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Journal Articles

COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes

Denise L. Cecil, Ekram A. Gad, Lauren R. Corulli, Nicholas Drovetto, Ronald A. Lubet, Mary L. Disis

Cancer Prev Res (Phila) (2022) 15 (4): 225–231.

DOI: https://doi.org/10.1158/1940-6207.CAPR-21-0227

Published: 01 April 2022

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Includes: Supplementary data

Journal Articles

Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically Induced Cancers

Ronald A. Lubet, Brandy M. Heckman-Stoddard, Jennifer T. Fox, Fariba Moeinpour, M. Margaret Juliana, Robert H. Shoemaker, Clinton J. Grubbs

Cancer Prev Res (Phila) (2020) 13 (3): 283–290.

DOI: https://doi.org/10.1158/1940-6207.CAPR-19-0318

Published: 04 March 2020

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Includes: Supplementary data

Journal Articles

Combination of Erlotinib and Naproxen Employing Pulsatile or Intermittent Dosing Profoundly Inhibits Urinary Bladder Cancers

Altaf Mohammed, Mark Steven Miller, Ronald A. Lubet, Chen S. Suen, Shizuko Sei, Robert H. Shoemaker, Margaret M. Juliana, Fariba L. Moeinpour, Clinton J. Grubbs

Cancer Prev Res (Phila) (2020) 13 (3): 273–282.

DOI: https://doi.org/10.1158/1940-6207.CAPR-19-0339

Published: 04 March 2020

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Includes: Supplementary data

Journal Articles

Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma

Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Yuting Zhang, Anil Singh, Laura Biddick, Qian Li, Stanley Lightfoot, Vernon E. Steele, Ronald A. Lubet, Chen S. Suen, Mark Steven Miller, Shizuko Sei, Chinthalapally V. Rao

Cancer Prev Res (Phila) (2019) 12 (11): 751–762.

DOI: https://doi.org/10.1158/1940-6207.CAPR-19-0312

Published: 01 November 2019

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Includes: Supplementary data

Journal Articles

Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents

Ronald A. Lubet, Richard D. Beger, Mark Steven Miller, John Luster, Harold E. Seifried, Clinton J. Grubbs

Cancer Prev Res (Phila) (2018) 11 (12): 831–840.

DOI: https://doi.org/10.1158/1940-6207.CAPR-18-0116

Published: 10 December 2018

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Includes: Supplementary data

Journal Articles

Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression

Ronald A. Lubet, Vernon E. Steele, Robert H. Shoemaker, Clinton J. Grubbs

Cancer Prev Res (Phila) (2018) 11 (10): 595–606.

DOI: https://doi.org/10.1158/1940-6207.CAPR-18-0084

Published: 02 October 2018

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Includes: Supplementary data

Journal Articles

5MeCDDO Blocks Metabolic Activation but not Progression of Breast, Intestine, and Tongue Cancers. Is Antioxidant Response Element a Prevention Target?

Ronald A. Lubet, Reid Townsend, Margie L. Clapper, M. Margaret Juliana, Vernon E. Steele, David L. McCormick, Clinton J. Grubbs

Cancer Prev Res (Phila) (2016) 9 (7): 616–623.

DOI: https://doi.org/10.1158/1940-6207.CAPR-15-0294

Published: 30 June 2016

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Includes: Supplementary data

Journal Articles

Abstract PR09: Intermittent dosing regimens maintain efficacy of several cancer preventing drugs

Vernon E. Steele, Clinton J. Grubbs, Ronald A. Lubet

Cancer Prev Res (Phila) (2015) 8 (10_Supplement): PR09.

DOI: https://doi.org/10.1158/1940-6215.PREV-14-PR09

Published: 02 October 2015

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Journal Articles

Prevention of Chemically Induced Urinary Bladder Cancers by Naproxen: Protocols to Reduce Gastric Toxicity in Humans Do Not Alter Preventive Efficacy

Ronald A. Lubet, James M. Scheiman, Ann Bode, Jonathan White, Lori Minasian, M. Margaret Juliana, Daniel L. Boring, Vernon E. Steele, Clinton J. Grubbs

Cancer Prev Res (Phila) (2015) 8 (4): 296–302.

DOI: https://doi.org/10.1158/1940-6207.CAPR-14-0347

Published: 31 March 2015

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Includes: Supplementary data

Journal Articles

Enhanced Antitumor Activity of 3-Bromopyruvate in Combination with Rapamycin In Vivo and In Vitro

Qi Zhang, Jing Pan, Ronald A. Lubet, Steven M. Komas, Balaraman Kalyanaraman, Yian Wang, Ming You

Cancer Prev Res (Phila) (2015) 8 (4): 318–326.

DOI: https://doi.org/10.1158/1940-6207.CAPR-14-0142

Published: 31 March 2015

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Includes: Supplementary data

Journal Articles

Lack of Effect of Metformin on Mammary Carcinogenesis in Nondiabetic Rat and Mouse Models

Matthew D. Thompson, Clinton J. Grubbs, Ann M. Bode, Joel M. Reid, Renee McGovern, Philip S. Bernard, Inge J. Stijleman, Jeffrey E. Green, Christina Bennett, M. Margaret Juliana, Fariba Moeinpour, Vernon E. Steele, Ronald A. Lubet

Cancer Prev Res (Phila) (2015) 8 (3): 231–239.

