhang, Anil Singh, Laura Biddick, Qian Li, Stanley Lightfoot, Vernon E. Steele, Ronald A. Lubet, Chen S. Suen, Mark Steven Miller, Shizuko Sei, Chinthalapally V. Rao
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2019) 12 (11): 751–762.
https://doi.org/10.1158/1940-6207.CAPR-19-0312
Published: 01 November 2019
View article titled, Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma
Open the PDF for Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma in another window
Includes: Supplementary data
Journal Articles

Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents

Ronald A. Lubet, Richard D. Beger, Mark Steven Miller, John Luster, Harold E. Seifried, Clinton J. Grubbs
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2018) 11 (12): 831–840.
https://doi.org/10.1158/1940-6207.CAPR-18-0116
Published: 10 December 2018
View article titled, Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
Open the PDF for Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents in another window
Includes: Supplementary data
Journal Articles

Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression

Ronald A. Lubet, Vernon E. Steele, Robert H. Shoemaker, Clinton J. Grubbs
Journal: Cancer Prevention Research
Series: Author Choice
Cancer Prev Res (Phila) (2018) 11 (10): 595–606.
https://doi.org/10.1158/1940-6207.CAPR-18-0084
Published: 02 October 2018
View article titled, Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression
Open the PDF for Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression in another window
Includes: Supplementary data
Journal Articles

5MeCDDO Blocks Metabolic Activation but not Progression of Breast, Intestine, and Tongue Cancers. Is Antioxidant Response Element a Prevention Target?

Ronald A. Lubet, Reid Townsend, Margie L. Clapper, M. Margaret Juliana, Vernon E. Steele, David L. McCormick, Clinton J. Grubbs
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2016) 9 (7): 616–623.
https://doi.org/10.1158/1940-6207.CAPR-15-0294
Published: 30 June 2016
View article titled, 5MeCDDO Blocks Metabolic Activation but not Progression of Breast, Intestine, and Tongue Cancers. Is Antioxidant Response Element a Prevention Target?
Open the PDF for 5MeCDDO Blocks Metabolic Activation but not Progression of Breast, Intestine, and Tongue Cancers. Is Antioxidant Response Element a Prevention Target? in another window
Includes: Supplementary data
Journal Articles

Abstract PR09: Intermittent dosing regimens maintain efficacy of several cancer preventing drugs

Vernon E. Steele, Clinton J. Grubbs, Ronald A. Lubet
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (10_Supplement): PR09.
https://doi.org/10.1158/1940-6215.PREV-14-PR09
Published: 02 October 2015
View article titled, Abstract PR09: Intermittent dosing regimens maintain efficacy of several cancer preventing drugs
Journal Articles

Prevention of Chemically Induced Urinary Bladder Cancers by Naproxen: Protocols to Reduce Gastric Toxicity in Humans Do Not Alter Preventive Efficacy

Ronald A. Lubet, James M. Scheiman, Ann Bode, Jonathan White, Lori Minasian, M. Margaret Juliana, Daniel L. Boring, Vernon E. Steele, Clinton J. Grubbs
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (4): 296–302.
https://doi.org/10.1158/1940-6207.CAPR-14-0347
Published: 31 March 2015
View article titled, Prevention of Chemically Induced Urinary Bladder Cancers by Naproxen: Protocols to Reduce Gastric Toxicity in Humans Do Not Alter Preventive Efficacy
Open the PDF for Prevention of Chemically Induced Urinary Bladder Cancers by Naproxen: Protocols to Reduce Gastric Toxicity in Humans Do Not Alter Preventive Efficacy in another window
Includes: Supplementary data
Journal Articles

Enhanced Antitumor Activity of 3-Bromopyruvate in Combination with Rapamycin In Vivo and In Vitro

Qi Zhang, Jing Pan, Ronald A. Lubet, Steven M. Komas, Balaraman Kalyanaraman, Yian Wang, Ming You
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (4): 318–326.
https://doi.org/10.1158/1940-6207.CAPR-14-0142
Published: 31 March 2015
View article titled, Enhanced Antitumor Activity of 3-Bromopyruvate in Combination with Rapamycin <em>In Vivo</em> and <em>In Vitro</em>
Open the PDF for Enhanced Antitumor Activity of 3-Bromopyruvate in Combination with Rapamycin <em>In Vivo</em> and <em>In Vitro</em> in another window
Includes: Supplementary data
Journal Articles

