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Journal Articles

Abstract A030: CD4 neoantigen mRNA vaccine enhances endogenous CD8 responses and tumor control

Camille-Charlotte Balanca, Aude-Hélène Capietto, Catherine Carbone, Alan Gutierrez, Yajun Chestnut, Ellen Duong, Aditya Anand, Anthony Antonelli, Jeanne Cheung, Shiuh Luoh, Ariane Nissembaum, Keiko Hokeness, Sara Wichner, Emily Freund, Vincent Javinal, Romain Bouziat, Joshua Gober, Adel ElSohly, Jon Linehan, Ugur Sahin, Lélia Delamarre, Ira Mellman
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (10_Supplement): A030.
https://doi.org/10.1158/2326-6074.TUMIMM24-A030
Published: 18 October 2024
View articletitled, Abstract A030: CD4 neoantigen mRNA vaccine enhances endogenous CD8 responses and tumor control
Journal Articles

Abstract PR-06: Personalized RNA neoantigen vaccines induce long-lived CD8+ T effector cells in pancreatic cancer

Pablo Guasp, Zachary Sethna, Charlotte Reiche, Martina Milighetti, Nicholas Ceglia, Erin Patterson, Nan Pang, George Payne, Ohmoto Akihiro, Luis A Rojas, Masataka Amisaki, Abderezak Zebboudj, Emmanuel Bruno, Linsey Zhang, Zagaa Odgerel, Charlotte Cheng, Evelyna Derhovanessian, Luisa Manning, Felicitas Müller, Ina Rhee, Mahesh Yadav, Mithat Gönen, Olca Basturk, Andre S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, Peter Kingham, Kevin C Soares, William R Jarnagin, Jeffrey Drevin, Eileen M O'Reilly, Ira Mellman, Ugur Sahin, Özlem Türeci, Benjamin D Greenbaum, Vinod P Balachandran
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (10_Supplement): PR-06.
https://doi.org/10.1158/2326-6074.TUMIMM24-PR-06
Published: 18 October 2024
View articletitled, Abstract PR-06: Personalized RNA neoantigen vaccines induce long-lived CD8+ T effector cells in pancreatic cancer
Journal Articles

RNA-encoded Interleukin 2 with Extended Bioavailability Amplifies RNA Vaccine–Induced Antitumor T-cell Immunity

Daniel Peters, Lena M. Kranz, David Eisel, Mustafa Diken, Sebastian Kreiter, Özlem Türeci, Ugur Sahin, Mathias Vormehr
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (10): 1409–1420.
https://doi.org/10.1158/2326-6066.CIR-23-0701
Published: 01 October 2024
View articletitled, RNA-encoded Interleukin 2 with Extended Bioavailability Amplifies RNA Vaccine–Induced Antitumor T-cell Immunity
Open the PDF for RNA-encoded Interleukin 2 with Extended Bioavailability Amplifies RNA Vaccine–Induced Antitumor T-cell Immunity in another window
Includes: Supplementary data
Journal Articles

Abstract B62: Evaluation of systemic RNA-based cancer vaccine induced T-cell responses via mouse T-cell receptor (TCR) profiling

Lena Mareen Kranz, Barbara Schrörs, Thomas Bukur, Christian Albrecht, Lorieta Leppin, Martin Suchan, Marta Faryna, Eileen Powalsky, Rainer Hipfel, Özlem Türeci, Ugur Sahin, Mustafa Diken
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (4_Supplement): B62.
https://doi.org/10.1158/2326-6074.TUMIMM18-B62
Published: 01 April 2020
View articletitled, Abstract B62: Evaluation of systemic RNA-based cancer vaccine induced T-cell responses via mouse T-cell receptor (TCR) profiling
Journal Articles

Abstract A020: Immunomonitoring for actively personalized peptide vaccines (APVACs) during immunotherapeutic treatment of glioblastoma

Alexander Ulges, Norbert Hilf, Wolfgang Wick, Michael Platten, Pierre-Yves Dietrich, Katrin Frenzel, Arie Admon, Sjoerd S.H. van der Burg, Andreas von Deimling, Per thor Straten, Cecile Gouttefangeas, Judith R. Kroep, Francisco Martínez-Ricarte, Hideo Okada, Christian H. Ottensmeier, Berta Ponsati, Hans S. Poulsen, Stefan Stevanovic, Ghazaleh Tabatabai, Hans-Georg Rammensee, Ugur Sahin, Dominik Maurer, Regina Mendrzyk
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (2_Supplement): A020.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR18-A020
Published: 01 February 2019
View articletitled, Abstract A020: Immunomonitoring for actively personalized peptide vaccines (APVACs) during immunotherapeutic treatment of glioblastoma
Journal Articles

Abstract A004: Systemic RNA vaccines: Connecting effective cancer immunotherapy with antiviral defense mechanisms