DOI: https://doi.org/10.1158/1940-6207.CAPR-14-0181-T

Published: 05 March 2015

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Journal Articles

Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function

Jing Pan, Qi Zhang, Qian Liu, Steven M. Komas, Balaraman Kalyanaraman, Ronald A. Lubet, Yian Wang, Ming You

Cancer Prev Res (Phila) (2014) 7 (11): 1149–1159.

DOI: https://doi.org/10.1158/1940-6207.CAPR-14-0091

Published: 02 November 2014

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Journal Articles

Abstract B49: Use of MMTV-Neu/P53 KO transgenic mice to screen for potential chemopreventive agents

Ronald A. Lubet, Clinton J. Grubbs, Margaret Juliana, Ann Bode, Vernon E. Steele, Kenneth Iwata

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): B49.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-B49

Published: 24 October 2014

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Journal Articles

Abstract B48: Lack of efficacy of the anti-diabetic drug metformin in the ER+ methylnitrosourea (MNU)-induced and the ER^- MMTV-Neu/p53KO models of mammary cancer

Ronald A. Lubet, Ann M. Bode, Vernon E. Steele, Clinton J. Grubbs

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): B48.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-B48

Published: 24 October 2014

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Journal Articles

Abstract B51: Prevention of mouse lung tumors by combinations containing SAHA and atorvastin

Michael A. Pereira, Bruce C. Casto, Ronald A. Lubet, Veron E. Steele

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): B51.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-B51

Published: 24 October 2014

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Journal Articles

Abstract A106: Efficacy of EGFr inhibitors gefitinib on development of OH-BBN-induced rat bladder tumors: Dose dependency and modulation of biomarkers

Yian Lu, Ronald A. Lubet, Ming You, Ann Bode, Vernon E. Steele, Reid Townsend, Clinton J. Grubbs

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): A106.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-A106

Published: 24 October 2014

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Journal Articles

Abstract A101: Dose-related suppression of rat oral carcinogenesis by the EGF receptor-tyrosine kinase inhibitor, gefitinib

Thomas L. Horn, William D. Johnson, Ronald A. Lubet, Vernon E. Steele, David L. McCormick

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): A101.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-A101

Published: 24 October 2014

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Journal Articles

Abstract A33: Identification of potential immunologic targets in mice and man that are overexpressed in colon adenomas and colorectal cancer

Elizabeth K. Broussard, David K. Pritchard, Ronald A. Lubet, Mary L. Disis

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): A33.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-A33

Published: 24 October 2014

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Journal Articles

Preventive Effects of NSAIDs, NO-NSAIDs, and NSAIDs Plus Difluoromethylornithine in a Chemically Induced Urinary Bladder Cancer Model

Holly L. Nicastro, Clinton J. Grubbs, M. Margaret Juliana, Ann M. Bode, Mi-Sung Kim, Yan Lu, Ming You, Ginger L. Milne, Daniel Boring, Vernon E. Steele, Ronald A. Lubet

Cancer Prev Res (Phila) (2014) 7 (2): 246–254.

DOI: https://doi.org/10.1158/1940-6207.CAPR-13-0164

Published: 06 February 2014

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Includes: Supplementary data

Journal Articles

Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K

Mi-Sung Kim, Jong-Eun Kim, Do Young Lim, Zunnan Huang, Hanyong Chen, Alyssa Langfald, Ronald A. Lubet, Clinton J. Grubbs, Zigang Dong, Ann M. Bode

Cancer Prev Res (Phila) (2014) 7 (2): 236–245.

DOI: https://doi.org/10.1158/1940-6207.CAPR-13-0288

Published: 06 February 2014

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Includes: Supplementary data

NARROW

COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes

Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically Induced Cancers

Combination of Erlotinib and Naproxen Employing Pulsatile or Intermittent Dosing Profoundly Inhibits Urinary Bladder Cancers

Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma

Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents

Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression

5MeCDDO Blocks Metabolic Activation but not Progression of Breast, Intestine, and Tongue Cancers. Is Antioxidant Response Element a Prevention Target?

Abstract PR09: Intermittent dosing regimens maintain efficacy of several cancer preventing drugs

Prevention of Chemically Induced Urinary Bladder Cancers by Naproxen: Protocols to Reduce Gastric Toxicity in Humans Do Not Alter Preventive Efficacy

Enhanced Antitumor Activity of 3-Bromopyruvate in Combination with Rapamycin In Vivo and In Vitro

Lack of Effect of Metformin on Mammary Carcinogenesis in Nondiabetic Rat and Mouse Models

Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function

Abstract B49: Use of MMTV-Neu/P53 KO transgenic mice to screen for potential chemopreventive agents

Abstract B48: Lack of efficacy of the anti-diabetic drug metformin in the ER+ methylnitrosourea (MNU)-induced and the ER^- MMTV-Neu/p53KO models of mammary cancer

Abstract B51: Prevention of mouse lung tumors by combinations containing SAHA and atorvastin

Abstract A106: Efficacy of EGFr inhibitors gefitinib on development of OH-BBN-induced rat bladder tumors: Dose dependency and modulation of biomarkers

Abstract A101: Dose-related suppression of rat oral carcinogenesis by the EGF receptor-tyrosine kinase inhibitor, gefitinib

Abstract A33: Identification of potential immunologic targets in mice and man that are overexpressed in colon adenomas and colorectal cancer

Preventive Effects of NSAIDs, NO-NSAIDs, and NSAIDs Plus Difluoromethylornithine in a Chemically Induced Urinary Bladder Cancer Model

Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K

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