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Karen T. Liby
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Journal Articles

Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention

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Di Zhang, Ana S. Leal, Sarah Carapellucci, Pritika H. Shahani, Jaskaran S. Bhogal, Samir Ibrahim, San Raban, Peter W. Jurutka, Pamela A. Marshall, Michael B. Sporn, Carl E. Wagner, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2019) 12 (4): 211–224.
https://doi.org/10.1158/1940-6207.CAPR-18-0317
Published: 01 April 2019
View articletitled, Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention
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Includes: Supplementary data
Journal Articles

A BET Bromodomain Inhibitor Suppresses Adiposity-Associated Malignant Transformation

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Debrup Chakraborty, Vanessa Benham, Vladislav Jdanov, Blair Bullard, Ana S. Leal, Karen T. Liby, Jamie J. Bernard
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2018) 11 (3): 129–142.
https://doi.org/10.1158/1940-6207.CAPR-17-0262
Published: 04 March 2018
View articletitled, A BET Bromodomain Inhibitor Suppresses Adiposity-Associated Malignant Transformation
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Includes: Supplementary data
Journal Articles

Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762

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Di Zhang, Ana S. Leal, Sarah Carapellucci, Kayla Zydeck, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2018) 11 (3): 143–156.
https://doi.org/10.1158/1940-6207.CAPR-17-0264
Published: 04 March 2018
View articletitled, Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762
Open the PDF for Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762 in another window
Includes: Supplementary data
Journal Articles

The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice

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Martine Cao, Darlene B. Royce, Renee Risingsong, Charlotte R. Williams, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2016) 9 (1): 105–114.
https://doi.org/10.1158/1940-6207.CAPR-15-0325
Published: 06 January 2016
View articletitled, The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice
Open the PDF for The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice in another window
Includes: Supplementary data
Journal Articles

PARP Inhibitors for Chemoprevention—Reply

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Ciric To, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (11): 1172.
https://doi.org/10.1158/1940-6207.CAPR-14-0264
Published: 02 November 2014
View articletitled, PARP Inhibitors for Chemoprevention—Reply
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Journal Articles

Abstract CN04-01: New drugs for the chemoprevention of experimental breast cancer

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Karen T. Liby, Kim Tran, Eun-Hee Kim
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (10_Supplement): CN04-01.
https://doi.org/10.1158/1940-6207.PREV-11-CN04-01
Published: 23 October 2014
View articletitled, Abstract CN04-01: New drugs for the chemoprevention of experimental breast cancer
Journal Articles

The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient Mice

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Ciric To, Eun-Hee Kim, Darlene B. Royce, Charlotte R. Williams, Ryan M. Collins, Renee Risingsong, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (7): 698–707.
https://doi.org/10.1158/1940-6207.CAPR-14-0047
Published: 01 July 2014
View articletitled, The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient Mice
Open the PDF for The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient Mice in another window
Journal Articles

Abstract ED02-04: Using mouse models to develop new drugs and strategies for prevention

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Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2012) 5 (11_Supplement): ED02-04.
https://doi.org/10.1158/1940-6207.PREV-12-ED02-04
Published: 23 January 2014
View articletitled, Abstract ED02-04: Using mouse models to develop new drugs and strategies for prevention
Journal Articles

Oral Administration of a Gemini Vitamin D Analog, a Synthetic Triterpenoid and the Combination Prevents Mammary Tumorigenesis Driven by ErbB2 Overexpression

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Jae Young So, Joseph E. Wahler, Taesook Yoon, Amanda K. Smolarek, Yong Lin, Weichung Joe Shih, Hubert Maehr, Milan Uskokovic, Karen T. Liby, Michael B. Sporn, Nanjoo Suh
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2013) 6 (9): 959–970.
https://doi.org/10.1158/1940-6207.CAPR-13-0087
Published: 03 September 2013
View articletitled, Oral Administration of a Gemini Vitamin D Analog, a Synthetic Triterpenoid and the Combination Prevents Mammary Tumorigenesis Driven by ErbB2 Overexpression
Open the PDF for Oral Administration of a Gemini Vitamin D Analog, a Synthetic Triterpenoid and the Combination Prevents Mammary Tumorigenesis Driven by ErbB2 Overexpression in another window
Journal Articles

Is Lycopene an Effective Agent for Preventing Prostate Cancer?

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Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2013) 6 (5): 384–386.
https://doi.org/10.1158/1940-6207.CAPR-13-0026
Published: 01 May 2013
View articletitled, Is Lycopene an Effective Agent for Preventing Prostate Cancer?
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Journal Articles

CDDO-Methyl Ester Delays Breast Cancer Development in Brca1-Mutated Mice

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Eun-Hee Kim, Chuxia Deng, Michael B. Sporn, Darlene B. Royce, Renee Risingsong, Charlotte R. Williams, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2012) 5 (1): 89–97.
https://doi.org/10.1158/1940-6207.CAPR-11-0359
Published: 03 January 2012
View articletitled, CDDO-Methyl Ester Delays Breast Cancer Development in Brca1-Mutated Mice
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Journal Articles

CDDO-Imidazolide Induces DNA Damage, G2/M Arrest and Apoptosis in BRCA1-Mutated Breast Cancer Cells

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Eun-Hee Kim, Chu-Xia Deng, Michael B. Sporn, Karen T. Liby
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (3): 425–434.
https://doi.org/10.1158/1940-6207.CAPR-10-0153
Published: 02 March 2011
View articletitled, CDDO-Imidazolide Induces DNA Damage, G2/M Arrest and Apoptosis in BRCA1-Mutated Breast Cancer Cells
Open the PDF for CDDO-Imidazolide Induces DNA Damage, G2/M Arrest and Apoptosis in BRCA1-Mutated Breast Cancer Cells in another window
Journal Articles

Synthetic Triterpenoids Prolong Survival in a Transgenic Mouse Model of Pancreatic Cancer

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Karen T. Liby, Darlene B. Royce, Renee Risingsong, Charlotte R. Williams, Anirban Maitra, Ralph H. Hruban, Michael B. Sporn
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (11): 1427–1434.
https://doi.org/10.1158/1940-6207.CAPR-10-0197
Published: 08 November 2010
View articletitled, Synthetic Triterpenoids Prolong Survival in a Transgenic Mouse Model of Pancreatic Cancer
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Includes: Supplementary data