Tobacco use — smoked or smokeless — is now recognized as having serious adverse effects on cancer treatment, outcome and quality of life, in addition to its causal role in cancer etiology. Further, nicotine itself has been shown to interfere with the anti-apoptotic effects of some chemotherapeutic agents. Two major thrusts are imperative for research and clinical efforts:

  1. To further document the adverse effects of tobacco use through systematic efforts in all clinical trials, by incorporating assessments at every patient visit; and

  2. To incorporate tobacco cessation treatment as a routine, mandatory aspect of patient care.

Efforts to achieve these goals will be described, as well as an overview of current tobacco cessation programs targeted to oncology patients.

Citation Information: Cancer Prev Res 2011;4(10 Suppl):PL03-01.