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1 August 2011
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Cover Image
Cover Image
The cover image is a photomicrograph (40X magnification; courtesy of Yun Zhang, Jamal Hill, Abhijit Mazumdar, and Petra Den Hollander) of mammary duct epithelial cells in the mammary gland of an MMTV-erbB2 mouse (FVB/N-Tg(MMTVneu)202Mul/J). The cells were stained for HER2 (c-erbB2) expression [using the Ab-1 (21N) c-erbB2/HER-2 antibody]. Normal mammary duct epithelial cells (predominantly to the right) are seen along with a region of hyperplasia (predominantly to the left) within the normal stromal tissue. Expression of the HER2 (c-erbB2) transgene in cells shows up as membranous brown staining. HER family targeting is in current testing for breast cancer chemoprevention. See articles by Howe and Brown (beginning on page 1149), DeCensi et al.(beginning on page 1181), and Li et al.(beginning on page 1190) for more information. - PDF Icon PDF LinkTable of Contents
ISSN 1940-6207
EISSN 1940-6215
Issue Sections
Perspective
Minireview
Review
Research Articles
Lapatinib Activity in Premalignant Lesions and HER-2–Positive Cancer of the Breast in a Randomized, Placebo-Controlled Presurgical Trial
Andrea DeCensi; Matteo Puntoni; Giancarlo Pruneri; Aliana Guerrieri-Gonzaga; Matteo Lazzeroni; Davide Serrano; Debora Macis; Harriet Johansson; Oriana Pala; Alberto Luini; Paolo Veronesi; Viviana Galimberti; Maria Cristina Dotti; Giuseppe Viale; Bernardo Bonanni
Effects of Human Oral Mucosal Tissue, Saliva, and Oral Microflora on Intraoral Metabolism and Bioactivation of Black Raspberry Anthocyanins
Susan R. Mallery; Deric E. Budendorf; Matthew P. Larsen; Ping Pei; Meng Tong; Andrew S. Holpuch; Peter E. Larsen; Gary D. Stoner; Henry W. Fields; Kenneth K. Chan; Yonghua Ling; Zhongfa Liu
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