As the risk for recurrence following breast cancer remains elevated for the majority of women for at least 15–20 years, there is considerable interest in whether the way someone lives their life can improve prognosis. There are now numerous cohort studies that have post diagnoses measures of dietary and physical activity patterns as well as body weight and have reported on associations with recurrence. Two large randomized dietary trials have also reported both primary and secondary analyses. However, there is a degree of inconsistency in the published findings.

This presentation will discuss the evidence for a role of dietary patterns, physical activity and body weight in recurrence. Dietary patterns will include those that are plant based and those with a high animal fat intake, as well as considering the impact of nutritional supplements. It will compare physical activity patterns that include half or multiple times the recommended daily pattern. With respect to obesity, the question is whether the overweight are at increased risk as well as those who are obese, and whether there are any obese women who are not at increased risk. Finally, the presentation will consider whether the real issue is not a particular lifestyle pattern but a cluster of behavioral patterns that are linked to increased risk of recurrence.

Citation Information: Cancer Prev Res 2011;4(10 Suppl):ED02-03.