Issues

Anti-estrogen chemoprevention for breast cancer can reduce the risk of developing breast cancer by up to 65% among high-risk women, but has low uptake, particularly among racial/ethnic minority women. There is therefore a clear need to identify strategies to improve uptake of breast cancer chemoprevention among diverse populations of women. In the study starting on page 399, McGuinness and colleagues describe five strategies that they utilized to identify and recruit women at high risk for breast cancer to a randomized trial evaluating web-based decision support tools designed to enhance shared decision-making between patient and providers regarding breast cancer prevention strategies. Through these varied strategies, ranging from automated breast cancer risk calculation using electronic health record data to clinical encounters with enrolled healthcare providers, the authors were able to recruit a diverse population of women, including over 40% non-Whites. The recruitment strategies they describe could be useful for future breast cancer chemoprevention trials to allow for more efficient identification of high-risk women and also improve representation of racial/ethnic minorities. The cover depicts multi-ethnic women.