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1 May 2016
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Cover Image
Cover Image
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The cover image shows H&E staining of a sarcomatoid malignant mesothelioma that formed in the peritoneum of an asbestos-exposed Asc+/- mouse. Asc-deficient mice have an impaired immune response to asbestos fibers due to the presence of a defective NALP3/NLRP3 inflammasome, which prevents the release of mature IL1b. For more information, see the article (beginning on p. 406) by Kadariya and colleagues.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1940-6207
EISSN 1940-6215
Issue Sections
Commentary
Research Articles
Author Choice
Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Emily L. Rossi; Rebecca E. de Angel; Laura W. Bowers; Subreen A. Khatib; Laura A. Smith; Eric Van Buren; Priya Bhardwaj; Dilip Giri; Marcos R. Estecio; Melissa A. Troester; Brionna Y. Hair; Erin L. Kirk; Ting Gong; Jianjun Shen; Andrew J. Dannenberg; Stephen D. Hursting
A Randomized, Placebo-Controlled, Phase II, Presurgical Biomarker Trial of Celecoxib Versus Exemestane in Postmenopausal Breast Cancer Patients
Valentina Aristarco; Davide Serrano; Sara Gandini; Harriet Johansson; Debora Macis; Aliana Guerrieri-Gonzaga; Matteo Lazzeroni; Irene Feroce; Giancarlo Pruneri; Gianmatteo Pagani; Antonio Toesca; Pietro Caldarella; Andrea DeCensi; Bernardo Bonanni
Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques
Fitriya N. Dewi; Charles E. Wood; Cynthia J. Willson; Thomas C. Register; Cynthia J. Lees; Timothy D. Howard; Zhiqing Huang; Susan K. Murphy; Janet A. Tooze; Jeff W. Chou; Lance D. Miller; J. Mark Cline
Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers
Jian-Min Yuan; Irina Stepanov; Sharon E. Murphy; Renwei Wang; Sharon Allen; Joni Jensen; Lori Strayer; Jennifer Adams-Haduch; Pramod Upadhyaya; Chap Le; Mindy S. Kurzer; Heather H. Nelson; Mimi C. Yu; Dorothy Hatsukami; Stephen S. Hecht
Inflammation-Related IL1β/IL1R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma
Yuwaraj Kadariya; Craig W. Menges; Jacqueline Talarchek; Kathy Q. Cai; Andres J. Klein-Szanto; Ralph A. Pietrofesa; Melpo Christofidou-Solomidou; Mitchell Cheung; Brooke T. Mossman; Arti Shukla; Joseph R. Testa
Letters to the Editor
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