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Journal Articles

Phase II Trial of Nelipepimut-S Peptide Vaccine in Women with Ductal Carcinoma In Situ

Anne E. O'Shea, Guy T. Clifton, Na Qiao, Brandy M. Heckman-Stoddard, Malgorzata Wojtowicz, Eileen Dimond, Isabelle Bedrosian, Diane Weber, Judy E. Garber, Alexander Husband, Ricardo Pastorello, J. Jack Lee, Mike Hernandez, Diane D. Liu, Lana A. Vornik, Powel H. Brown, Gheath Alatrash, George E. Peoples, Elizabeth A. Mittendorf

Cancer Prev Res (Phila) (2023) 16 (6): 333–341.

DOI: https://doi.org/10.1158/1940-6207.CAPR-22-0388

Published: 01 June 2023

View article titled, Phase II Trial of Nelipepimut-S Peptide Vaccine in Women with Ductal Carcinoma In Situ

Includes: Supplementary data

Journal Articles

Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer

Parijatham S. Thomas, Anisha B. Patel, J. Jack Lee, Diane D. Liu, Mike Hernandez, Miguel Muzzio, Alejandro Contreras, Valerie Sepeda, Carrie Mays, Diane Weber, Lana A. Vornik, Seema A. Khan, Eileen Dimond, Brandy M. Heckman-Stoddard, Marjorie Perloff, Powel H. Brown

Cancer Prev Res (Phila) (2023) 16 (1): 47–55.

DOI: https://doi.org/10.1158/1940-6207.CAPR-22-0210

Published: 04 January 2023

View article titled, Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer

Includes: Supplementary data

Journal Articles

Treatment Strategies and Mechanisms Associated with the Prevention of NASH-Associated HCC by a Toll-like Receptor 4 Inhibitor

Suet-Ying Kwan, Alyssa N. Slayden, Aubrey R. Coronado, Rosamaria C. Marquez, Huiqin Chen, Peng Wei, Michelle I. Savage, Lana A. Vornik, Jennifer T. Fox, Shizuko Sei, Dong Liang, Heather L. Stevenson, Gregory K. Wilkerson, Mihai Gagea, Powel H. Brown, Laura Beretta

Cancer Prev Res (Phila) (2023) 16 (1): 17–28.

DOI: https://doi.org/10.1158/1940-6207.CAPR-22-0332

Published: 04 January 2023

View article titled, Treatment Strategies and Mechanisms Associated with the Prevention of NASH-Associated HCC by a Toll-like Receptor 4 Inhibitor

Includes: Supplementary data

Journal Articles

Abstract IA017: Targeting the mTOR pathway for the prevention of triple-negative breast cancer

Powel H. Brown, Abhijit Mazumdar, William Tahaney, Jamal Hill, Yun Zhang, Sumankalai Ramachandran, Jitesh Kawedia, Jing Qian, Alejandra Contreras, Michelle Savage, Lana Vornik

Cancer Prev Res (Phila) (2023) 16 (1_Supplement): IA017.

DOI: https://doi.org/10.1158/1940-6215.PrecPrev22-IA017

Published: 01 January 2023

View article titled, Abstract IA017: Targeting the mTOR pathway for the prevention of triple-negative breast cancer

Journal Articles

Abstract A012: Repurposing of the macrolide antibiotic clarithromycin for the prevention of lung cancer

Seyed Javad Moghaddam, Tabish Hussain, Melody Zarghooni, Walter V. Velasco, Linda Phan, Michelle I. Savage, Jennifer T. Fox, Shizuko Sei, Powel H. Brown, C. Marcelo Aldaz

Cancer Prev Res (Phila) (2022) 15 (12_Supplement_2): A012.

DOI: https://doi.org/10.1158/1940-6215.TACPAD22-A012

Published: 01 December 2022

View article titled, Abstract A012: Repurposing of the macrolide antibiotic clarithromycin for the prevention of lung cancer

Journal Articles

Abstract IA013: Preclinical testing of CD73 inhibitors for pancreatic cancer immunoprevention

Lincoln Ballew, Kanchan Singh, Vidhi Chandra, Tingting Mills, Erika Y. Faraoni, Victoria Mota, Trent Clark, Lana Vornik, Michelle I. Savage, Shizuko Sei, Altaf Mohammed, Holger K. Eltzschig, Powel H. Brown, Florencia McAllister, Jennifer M. Bailey-Lundberg

Cancer Prev Res (Phila) (2022) 15 (12_Supplement_2): IA013.

DOI: https://doi.org/10.1158/1940-6215.TACPAD22-IA013

Published: 01 December 2022

View article titled, Abstract IA013: Preclinical testing of CD73 inhibitors for pancreatic cancer immunoprevention

Journal Articles

Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer

Abhijit Mazumdar, William M. Tahaney, Jamal L. Hill, Yun Zhang, Sumankalai Ramachandran, Jitesh Kawedia, Jing Qian, Alejandro Contreras, Michelle I. Savage, Lana A. Vornik, Shizuko Sei, Altaf Mohammed, Powel H. Brown

Cancer Prev Res (Phila) (2022) 15 (12): 791–802.

