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Michael B. Sporn
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Journal Articles

Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention

Di Zhang, Ana S. Leal, Sarah Carapellucci, Pritika H. Shahani, Jaskaran S. Bhogal, Samir Ibrahim, San Raban, Peter W. Jurutka, Pamela A. Marshall, Michael B. Sporn, Carl E. Wagner, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2019) 12 (4): 211–224.
https://doi.org/10.1158/1940-6207.CAPR-18-0317
Published: 01 April 2019
View articletitled, Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention
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Includes: Supplementary data
Journal Articles

Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762

Di Zhang, Ana S. Leal, Sarah Carapellucci, Kayla Zydeck, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2018) 11 (3): 143–156.
https://doi.org/10.1158/1940-6207.CAPR-17-0264
Published: 04 March 2018
View articletitled, Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762
Open the PDF for Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762 in another window
Includes: Supplementary data
Journal Articles

The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice

Martine Cao, Darlene B. Royce, Renee Risingsong, Charlotte R. Williams, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2016) 9 (1): 105–114.
https://doi.org/10.1158/1940-6207.CAPR-15-0325
Published: 06 January 2016
View articletitled, The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice
Open the PDF for The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice in another window
Includes: Supplementary data
Journal Articles

PARP Inhibitors for Chemoprevention—Reply

Ciric To, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (11): 1172.
https://doi.org/10.1158/1940-6207.CAPR-14-0264
Published: 02 November 2014
View articletitled, PARP Inhibitors for Chemoprevention—Reply
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Journal Articles

Abstract B76: Synthetic triterpenoids as candidate drugs for cancer prevention and treatment

Anna Rita Cantelmo, Ilaria Sogno, Rossella Calò, Elena Magnani, Giacomo Viggiani, Michael B. Sporn, Adriana Albini
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (10_Supplement): B76.
https://doi.org/10.1158/1940-6207.PREV-11-B76
Published: 23 October 2014
View articletitled, Abstract B76: Synthetic triterpenoids as candidate drugs for cancer prevention and treatment
Journal Articles

Abstract A103: The synthetic triterpenoid CDDO-methyl ester targets tumor-associated macrophages to delay carcinogenesis in the PyMT model of estrogen receptor negative breast cancer

Kim M. Tran, Renee Risingsong, Darlene Royce, Charlotte R. Williams, Michael B. Sporn, Karen Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (10_Supplement): A103.
https://doi.org/10.1158/1940-6207.PREV-11-A103
Published: 23 October 2014
View articletitled, Abstract A103: The synthetic triterpenoid CDDO-methyl ester targets tumor-associated macrophages to delay carcinogenesis in the PyMT model of estrogen receptor negative breast cancer
Journal Articles

Abstract PP01-01: Chemoprevention of Cancer: Past, Present, and Future

Michael B. Sporn
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2013) 6 (11_Supplement): PP01-01.
https://doi.org/10.1158/1940-6215.PREV-13-PP01-01
Published: 28 August 2014
View articletitled, Abstract PP01-01: Chemoprevention of Cancer: Past, Present, and Future
Journal Articles

The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient Mice

Ciric To, Eun-Hee Kim, Darlene B. Royce, Charlotte R. Williams, Ryan M. Collins, Renee Risingsong, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (7): 698–707.
https://doi.org/10.1158/1940-6207.CAPR-14-0047
Published: 01 July 2014
View articletitled, The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient Mice
Open the PDF for The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient Mice in another window
Journal Articles

Complete Protection against Aflatoxin B1-Induced Liver Cancer with a Triterpenoid: DNA Adduct Dosimetry, Molecular Signature, and Genotoxicity Threshold

Natalie M. Johnson, Patricia A. Egner, Victoria K. Baxter, Michael B. Sporn, Ryan S. Wible, Thomas R. Sutter, John D. Groopman, Thomas W. Kensler, Bill D. Roebuck
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (7): 658–665.
https://doi.org/10.1158/1940-6207.CAPR-13-0430
Published: 01 July 2014
View articletitled, Complete Protection against Aflatoxin B1-Induced Liver Cancer with a Triterpenoid: DNA Adduct Dosimetry, Molecular Signature, and Genotoxicity Threshold
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Journal Articles

Oral Administration of a Gemini Vitamin D Analog, a Synthetic Triterpenoid and the Combination Prevents Mammary Tumorigenesis Driven by ErbB2 Overexpression

Jae Young So, Joseph E. Wahler, Taesook Yoon, Amanda K. Smolarek, Yong Lin, Weichung Joe Shih, Hubert Maehr, Milan Uskokovic, Karen T. Liby, Michael B. Sporn, Nanjoo Suh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2013) 6 (9): 959–970.
https://doi.org/10.1158/1940-6207.CAPR-13-0087
Published: 03 September 2013
View articletitled, Oral Administration of a Gemini Vitamin D Analog, a Synthetic Triterpenoid and the Combination Prevents Mammary Tumorigenesis Driven by ErbB2 Overexpression
Open the PDF for Oral Administration of a Gemini Vitamin D Analog, a Synthetic Triterpenoid and the Combination Prevents Mammary Tumorigenesis Driven by ErbB2 Overexpression in another window
Journal Articles

Is Lycopene an Effective Agent for Preventing Prostate Cancer?

Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2013) 6 (5): 384–386.
https://doi.org/10.1158/1940-6207.CAPR-13-0026
Published: 01 May 2013
View articletitled, Is Lycopene an Effective Agent for Preventing Prostate Cancer?
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Journal Articles

The Synthetic Triterpenoid CDDO-Methyl Ester Delays Estrogen Receptor–Negative Mammary Carcinogenesis in Polyoma Middle T Mice

Kim Tran, Renee Risingsong, Darlene Royce, Charlotte R. Williams, Michael B. Sporn, Karen Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2012) 5 (5): 726–734.
https://doi.org/10.1158/1940-6207.CAPR-11-0404
Published: 03 May 2012
View articletitled, The Synthetic Triterpenoid CDDO-Methyl Ester Delays Estrogen Receptor–Negative Mammary Carcinogenesis in Polyoma Middle T Mice
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Includes: Supplementary data
Journal Articles

CDDO-Methyl Ester Delays Breast Cancer Development in Brca1-Mutated Mice

Eun-Hee Kim, Chuxia Deng, Michael B. Sporn, Darlene B. Royce, Renee Risingsong, Charlotte R. Williams, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2012) 5 (1): 89–97.
https://doi.org/10.1158/1940-6207.CAPR-11-0359
Published: 03 January 2012
View articletitled, CDDO-Methyl Ester Delays Breast Cancer Development in Brca1-Mutated Mice
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Journal Articles

CDDO-Imidazolide Induces DNA Damage, G2/M Arrest and Apoptosis in BRCA1-Mutated Breast Cancer Cells

Eun-Hee Kim, Chu-Xia Deng, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (3): 425–434.
https://doi.org/10.1158/1940-6207.CAPR-10-0153
Published: 02 March 2011
View articletitled, CDDO-Imidazolide Induces DNA Damage, G2/M Arrest and Apoptosis in BRCA1-Mutated Breast Cancer Cells
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Journal Articles

Synthetic Triterpenoids Prolong Survival in a Transgenic Mouse Model of Pancreatic Cancer

Karen T. Liby, Darlene B. Royce, Renee Risingsong, Charlotte R. Williams, Anirban Maitra, Ralph H. Hruban, Michael B. Sporn
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (11): 1427–1434.
https://doi.org/10.1158/1940-6207.CAPR-10-0197
Published: 08 November 2010
View articletitled, Synthetic Triterpenoids Prolong Survival in a Transgenic Mouse Model of Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Triterpenoids CDDO-Methyl Ester or CDDO-Ethyl Amide and Rexinoids LG100268 or NRX194204 for Prevention and Treatment of Lung Cancer in Mice

Karen Liby, Renee Risingsong, Darlene B. Royce, Charlotte R. Williams, Tian Ma, Mark M. Yore, Michael B. Sporn
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2009) 2 (12): 1050–1058.
https://doi.org/10.1158/1940-6207.CAPR-09-0085
Published: 03 December 2009
View articletitled, Triterpenoids CDDO-Methyl Ester or CDDO-Ethyl Amide and Rexinoids LG100268 or NRX194204 for Prevention and Treatment of Lung Cancer in Mice
Open the PDF for Triterpenoids CDDO-Methyl Ester or CDDO-Ethyl Amide and Rexinoids LG100268 or NRX194204 for Prevention and Treatment of Lung Cancer in Mice in another window
Journal Articles

Clinical Prevention of Recurrence of Colorectal Adenomas by the Combination of Difluoromethylornithine and Sulindac: An Important Milestone

Michael B. Sporn, Waun Ki Hong
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2008) 1 (1): 9–11.
https://doi.org/10.1158/1940-6207.CAPR-08-0049
Published: 09 June 2008
View articletitled, Clinical Prevention of Recurrence of Colorectal Adenomas by the Combination of Difluoromethylornithine and Sulindac: An Important Milestone
Open the PDF for Clinical Prevention of Recurrence of Colorectal Adenomas by the Combination of Difluoromethylornithine and Sulindac: An Important Milestone in another window
Includes: Supplementary data