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1 February 2021
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Cover Image
In Brazil, colorectal cancer is the second most common cancer among men and women and exhibits high mortality rates, partially due to late-stage presentation. To date, Brazil has not implemented a nationally organized colorectal screening program. Barretos Cancer Hospital is one of the largest cancer hospitals in Brazil, which cares for underserved healthcare patients from all over the country. Barretos Cancer Hospital developed a FIT-based organized colorectal screening program as part of the efforts to improve CRC outcomes. In the study starting on page 241, Guimarães and colleagues demonstrated that this colorectal cancer screening program achieved desirable quality metrics aligned with the EU Guidelines’ recommendations. Further, a shift towards earlier stages seen in screening-detected CRCs suggests an exciting opportunity to improve CRC outcomes. The cover image shows the distribution of screening participants across the Brazilian geographical regions, where the darkest green corresponds to the highest number of participants. The red dot is Barretos Cancer Hospital’s location, in Barretos’s city at the State of São Paulo. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 1940-6207
EISSN 1940-6215
Issue Sections
Commentary
Review
Research Articles
Impact of Personalized Genetic Breast Cancer Risk Estimation With Polygenic Risk Scores on Preventive Endocrine Therapy Intention and Uptake
Julian O. Kim; Daniel J. Schaid; Celine M. Vachon; Andrew Cooke; Fergus J. Couch; Christina A. Kim; Jason P. Sinnwell; Linda Hasadsri; Daniela L. Stan; Benjamin Goldenberg; Lonzetta Neal; Debjani Grenier; Amy C. Degnim; Lori A. Thicke; Sandhya Pruthi
BRIP1, a Gene Potentially Implicated in Familial Colorectal Cancer Type X
Lorena Martín-Morales; Pilar Garre; Víctor Lorca; Marta Cazorla; Patricia Llovet; Inmaculada Bando; Vanesa García-Barberan; María Luisa González-Morales; Clara Esteban-Jurado; Miguel de la Hoya; Sergi Castellví-Bel; Trinidad Caldés
Author Choice
Assessment of and Interventions for Women at High Risk for Breast or Ovarian Cancer: A Survey of Primary Care Physicians
Goli Samimi; Brandy M. Heckman-Stoddard; Christine Holmberg; Bethany Tennant; Bonny Bloodgood Sheppard; Kisha I. Coa; Shelley S. Kay; Leslie G. Ford; Eva Szabo; Lori M. Minasian
Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant
Suzanne P. MacFarland; Jessica E. Ebrahimzadeh; Kristin Zelley; Lubna Begum; Lee M. Bass; Randall E. Brand; Beth Dudley; Douglas S. Fishman; Amanda Ganzak; Eve Karloski; Alicia Latham; Xavier Llor; Sharon Plon; Mary K. Riordan; Sarah R. Scollon; Zsofia K. Stadler; Sapna Syngal; Chinedu Ukaegbu; Jennifer M. Weiss; Matthew B. Yurgelun; Garrett M. Brodeur; Petar Mamula; Bryson W. Katona
THBS2/CA19-9 Detecting Pancreatic Ductal Adenocarcinoma at Diagnosis Underperforms in Prediagnostic Detection: Implications for Biomarker Advancement
Shirsa Udgata; Naomi Takenaka; William R. Bamlet; Ann L. Oberg; Stephanie S. Yee; Erica L. Carpenter; Daniel Herman; Jungsun Kim; Gloria M. Petersen; Kenneth S. Zaret
DNA Methylation in Peripheral Blood and Risk of Gastric Cancer: A Prospective Nested Case–control Study
James A Chamberlain; Pierre-Antoine Dugué; Julie K. Bassett; Roger L. Milne; Jihoon E. Joo; Ee Ming Wong; Maree T. Brinkman; Geoffrey W. Stuart; Alex Boussioutas; Melissa C. Southey; Graham G. Giles; Hazel Mitchell; Dallas R. English; Allison M. Hodge
The Performance of Colorectal Cancer Screening in Brazil: The First Two Years of the Implementation Program in Barretos Cancer Hospital
Denise Peixoto Guimarães; Larissa Andreoli Mantuan; Marco Antonio de Oliveira; Raphael Luiz Junior; Allini Mafra da Costa; Silvana Rossi; Gilberto Fava; Leonardo Nogueira Taveira; Kelly Menezio Giardina; Thais Talarico; Maraisa Costa; Cristovam Scapulatempo-Neto; Marcus Medeiros Matsushita; Carlos Augusto Véo; Jose Humberto Tavares Fregnani; Rui Manuel Reis; Ernest T. Hawk; Edmundo Carvalho Mauad
Proof of Concept of a Personalized Genetic Risk Tool to Promote Smoking Cessation: High Acceptability and Reduced Cigarette Smoking
Alex T. Ramsey; Jessica L. Bourdon; Michael Bray; Amelia Dorsey; Maia Zalik; Amanda Pietka; Patricia Salyer; Li-Shiun Chen; Timothy B. Baker; Marcus R. Munafò; Laura J. Bierut
Author Choice
PROgesterone Therapy for Endometrial Cancer Prevention in Obese Women (PROTEC) Trial: A Feasibility Study
Abigail E. Derbyshire; Jennifer L. Allen; Matthew Gittins; Bhavna Lakhiani; James Bolton; Joseph Shaw; Philip W. Pemberton; Michelle Needham; Michelle L. MacKintosh; Richard J. Edmondson; Henry C. Kitchener; Emma J. Crosbie
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