DOI: https://doi.org/10.1158/1940-6207.CAPR-22-0106

Published: 01 December 2022

View article titled, Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer

Includes: Supplementary data

Journal Articles

Lessons from the Failure to Complete a Trial of Denosumab in Women With a Pathogenic BRCA1/2 Variant Scheduling Risk-Reducing Salpingo-Oophorectomy

Meghna S. Trivedi, Nadir Arber, Eitan Friedman, Judy E. Garber, Kevin Holcomb, Neil S. Horowitz, Jason D. Wright, J. Jack Lee, Lana A. Vornik, Saba Abutaseh, Tawana Castile, Edward R. Sauter, Eileen Dimond, Brandy M. Heckman-Stoddard, Margaret House, Goli Samimi, Powel H. Brown, Katherine D. Crew

Cancer Prev Res (Phila) (2022) 15 (11): 721–726.

DOI: https://doi.org/10.1158/1940-6207.CAPR-22-0051

Published: 01 November 2022

View article titled, Lessons from the Failure to Complete a Trial of Denosumab in Women With a Pathogenic BRCA1/2 Variant Scheduling Risk-Reducing Salpingo-Oophorectomy

Journal Articles

Optimization of Erlotinib Plus Sulindac Dosing Regimens for Intestinal Cancer Prevention in an Apc-Mutant Model of Familial Adenomatous Polyposis (FAP)

Ahmet M. Ulusan, Praveen Rajendran, Wan Mohaiza Dashwood, Omer F. Yavuz, Sabeeta Kapoor, Trace A. Gustafson, Michelle I. Savage, Powel H. Brown, Shizuko Sei, Altaf Mohammed, Eduardo Vilar, Roderick H. Dashwood

Cancer Prev Res (Phila) (2021) 14 (3): 325–336.

DOI: https://doi.org/10.1158/1940-6207.CAPR-20-0262

Published: 02 March 2021

View article titled, Optimization of Erlotinib Plus Sulindac Dosing Regimens for Intestinal Cancer Prevention in an Apc-Mutant Model of Familial Adenomatous Polyposis (FAP)

Includes: Supplementary data

Journal Articles

Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D Supplementation in Premenopausal Women at High Risk for Breast Cancer (SWOG S0812)

Cancer Prev Res (Phila) (2019) 12 (7): 481–490.

DOI: https://doi.org/10.1158/1940-6207.CAPR-18-0444

Published: 03 July 2019

View article titled, Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D Supplementation in Premenopausal Women at High Risk for Breast Cancer (SWOG S0812)

Includes: Supplementary data

Journal Articles

A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease

Cancer Prev Res (Phila) (2018) 11 (4): 203–214.

DOI: https://doi.org/10.1158/1940-6207.CAPR-17-0354

Published: 01 April 2018

View article titled, A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease

Includes: Supplementary data

Journal Articles

Phase Ib Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Patients with Barrett's Esophagus

Cancer Prev Res (Phila) (2015) 8 (12): 1131–1137.

DOI: https://doi.org/10.1158/1940-6207.CAPR-14-0274-T

Published: 03 December 2015

View article titled, Phase Ib Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Patients with Barrett's Esophagus

Journal Articles

Abstract PR03: Targeting multiple cell cycle regulatory points for the prevention of triple-negative breast cancer

Beate Christiane Litzenburger, Ivan Peter Uray, Jamal Hill, Jun Zhang, Abhijit Mazumdar, Powel H. Brown

Cancer Prev Res (Phila) (2015) 8 (10_Supplement): PR03.

DOI: https://doi.org/10.1158/1940-6215.PREV-14-PR03

Published: 02 October 2015

View article titled, Abstract PR03: Targeting multiple cell cycle regulatory points for the prevention of triple-negative breast cancer

Journal Articles

Abstract PR-10: Randomized placebo controlled trial of pioglitazone for oral premalignant lesions: A cross-consortium collaborative study in progress

Jay O. Boyle, Frank G. Ondrey, Powel H. Brown, Howard H. Bailey, Kyung Mann Kim, Adel K. El-Naggar, Eva M. Szabo

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): PR-10.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-PR-10

Published: 24 October 2014

View article titled, Abstract PR-10: Randomized placebo controlled trial of pioglitazone for oral premalignant lesions: A cross-consortium collaborative study in progress

Journal Articles

Abstract A73: Randomized placebo-controlled trial of pioglitazone for oral premalignant lesions: A cross-consortium collaborative study in progress

Jay O. Boyle, Frank G. Ondrey, Powel H. Brown, Howard H. Bailey, KyungMann Kim, Adel K. El-Naggar, Eva M. Szabo

Cancer Prev Res (Phila) (2010) 3 (12_Supplement): A73.