Lack of Effect of Metformin on Mammary Carcinogenesis in Nondiabetic Rat and Mouse Models

Matthew D. Thompson, Clinton J. Grubbs, Ann M. Bode, Joel M. Reid, Renee McGovern, Philip S. Bernard, Inge J. Stijleman, Jeffrey E. Green, Christina Bennett, M. Margaret Juliana, Fariba Moeinpour, Vernon E. Steele, Ronald A. Lubet
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (3): 231–239.
https://doi.org/10.1158/1940-6207.CAPR-14-0181-T
Published: 05 March 2015
View article titled, Lack of Effect of Metformin on Mammary Carcinogenesis in Nondiabetic Rat and Mouse Models
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Journal Articles

Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function

Jing Pan, Qi Zhang, Qian Liu, Steven M. Komas, Balaraman Kalyanaraman, Ronald A. Lubet, Yian Wang, Ming You
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (11): 1149–1159.
https://doi.org/10.1158/1940-6207.CAPR-14-0091
Published: 02 November 2014
View article titled, Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function
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Journal Articles

Abstract B49: Use of MMTV-Neu/P53 KO transgenic mice to screen for potential chemopreventive agents

Ronald A. Lubet, Clinton J. Grubbs, Margaret Juliana, Ann Bode, Vernon E. Steele, Kenneth Iwata
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (12_Supplement): B49.
https://doi.org/10.1158/1940-6207.PREV-10-B49
Published: 24 October 2014
View article titled, Abstract B49: Use of MMTV-Neu/P53 KO transgenic mice to screen for potential chemopreventive agents
Journal Articles

Abstract B48: Lack of efficacy of the anti-diabetic drug metformin in the ER+ methylnitrosourea (MNU)-induced and the ER- MMTV-Neu/p53KO models of mammary cancer

Ronald A. Lubet, Ann M. Bode, Vernon E. Steele, Clinton J. Grubbs
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (12_Supplement): B48.
https://doi.org/10.1158/1940-6207.PREV-10-B48
Published: 24 October 2014
View article titled, Abstract B48: Lack of efficacy of the anti-diabetic drug metformin in the ER+ methylnitrosourea (MNU)-induced and the ER<sup>-</sup> MMTV-Neu/p53KO models of mammary cancer
Journal Articles

Abstract B51: Prevention of mouse lung tumors by combinations containing SAHA and atorvastin

Michael A. Pereira, Bruce C. Casto, Ronald A. Lubet, Veron E. Steele
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (12_Supplement): B51.
https://doi.org/10.1158/1940-6207.PREV-10-B51
Published: 24 October 2014
View article titled, Abstract B51: Prevention of mouse lung tumors by combinations containing SAHA and atorvastin
Journal Articles

Abstract A106: Efficacy of EGFr inhibitors gefitinib on development of OH-BBN-induced rat bladder tumors: Dose dependency and modulation of biomarkers

Yian Lu, Ronald A. Lubet, Ming You, Ann Bode, Vernon E. Steele, Reid Townsend, Clinton J. Grubbs
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (12_Supplement): A106.
https://doi.org/10.1158/1940-6207.PREV-10-A106
Published: 24 October 2014
View article titled, Abstract A106: Efficacy of EGFr inhibitors gefitinib on development of OH-BBN-induced rat bladder tumors: Dose dependency and modulation of biomarkers
Journal Articles

Abstract A101: Dose-related suppression of rat oral carcinogenesis by the EGF receptor-tyrosine kinase inhibitor, gefitinib

Thomas L. Horn, William D. Johnson, Ronald A. Lubet, Vernon E. Steele, David L. McCormick
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (12_Supplement): A101.
https://doi.org/10.1158/1940-6207.PREV-10-A101
Published: 24 October 2014
View article titled, Abstract A101: Dose-related suppression of rat oral carcinogenesis by the EGF receptor-tyrosine kinase inhibitor, gefitinib
Journal Articles

Abstract A33: Identification of potential immunologic targets in mice and man that are overexpressed in colon adenomas and colorectal cancer

Elizabeth K. Broussard, David K. Pritchard, Ronald A. Lubet, Mary L. Disis
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (12_Supplement): A33.
https://doi.org/10.1158/1940-6207.PREV-10-A33
Published: 24 October 2014
View article titled, Abstract A33: Identification of potential immunologic targets in mice and man that are overexpressed in colon adenomas and colorectal cancer