Lena M. Kranz, Mustafa Diken, Heinrich Haas, Sebastian Kreiter, Carmen Loquai, Kerstin C. Reuter, Martin Meng, Daniel Fritz, Fulvia Vascotto, Hossam Hefesha, Christian Grunwitz, Mathias Vormehr, Yves Hüsemann, Abderraouf Selmi, Andreas N. Kuhn, Janina Buck, Evelyna Derhovanessian, Richard Rae, Sebastian Attig, Jan Diekmann, Robert A. Jabulowsky, Sandra Heesch, Jessica Hassel, Peter Langguth, Stephan Grabbe, Christoph Huber, Özlem Türeci, Ugur Sahin
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): A004.
https://doi.org/10.1158/2326-6066.IMM2016-A004
Published: 31 October 2016
View articletitled, Abstract A004: Systemic RNA vaccines: Connecting effective cancer immunotherapy with antiviral defense mechanisms
Journal Articles

Abstract B040: Oncolytic measles virus for tumor vaccination

Stefan Hutzler, Stephanie Erbar, Robert A. Jabulowsky, Tim Beissert, Jan Hanauer, Oezlem Tuereci, Rita Mitnacht-Kraus, Sebastian Kreiter, Mustafa Diken, Cedrik M. Britten, Ugur Sahin, Michael D. Muehlebach
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): B040.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-B040
Published: 03 January 2016
View articletitled, Abstract B040: Oncolytic measles virus for tumor vaccination
Journal Articles

Abstract B041: A novel nanoparticular formulated tetravalent RNA cancer vaccine for treatment of patients with malignant melanoma

Robert A. Jabulowsky, Carmen Loquai, Mustafa Diken, Lena M. Kranz, Heinrich Haas, Sebastian Attig, Cedrik M. Britten, Janina Buck, Evelyna Derhovanessian, Jan Diekmann, Isaac Esparza, Daniel Fritz, Yves Huesemann, Veronika Jahndel, Klaus Kuehlcke, Andreas N. Kuhn, Peter Langguth, Ulrich Luxemburger, Martin Meng, Felicitas Mueller, Kerstin C. Reuter, Doreen Schwarck, Kristina Spiess, Meike Witt, Jessica C. Hassel, Jochen Utikal, Roland Kaufmann, Marc Schrott, Sebastian Kreiter, Oezlem Tuereci, Christoph Huber, Ugur Sahin
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): B041.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-B041
Published: 03 January 2016
View articletitled, Abstract B041: A novel nanoparticular formulated tetravalent RNA cancer vaccine for treatment of patients with malignant melanoma
Journal Articles

Abstract IA06: Targeting the mutanome for individualized cancer immunotherapy

Ugur Sahin
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): IA06.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-IA06
Published: 03 January 2016
View articletitled, Abstract IA06: Targeting the mutanome for individualized cancer immunotherapy
Journal Articles

Abstract IA46: Towards implementation of T-cell therapy in pancreatic cancer

Rienk Offringa, Isabel Poschke, Michael Volkmar, Oliver Strobel, Frank Bergmann, Niels Halama, Dirk Jäger, Ugur Sahin, Markus Büchler
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): IA46.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-IA46
Published: 03 January 2016
View articletitled, Abstract IA46: Towards implementation of T-cell therapy in pancreatic cancer
Journal Articles

Abstract A110: Mutant MHC class II epitopes drive therapeutic immune responses to cancer

Mathias Vormehr, Sebastian Kreiter, Niels van de Roemer, Mustafa Diken, Martin Löwer, Fulvia Vascotto, Jan Diekmann, Sebastian Boegel, Barbara Schroers, Arbel D. Tadmor, Özlem Türeci, Ugur Sahin
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): A110.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-A110
Published: 03 January 2016
View articletitled, Abstract A110: Mutant MHC class II epitopes drive therapeutic immune responses to cancer
Journal Articles

Functional TCR Retrieval from Single Antigen-Specific Human T Cells Reveals Multiple Novel Epitopes

Petra Simon, Tana A. Omokoko, Andrea Breitkreuz, Lisa Hebich, Sebastian Kreiter, Sebastian Attig, Abdo Konur, Cedrik M. Britten, Claudia Paret, Karl Dhaene, Özlem Türeci, Ugur Sahin
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2014) 2 (12): 1230–1244.
https://doi.org/10.1158/2326-6066.CIR-14-0108
Published: 04 December 2014
View articletitled, Functional TCR Retrieval from Single Antigen-Specific Human T Cells Reveals Multiple Novel Epitopes
Open the PDF for Functional TCR Retrieval from Single Antigen-Specific Human T Cells Reveals Multiple Novel Epitopes in another window
Includes: Supplementary data
Journal Articles

mTOR Inhibition Improves Antitumor Effects of Vaccination with Antigen-Encoding RNA

Mustafa Diken, Sebastian Kreiter, Fulvia Vascotto, Abderraouf Selmi, Sebastian Attig, Jan Diekmann, Christoph Huber, Özlem Türeci, Ugur Sahin
Journal: Cancer Immunology Research
Cancer Immunol Res (2013) 1 (6): 386–392.
https://doi.org/10.1158/2326-6066.CIR-13-0046
Published: 05 December 2013
View articletitled, mTOR Inhibition Improves Antitumor Effects of Vaccination with Antigen-Encoding RNA
Open the PDF for mTOR Inhibition Improves Antitumor Effects of Vaccination with Antigen-Encoding RNA in another window
Includes: Supplementary data