DOI: https://doi.org/10.1158/1940-6207.PREV-10-A73

Published: 24 October 2014

View article titled, Abstract A73: Randomized placebo-controlled trial of pioglitazone for oral premalignant lesions: A cross-consortium collaborative study in progress

Journal Articles

Abstract A45: Targeting breast cancer stem cells using cancer preventive rexinoids

Jing Zhao, Yun Zhang, Jamal L. Hill, Abhijit Mazumdar, Powel H. Brown

Cancer Prev Res (Phila) (2011) 4 (10_Supplement): A45.

DOI: https://doi.org/10.1158/1940-6207.PREV-11-A45

Published: 23 October 2014

View article titled, Abstract A45: Targeting breast cancer stem cells using cancer preventive rexinoids

Journal Articles

Abstract A42: Autocrine-produced IL-6 and IL-8 are essential for the growth and maintenance of the transformed phenotype of basal-like breast cancer cells

Zachary C. Hartman, Anna Tsimelzon, Jamal Hill, Yun Zhang, Abhijit Mazumdar, Susan G. Hilsenbeck, Gordon Mills, Powel H. Brown

Cancer Prev Res (Phila) (2011) 4 (10_Supplement): A42.

DOI: https://doi.org/10.1158/1940-6207.PREV-11-A42

Published: 23 October 2014

View article titled, Abstract A42: Autocrine-produced IL-6 and IL-8 are essential for the growth and maintenance of the transformed phenotype of basal-like breast cancer cells

Journal Articles

Abstract B69: Cellular neutral lipid content is a novel biomarker of cancer preventive activity

Ivan P. Uray, Reid Bissonnette, Powel H. Brown

Cancer Prev Res (Phila) (2011) 4 (10_Supplement): B69.

DOI: https://doi.org/10.1158/1940-6207.PREV-11-B69

Published: 23 October 2014

View article titled, Abstract B69: Cellular neutral lipid content is a novel biomarker of cancer preventive activity

Journal Articles

Abstract A54: Combining the rexinoid bexarotene with tamoxifen to prevent ER‐negative mammary tumors in MMTV‐erbB2 mice

Abhijit Mazumdar, Yun Zhang, Powel H. Brown, Susan G. Hilsenbeck, Reid Bissonnette

Cancer Prev Res (Phila) (2010) 3 (1_Supplement): A54.

DOI: https://doi.org/10.1158/1940-6207.PREV-09-A54

Published: 21 October 2014

View article titled, Abstract A54: Combining the rexinoid bexarotene with tamoxifen to prevent ER‐negative mammary tumors in MMTV‐erbB2 mice

Journal Articles

Abstract A32: Identification of biomarkers in normal human breast cells regulated by the cancer preventive rexinoid LG100268

Jennifer M. Rodenberg, Ivan P. Uray, Hee‐Tae Kim, Julie Ann Mayer, Reid P. Bissonnette, Powel H. Brown

Cancer Prev Res (Phila) (2010) 3 (1_Supplement): A32.

DOI: https://doi.org/10.1158/1940-6207.PREV-09-A32

Published: 21 October 2014

View article titled, Abstract A32: Identification of biomarkers in normal human breast cells regulated by the cancer preventive rexinoid LG100268

NARROW

Phase II Trial of Nelipepimut-S Peptide Vaccine in Women with Ductal Carcinoma In Situ

Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer

Treatment Strategies and Mechanisms Associated with the Prevention of NASH-Associated HCC by a Toll-like Receptor 4 Inhibitor

Abstract IA017: Targeting the mTOR pathway for the prevention of triple-negative breast cancer

Abstract A012: Repurposing of the macrolide antibiotic clarithromycin for the prevention of lung cancer

Abstract IA013: Preclinical testing of CD73 inhibitors for pancreatic cancer immunoprevention

Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer

Lessons from the Failure to Complete a Trial of Denosumab in Women With a Pathogenic BRCA1/2 Variant Scheduling Risk-Reducing Salpingo-Oophorectomy

Optimization of Erlotinib Plus Sulindac Dosing Regimens for Intestinal Cancer Prevention in an Apc-Mutant Model of Familial Adenomatous Polyposis (FAP)

Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D Supplementation in Premenopausal Women at High Risk for Breast Cancer (SWOG S0812)

A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease

Phase Ib Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Patients with Barrett's Esophagus

Abstract PR03: Targeting multiple cell cycle regulatory points for the prevention of triple-negative breast cancer

Abstract PR-10: Randomized placebo controlled trial of pioglitazone for oral premalignant lesions: A cross-consortium collaborative study in progress

Abstract A73: Randomized placebo-controlled trial of pioglitazone for oral premalignant lesions: A cross-consortium collaborative study in progress

Abstract A45: Targeting breast cancer stem cells using cancer preventive rexinoids

Abstract A42: Autocrine-produced IL-6 and IL-8 are essential for the growth and maintenance of the transformed phenotype of basal-like breast cancer cells

Abstract B69: Cellular neutral lipid content is a novel biomarker of cancer preventive activity

Abstract A54: Combining the rexinoid bexarotene with tamoxifen to prevent ER‐negative mammary tumors in MMTV‐erbB2 mice

Abstract A32: Identification of biomarkers in normal human breast cells regulated by the cancer preventive rexinoid LG100268

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