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1 August 2015
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Cover Image
Cover Image
China has made major strides in studying the epidemiology and etiology of the traditionally prevalent cancers since 1970s. As illustrated on the cover image, there are noted high-incidence areas of major cancers such as those of stomach, liver, esophagus, lung, cervix and nasopharynx in China. Research in these areas have made important contributions to the prevention of these cancers, and the age-standardized incidence rates of most of these cancers have decreased. However, with the dramatic lifestyle and environmental changes in the past 30 years associated with rapid economic development, China is facing a serious challenge from both the still-prevalent traditional cancers and new emerging cancers, especially those of the lung, colon and breast. In 2012, there were 3.07 million new cancer cases and 2.21 million cancer deaths in China, and the numbers are expected to increase to 5 and 3.86 million, respectively, by 2030. Much more research and practical measures are needed for the prevention of cancer. For more information about the past achievements and present needs in cancer prevention research in China, see the article by S. Yu and C.S. Yang et al. (beginning on page 662). - PDF Icon PDF LinkTable of Contents
ISSN 1940-6207
EISSN 1940-6215
Issue Sections
Commentary
Review
Research Articles
Activation of the Mitochondrial Apoptotic Pathway Produces Reactive Oxygen Species and Oxidative Damage in Hepatocytes That Contribute to Liver Tumorigenesis
Hayato Hikita; Takahiro Kodama; Satoshi Tanaka; Yoshinobu Saito; Yasutoshi Nozaki; Tasuku Nakabori; Satoshi Shimizu; Yoshito Hayashi; Wei Li; Minoru Shigekawa; Ryotaro Sakamori; Takuya Miyagi; Naoki Hiramatsu; Tomohide Tatsumi; Tetsuo Takehara
Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer
Norihisa Ichimura; Keiko Shinjo; Byonggu An; Yasuhiro Shimizu; Kenji Yamao; Fumiharu Ohka; Keisuke Katsushima; Akira Hatanaka; Masayuki Tojo; Eiichiro Yamamoto; Hiromu Suzuki; Minoru Ueda; Yutaka Kondo
Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin
Yira Bermudez; Steven P. Stratton; Clara Curiel-Lewandrowski; James Warneke; Chengcheng Hu; George T. Bowden; Sally E. Dickinson; Zigang Dong; Ann M. Bode; Kathylynn Saboda; Christine A. Brooks; Emanuel F. Petricoin, III; Craig A. Hurst; David S. Alberts; Janine G. Einspahr
Prediagnostic Obesity and Physical Inactivity Are Associated with Shorter Telomere Length in Prostate Stromal Cells
Corinne E. Joshu; Sarah B. Peskoe; Christopher M. Heaphy; Stacey A. Kenfield; Erin L. Van Blarigan; Lorelei A. Mucci; Edward L. Giovannucci; Meir J. Stampfer; GhilSuk Yoon; Thomas K. Lee; Jessica L. Hicks; Angelo M. De Marzo; Alan K. Meeker; Elizabeth A. Platz
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