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Christine E. McLaren
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Journal Articles

A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction among Individuals with History of Colorectal Adenomas and Elevated Body Mass Index

Jason A. Zell, Christine E. McLaren, Timothy R. Morgan, Michael J. Lawson, Sherif Rezk, C. Gregory Albers, Wen-Pin Chen, Joseph C. Carmichael, Jinah Chung, Ellen Richmond, L.M. Rodriguez, Eva Szabo, Leslie G. Ford, Michael N. Pollak, Frank L. Meyskens
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2020) 13 (2): 203–212.
https://doi.org/10.1158/1940-6207.CAPR-18-0262
Published: 05 February 2020
View article titled, A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction among Individuals with History of Colorectal Adenomas and Elevated Body Mass Index
Open the PDF for A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction among Individuals with History of Colorectal Adenomas and Elevated Body Mass Index in another window
Includes: Supplementary data
Journal Articles

Abstract A21: A Phase IIa trial of metformin for colorectal cancer risk reduction among patients with a history of colorectal adenomas and elevated body mass index

Jason A. Zell, Christine E. McLaren, Timothy R. Morgan, Michael J. Lawson, Sherif Rezk, Gregory C. Albers, Wen-Pin Chen, Joseph C. Carmichael, Luz Rodriguez, Eva Szabo, Leslie Ford, Michael Pollak, Frank L. Meyskens
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2015) 8 (10_Supplement): A21.
https://doi.org/10.1158/1940-6215.PREV-14-A21
Published: 02 October 2015
View article titled, Abstract A21: A Phase IIa trial of metformin for colorectal cancer risk reduction among patients with a history of colorectal adenomas and elevated body mass index
Journal Articles

Abstract PR-01: Properties of adenomas in subjects treated with difluoromethylornithine and sulindac for reduction of colorectal adenomas

Philip M. Carpenter, Wen-Pin Chen, Christine E. McLaren, Eugene W. Gerner, Frank L. Meyskens, Jr.
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2011) 4 (10_Supplement): PR-01.
https://doi.org/10.1158/1940-6207.PREV-11-PR-01
Published: 23 October 2014
View article titled, Abstract PR-01: Properties of adenomas in subjects treated with difluoromethylornithine and sulindac for reduction of colorectal adenomas
Journal Articles

Abstract A29: Rectal mucosal polyamine and PGE2 levels and risk of colorectal adenomas in a phase IIb/III trial of combination difluoromethylornithine (DFMO) plus sulindac

Patricia A. Thompson, Betsy C. Wertheim, Jason A. Zell, Bonnie LeFleur, Wen‐Pin Chen, Christine E. McLaren, Frank L. Meyskens, Eugene W. Gerner
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2010) 3 (1_Supplement): A29.
https://doi.org/10.1158/1940-6207.PREV-09-A29
Published: 21 October 2014
View article titled, Abstract A29: Rectal mucosal polyamine and PGE<sub>2</sub> levels and risk of colorectal adenomas in a phase IIb/III trial of combination difluoromethylornithine (DFMO) plus sulindac
Journal Articles

A Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial of Lovastatin for Various Endpoints of Melanoma Pathobiology

Kenneth G. Linden, Sancy A. Leachman, Jonathan S. Zager, James G. Jakowatz, Jaye L. Viner, Christine E. McLaren, Ronald J. Barr, Philip M. Carpenter, Wen-Pin Chen, Craig A. Elmets, Joseph A. Tangrea, Sung-Jig Lim, Alistair J. Cochran, Frank L. Meyskens, Jr
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2014) 7 (5): 496–504.
https://doi.org/10.1158/1940-6207.CAPR-13-0189
Published: 01 May 2014
View article titled, A Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial of Lovastatin for Various Endpoints of Melanoma Pathobiology
Open the PDF for A Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial of Lovastatin for Various Endpoints of Melanoma Pathobiology in another window
Includes: Supplementary data
Journal Articles

Risk of Cardiovascular Events in a Randomized Placebo-Controlled, Double-Blind Trial of Difluoromethylornithine plus Sulindac for the Prevention of Sporadic Colorectal Adenomas

Jason A. Zell, Daniel Pelot, Wen-Pin Chen, Christine E. McLaren, Eugene W. Gerner, Frank L. Meyskens
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2009) 2 (3): 209–212.
https://doi.org/10.1158/1940-6207.CAPR-08-0203
Published: 05 March 2009
View article titled, Risk of Cardiovascular Events in a Randomized Placebo-Controlled, Double-Blind Trial of Difluoromethylornithine plus Sulindac for the Prevention of Sporadic Colorectal Adenomas
Open the PDF for Risk of Cardiovascular Events in a Randomized Placebo-Controlled, Double-Blind Trial of Difluoromethylornithine plus Sulindac for the Prevention of Sporadic Colorectal Adenomas in another window
Includes: Supplementary data
Journal Articles

Longitudinal Assessment of Air Conduction Audiograms in a Phase III Clinical Trial of Difluoromethylornithine and Sulindac for Prevention of Sporadic Colorectal Adenomas

Christine E. McLaren, Sharon Fujikawa-Brooks, Wen-Pin Chen, Daniel L. Gillen, Daniel Pelot, Eugene W. Gerner, Frank L. Meyskens, Jr.
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2008) 1 (7): 514–521.
https://doi.org/10.1158/1940-6207.CAPR-08-0074
Published: 08 December 2008
View article titled, Longitudinal Assessment of Air Conduction Audiograms in a Phase III Clinical Trial of Difluoromethylornithine and Sulindac for Prevention of Sporadic Colorectal Adenomas
Open the PDF for Longitudinal Assessment of Air Conduction Audiograms in a Phase III Clinical Trial of Difluoromethylornithine and Sulindac for Prevention of Sporadic Colorectal Adenomas in another window
Includes: Supplementary data
Journal Articles

Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind Trial

Frank L. Meyskens, Jr., Christine E. McLaren, Daniel Pelot, Sharon Fujikawa-Brooks, Philip M. Carpenter, Ernest Hawk, Gary Kelloff, Michael J. Lawson, Jayashri Kidao, John McCracken, C. Gregory Albers, Dennis J. Ahnen, D. Kim Turgeon, Steven Goldschmid, Peter Lance, Curt H. Hagedorn, Daniel L. Gillen, Eugene W. Gerner
Journal: Cancer Prevention Research
Cancer Prev Res (Phila) (2008) 1 (1): 32–38.
https://doi.org/10.1158/1940-6207.CAPR-08-0042
Published: 09 June 2008
View article titled, Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind Trial
Open the PDF for Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind Trial in another window
Includes: Supplementary data