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Vikram R. Juneja
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Journal Articles

Abstract PR009: Generation of T cell responses against broad KRAS hotspot neoantigens using a single large-scale process as the basis for an adoptive cell therapy or for TCR discovery

Brandon P Conn, Jared L Dietze, Christian J Yee, Margaret M Hallisey, Irais Ortiz-Caraveo, Marit M van Buuren, Richard B Gaynor, Kendra C Foley, Jaewon Choi, Vikram R Juneja
Journal: Cancer Immunology Research
Cancer Immunol Res (2025) 13 (2_Supplement): PR009.
https://doi.org/10.1158/2326-6074.IO2025-PR009
Published: 23 February 2025
View articletitled, Abstract PR009: Generation of T cell responses against broad KRAS hotspot neoantigens using a single large-scale process as the basis for an adoptive cell therapy or for TCR discovery
Journal Articles

Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses

Xia Bu, Vikram R. Juneja, Carol G. Reynolds, Kathleen M. Mahoney, Melissa T. Bu, Kathleen A. McGuire, Seth Maleri, Ping Hua, Baogong Zhu, Sarah R. Klein, Edward A. Greenfield, Philippe Armand, Jerome Ritz, Arlene H. Sharpe, Gordon J. Freeman
Journal: Cancer Immunology Research
Cancer Immunol Res (2021) 9 (12): 1465–1475.
https://doi.org/10.1158/2326-6066.CIR-21-0493
Published: 01 December 2021
View articletitled, Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses
Open the PDF for Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses in another window
Journal Articles

Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells

Jefte M. Drijvers, Jacob E. Gillis, Tara Muijlwijk, Thao H. Nguyen, Emily F. Gaudiano, Isaac S. Harris, Martin W. LaFleur, Alison E. Ringel, Cong-Hui Yao, Kiran Kurmi, Vikram R. Juneja, Justin D. Trombley, Marcia C. Haigis, Arlene H. Sharpe
Journal: Cancer Immunology Research
Cancer Immunol Res (2021) 9 (2): 184–199.
https://doi.org/10.1158/2326-6066.CIR-20-0384
Published: 03 February 2021
View articletitled, Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells
Open the PDF for Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells in another window
Includes: Supplementary data
Journal Articles

Abstract PR9: Loss of PD-1 promotes antitumor immunity by improving functions of both PD-1+ and PD-1- CD8+ T cells in the tumor microenvironment

Kristen E. Pauken, Vikram R. Juneja, Alison Ringel, Jared H. Rowe, Kelly P. Burke, Peter T. Sage, Martin W. LaFleur, Juhi R. Kuchroo, Noga Ron-Harel, Seth Maleri, Jaclyn M. Long, Gordon J. Freeman, Nicolas Chevrier, Marcia C. Haigis, Arlene H. Sharpe
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (3_Supplement): PR9.
https://doi.org/10.1158/2326-6074.TUMIMM19-PR9
Published: 02 March 2020
View articletitled, Abstract PR9: Loss of PD-1 promotes antitumor immunity by improving functions of both PD-1+ and PD-1- CD8+ T cells in the tumor microenvironment
Journal Articles

Abstract A19: PD-1 modulation promotes antitumor immunity by improving metabolic fitness of both PD-1+ and PD-1- CD8+ T cells in the tumor

Kristen E. Pauken, Vikram R. Juneja, Peter T. Sage, Martin W. LaFleur, Juhi R. Kuchroo, Alison Ringel, Noga Ron-Harel, Seth P. Maleri, Gordon J. Freeman, Nicolas Chevrier, Marcia C. Haigis, Arlene H. Sharpe
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (9_Supplement): A19.
https://doi.org/10.1158/2326-6074.TUMIMM17-A19
Published: 01 September 2018
View articletitled, Abstract A19: PD-1 modulation promotes antitumor immunity by improving metabolic fitness of both PD-1+ and PD-1- CD8+ T cells in the tumor
Journal Articles

Abstract A097: Tumor PDL1 blocks CTL cytotoxicity

Kathleen A. McGuire, Vikram R. Juneja, Robert T. Manguso, Martin W. LaFleur, Natalie Collins, W. Nicholas Haining, Gordon J. Freeman, Arlene H. Sharpe
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): A097.
https://doi.org/10.1158/2326-6066.IMM2016-A097
Published: 31 October 2016
View articletitled, Abstract A097: Tumor PDL1 blocks CTL cytotoxicity
Journal Articles

Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade

Zachary A. Cooper, Vikram R. Juneja, Peter T. Sage, Dennie T. Frederick, Adriano Piris, Devarati Mitra, Jennifer A. Lo, F. Stephen Hodi, Gordon J. Freeman, Marcus W. Bosenberg, Martin McMahon, Keith T. Flaherty, David E. Fisher, Arlene H. Sharpe, Jennifer A. Wargo
Journal: Cancer Immunology Research
Cancer Immunol Res (2014) 2 (7): 643–654.
https://doi.org/10.1158/2326-6066.CIR-13-0215
Published: 01 July 2014
View articletitled, Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade
Open the PDF for Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade in another window
Includes: Supplementary data