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Toni K. Choueiri
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Journal Articles

Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma

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Renee Maria Saliby, Talal El Zarif, Ziad Bakouny, Valisha Shah, Wanling Xie, Ronan Flippot, Thomas Denize, M. Harry Kane, Katrine N. Madsen, Miriam Ficial, Laure Hirsch, Xiao X. Wei, John A. Steinharter, Lauren C. Harshman, Ulka N. Vaishampayan, Mariano Severgnini, David F. McDermott, Gwo-Shu Mary Lee, Wenxin Xu, Eliezer M. Van Allen, Bradley A. McGregor, Sabina Signoretti, Toni K. Choueiri, Rana R. McKay, David A. Braun
Journal: Cancer Immunology Research
Cancer Immunol Res (2023) 11 (8): 1114–1124.
https://doi.org/10.1158/2326-6066.CIR-22-0996
Published: 03 August 2023
View articletitled, Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma
Open the PDF for Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Linking a Trio of Molecular Features in Clear-Cell Renal Cell Carcinoma

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Chris Labaki, Eliezer M. Van Allen, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (3): 274.
https://doi.org/10.1158/2326-6066.CIR-22-0058
Published: 01 March 2022
View articletitled, Linking a Trio of Molecular Features in Clear-Cell Renal Cell Carcinoma
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Journal Articles

Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors

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Sarah Abou Alaiwi, Amin H. Nassar, Wanling Xie, Ziad Bakouny, Jacob E. Berchuck, David A. Braun, Sylvan C. Baca, Pier Vitale Nuzzo, Ronan Flippot, Tarek H. Mouhieddine, Liam F. Spurr, Yvonne Y. Li, Taiwen Li, Abdallah Flaifel, John A. Steinharter, Claire A. Margolis, Natalie I. Vokes, Heng Du, Sachet A. Shukla, Andrew D. Cherniack, Guru Sonpavde, Robert I. Haddad, Mark M. Awad, Marios Giannakis, F. Stephen Hodi, X. Shirley Liu, Sabina Signoretti, Cigall Kadoch, Matthew L. Freedman, David J. Kwiatkowski, Eliezer M. Van Allen, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (8): 1075–1084.
https://doi.org/10.1158/2326-6066.CIR-19-0866
Published: 03 August 2020
View articletitled, Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors
Open the PDF for Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors in another window
Includes: Supplementary data
Journal Articles

The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non–Clear Cell Renal Cell Carcinoma

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Rana R. McKay, Dominick Bossé, Wanling Xie, Stephanie A.M. Wankowicz, Abdallah Flaifel, Raphael Brandao, Aly-Khan A. Lalani, Dylan J. Martini, Xiao X. Wei, David A. Braun, Eliezer Van Allen, Daniel Castellano, Guillermo De Velasco, J. Connor Wells, Daniel Y. Heng, Andre P. Fay, Fabio A. Schutz, JoAnn Hsu, Sumanta K. Pal, Jae Lyun Lee, James J. Hsieh, Lauren C. Harshman, Sabina Signoretti, Robert J. Motzer, Darren Feldman, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (7): 758–765.
https://doi.org/10.1158/2326-6066.CIR-17-0475
Published: 01 July 2018
View articletitled, The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non–Clear Cell Renal Cell Carcinoma
Open the PDF for The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non–Clear Cell Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Durable Clinical Benefit in Metastatic Renal Cell Carcinoma Patients Who Discontinue PD-1/PD-L1 Therapy for Immune-Related Adverse Events

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Dylan J. Martini, Lana Hamieh, Rana R. McKay, Lauren C. Harshman, Raphael Brandao, Craig K. Norton, John A. Steinharter, Katherine M. Krajewski, Xin Gao, Fabio A. Schutz, Bradley McGregor, Dominick Bossé, Aly-Khan A. Lalani, Guillermo De Velasco, M. Dror Michaelson, David F. McDermott, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (4): 402–408.
https://doi.org/10.1158/2326-6066.CIR-17-0220
Published: 01 April 2018
View articletitled, Durable Clinical Benefit in Metastatic Renal Cell Carcinoma Patients Who Discontinue PD-1/PD-L1 Therapy for Immune-Related Adverse Events
Open the PDF for Durable Clinical Benefit in Metastatic Renal Cell Carcinoma Patients Who Discontinue PD-1/PD-L1 Therapy for Immune-Related Adverse Events in another window
Journal Articles

Comprehensive Meta-analysis of Key Immune-Related Adverse Events from CTLA-4 and PD-1/PD-L1 Inhibitors in Cancer Patients

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Guillermo De Velasco, Youjin Je, Dominick Bossé, Mark M. Awad, Patrick A. Ott, Raphael B. Moreira, Fabio Schutz, Joaquim Bellmunt, Guru P. Sonpavde, F. Stephen Hodi, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2017) 5 (4): 312–318.
https://doi.org/10.1158/2326-6066.CIR-16-0237
Published: 02 April 2017
View articletitled, Comprehensive Meta-analysis of Key Immune-Related Adverse Events from CTLA-4 and PD-1/PD-L1 Inhibitors in Cancer Patients
Open the PDF for Comprehensive Meta-analysis of Key Immune-Related Adverse Events from CTLA-4 and PD-1/PD-L1 Inhibitors in Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups

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Guillermo de Velasco, Diana Miao, Martin H. Voss, A. Ari Hakimi, James J. Hsieh, Nizar M. Tannir, Pheroze Tamboli, Leonard J. Appleman, W. Kimryn Rathmell, Eliezer M. Van Allen, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (10): 820–822.
https://doi.org/10.1158/2326-6066.CIR-16-0110
Published: 02 October 2016
View articletitled, Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups
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Journal Articles

Radiologic Heterogeneity in Responses to Anti–PD-1/PD-L1 Therapy in Metastatic Renal Cell Carcinoma

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Guillermo de Velasco, Katherine M. Krajewski, Laurence Albiges, Mark M. Awad, Joaquim Bellmunt, F. Stephen Hodi, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1): 12–17.
https://doi.org/10.1158/2326-6066.CIR-15-0197
Published: 03 January 2016
View articletitled, Radiologic Heterogeneity in Responses to Anti–PD-1/PD-L1 Therapy in Metastatic Renal Cell Carcinoma
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Journal Articles

Differential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell Carcinoma

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Marcella Callea, Laurence Albiges, Mamta Gupta, Su-Chun Cheng, Elizabeth M. Genega, André P. Fay, Jiaxi Song, Ingrid Carvo, Rupal S. Bhatt, Michael B. Atkins, F. Stephen Hodi, Toni K. Choueiri, David F. McDermott, Gordon J. Freeman, Sabina Signoretti
Journal: Cancer Immunology Research
Cancer Immunol Res (2015) 3 (10): 1158–1164.
https://doi.org/10.1158/2326-6066.CIR-15-0043
Published: 04 October 2015
View articletitled, Differential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell Carcinoma
Open the PDF for Differential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

PD-1 Blockade in Renal Cell Carcinoma: To Equilibrium and Beyond

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Lauren C. Harshman, Charles G. Drake, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2014) 2 (12): 1132–1141.
https://doi.org/10.1158/2326-6066.CIR-14-0193
Published: 04 December 2014
View articletitled, PD-1 Blockade in Renal Cell Carcinoma: To Equilibrium and Beyond
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